Gut Microbiota in Health and Disease

Dear Colleagues,

The “microbiota revolution” has spread throughout the scientific community, which has led to novel concepts and a new approach in understanding human health and disease. The human microbiota varies taxonomically and functionally in each district of the body (not only the gastrointestinal tract) and undergoes variations in the same individual due to infant transitions, age, diet, and environmental factors, such as antibiotic use, pesticides, food, and drug additives. Recent evidence suggests a crucial role of gut microbiota in health and disease, focusing on the gut as a central organ connecting with the other systems in multiple ways or axes: "gut–brain", "gut–liver", "gut–muscle", "gut–joint", "gut–eye" axes, and so on. We can speculate that changes in gut microbiota composition have a close relationship to health status or disease. Revealing the impact of the environment (diet, additives, drug, pollution, life stressor events) on human gut microbiota could lead to a better comprehension of disease pathogenesis, paving the way for better health strategies. We welcome papers addressing topics for submission to this Special Issue, especially those investigating new diagnostic tools and therapies on the gut microbiota.

Dr. Emanuele Rinninella
Prof. Maria Cristina Mele
Dr. Marco Cintoni
Guest Editors

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