The Cardiometabolic-Benefits of Exercise Training

Dear Colleagues,

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western world, with excess adiposity being the major risk factor for its development. This excess of adiposity is partially caused by an unhealthy dietary pattern together with a sedentary lifestyle, which is defined as habits and routines related to low levels of exercise time. Nowadays, novel nonpharmacological and pharmacological strategies are needed for reducing this excess of adiposity, which might improve CVD outcomes. One of the best nonpharmacological strategies currently available, together with caloric restriction, is exercise. Epidemiological studies have shown that increased exercise time and decreased sedentary time are linked to lower levels of adiposity and risk of CVD events. Consequently, intervention studies have demonstrated that exercise training is able to reduce adiposity, prevalence of nonalcoholic fatty liver disease, and insulin resistance in addition to enhancing cardiometabolic parameters in humans at different ages. While it is clear exercise induces myriad physiological adaptations that benefit human cardiovascular health either directly or indirectly, it remains crucial to unravel the unknown molecular mechanisms that might explain how exercise induces these beneficial effects since they could be pharmacologically mimicked.

This Special Issue of International Journal of Environmental Research and Public Health (IJERPH) focuses on the current state of knowledge on the link between exercise and cardiovascular health. New research papers, reviews, case reports, brief reports, and commentaries from different exercise disciplines are welcome to this issue. Here are some examples of topics that could be addressed in this Special Issue: i) the cardiovascular benefits of exercise training in preclinical studies—possible mechanisms; ii) cross-sectional studies unraveling the link between exercise or physical activity with cardiovascular outcomes; and iii) exercise interventions for human cardiovascular health.

Dr. Borja Martínez-Téllez
Guest Editor

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