Antimicrobial Resistance: Tackling This Pressing Global Health Challenge

Dear colleagues,

Everyone recognizes the crucial role microbiology plays in our society. One of the biggest global issues that is putting modern medicine at stake and threating global health, food security, and development today is antimicrobial resistance. The emergence of ‘superbugs’ harboring multidrug resistance is spurring the research, discovery, and development of new antibiotics and/or strategies, which are urgently needed. It is paramount to address fundamental gaps in basic scientific research that are hampering new antimicrobial drug discovery. On that basis, the research in this field advances in a variety of approaches, including bacteriophage therapy, fecal microbiota transplantation, antimicrobial peptides (AMPs), immunotherapies, quorum sensing inhibitors, and nanotechnology. At the same time, attention must be given to the traditional screening of new molecules from natural products. Other strategies to tackle the problem of antibiotic resistance include i) the combination of antibiotics with different modes of action or the combination of antibiotics with non-antibiotic compounds that can restore the activity of existing antibiotics and ii) targeting biofilm formation mechanisms and developing antibiofilm agents. Papers addressing these topics are welcome in this Special Issue, especially those providing innovative approaches for new solutions to combat antimicrobial resistance. New research papers, reviews, case reports, methodological papers, and brief reports are invited.

Dr. Lucinda J. Bessa
Guest Editor

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