Exercise and Life Style Modification in Health and Disease: Focus on the Immunology, Frailty, and Cardiovascular Function

Cardiovascular and immunological disease has been classified as the number-one killer of both men and women worldwide. Over several decades, a greater understanding has been obtained of abilities of exercise, dance intervention, and lifestyle factors to positively influence risk factors for cardiovascular disease, such as immune function, inflammation, oxidative stress, and vascular dysfunction. However, the mechanisms underlying these exercise and lifestyle modification-mediated beneficial effects on these specified risk factors have not been well elucidated, and therefore, mechanistic studies are in urgent need to examine how dietary and lifestyle changes, independently or in combination with each other, influence these processes. Additionally, the mechanisms behind the beneficial effects of physical activity and nutritional intervention on human health, considering aging-associated frailty, immunity and dynapenia (loss of muscle strength) have not been well documented yet. Therefore, this Special Issue examines the health effects of exercise and life style modification on exercise immunology, cardiovascular risks, and skeletal muscular dysfunction and performance. Further insight into these mechanisms will be beneficial for researchers and clinicians alike to develop novel interventions to help to reduce risks for cardiovascular disease, thereby potentially reducing overall disease risk worldwide.

Dr. Yi-Sub Kwak
Dr. Song-Young Park
Dr. Elizabeth Pekas
Guest Editors

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