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Most Cited

  • Review
  • Open Access
17 Citations
25,667 Views
22 Pages

Amidst the obesity and type II diabetes mellitus (T2DM) epidemics, glucagon-like peptide-1 receptor agonists (GLP-1RAs) stand out as a promising therapeutic ally, achieving notable success in glycemic control and weight management. While GLP-1RAs&rsq...

  • Systematic Review
  • Open Access
13 Citations
6,813 Views
19 Pages

Systematic Review of Endoscopic Management of Stricture, Fistula and Abscess in Inflammatory Bowel Disease

  • Partha Pal,
  • Swathi Kanaganti,
  • Rupa Banerjee,
  • Mohan Ramchandani,
  • Zaheer Nabi,
  • Duvvuru Nageshwar Reddy and
  • Manu Tandan

Background: Interventional inflammatory bowel disease (IIBD) therapies can play a key role in inflammatory bowel disease (IBD) related stricture/fistula/abscess deferring or avoiding invasive surgery. Methods: A total of 112 studies pertaining to IIB...

  • Review
  • Open Access
12 Citations
19,489 Views
16 Pages

An Updated Review on Probiotic Production and Applications

  • Guru Prasad Venkatesh,
  • Gouthami Kuruvalli,
  • Khajamohiddin Syed and
  • Vaddi Damodara Reddy

Microorganisms are ubiquitous and have been exploited for centuries to generate primary and secondary metabolites essential for human welfare and environmental sustainability. Microorganisms occupy a prominent position in the industrial sector due to...

  • Review
  • Open Access
10 Citations
99,445 Views
16 Pages

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

  • Chetan Kantharia,
  • Munesh Kumar,
  • Mukesh Kumar Jain,
  • Lokendra Sharma,
  • Lokesh Jain and
  • Anish Desai

Chronic liver disease (CLD) is a growing concern worldwide. The common etiological factors include infection, alcohol abuse, exposure to hepatotoxic drugs, autoimmune disorders, and metabolic diseases. The chronic liver disease progresses to liver ci...

  • Review
  • Open Access
9 Citations
18,111 Views
13 Pages

Esophageal Food Impaction and Foreign Object Ingestion in Gastrointestinal Tract: A Review of Clinical and Endoscopic Management

  • Livia Marieta Negoita,
  • Catalin Stefan Ghenea,
  • Gabriel Constantinescu,
  • Vasile Sandru,
  • Madalina Stan-Ilie,
  • Oana-Mihaela Plotogea,
  • Umar Shamim,
  • Bogdan Florin Dumbrava and
  • Mariana Mihaila

Foreign bodies in the digestive tract represent a frequent pathology for the emergency service. Foreign bodies are represented by impacted food bolus or voluntarily and involuntarily swallowed objects. Involuntary swallowing of objects occurs most fr...

  • Review
  • Open Access
9 Citations
17,694 Views
17 Pages

Nutritional Consequences of Celiac Disease and Gluten-Free Diet

  • Paola Ilaria Bianchi,
  • Nicola Aronico,
  • Giovanni Santacroce,
  • Giacomo Broglio,
  • Marco Vincenzo Lenti and
  • Antonio Di Sabatino

Celiac disease is an immune-mediated condition triggered by gluten ingestion in genetically predisposed individuals. The global prevalence of celiac disease is significant, affecting approximately 1.4% of women and 0.7% of men, with incidence rates o...

  • Review
  • Open Access
8 Citations
6,097 Views
39 Pages

Autophagy and Apoptosis in Inflammatory Bowel Disease

  • Elias Kouroumalis,
  • Ioannis Tsomidis and
  • Argyro Voumvouraki

The pathogenesis of inflammatory bowel disease (IBD) implicates several interconnecting factors. Immunity and external factors interact, and most aspects are still under investigation. Autophagy and apoptosis are two critical pathways that decide the...

  • Review
  • Open Access
8 Citations
10,739 Views
18 Pages

The quality of upper gastrointestinal endoscopy (EGD) is crucial and carries significant consequences for patient outcomes, the employment of healthcare resources, and the future course of gastroenterology as a medical specialty. In this review, we n...

  • Review
  • Open Access
8 Citations
9,714 Views
12 Pages

Herbs and Spices: Modulation of Gut Microbiota for Healthy Aging

  • Samjhana Pradhan,
  • Cynthia Blanton,
  • Javier Ochoa-Reparaz,
  • Nirajan Bhattarai and
  • Kavita Sharma

The gut microbiota interacts with the host’s immune function, and evidence supports a relationship between the gut microbiota and age-related disease. Consumption of herbs and spices, which contain bioactive compounds such as polyphenols, is as...

  • Review
  • Open Access
8 Citations
11,112 Views
15 Pages

Mucosal Immunity and Trained Innate Immunity of the Gut

  • Tsvetelina Velikova,
  • Issa El Kaouri,
  • Konstantina Bakopoulou,
  • Milena Gulinac,
  • Kremena Naydenova,
  • Martin Dimitrov,
  • Milena Peruhova and
  • Snezhina Lazova

Mucosal immunity and trained innate immunity of the gut play a pivotal role in maintaining intestinal homeostasis and defending against microbial pathogens. This review provides an overview of the mechanisms underlying mucosal immunity and the concep...

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Gastroenterol. Insights - ISSN 2036-7422