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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interdisciplinary Approaches to Improve Cardiovascular Outcomes

edited by

Mihaela Hostiuc

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2389 | Submission Open

Keywords: cardiovascular disease; prevention; risk factors; cardiovascular outcomes; interdisciplinarity; burden of disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2291 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Medical Image Analysis and Clinical Decision Support

edited by Zahid Ullah and Tahir Mahmood

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2282 | Submission Open

Keywords: medical image analysis; deep learning; vision transformers; medical image segmentation; clinical decision support; multimodal learning; explainable AI; continual learning; federated learning; healthcare AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2251 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Imaging and Interpretation in Pediatric Radiology

edited by

André Lollert

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2203 | Submission Open

Keywords: pediatric radiology; pediatric MRI; pediatric CT; photon-counting CT; pediatric ultrasound; clinico-radiologic diagnostics; rare diseases; quantitative imaging; artificial intelligence; nuclear medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Viral Respiratory Infections, 2nd Edition

edited by

Federica Novazzi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2142 | Submission Open

Keywords: respiratory tract infections; lower respiratory tract infections (LRTIs); upper respiratory tract infections (URTIs); whole-genome sequencing (WGS); immunological techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

(Bio)sensors for Medical Diagnostics

edited by

Mihaela Badea

Akhtar Hayat

and Sehrish Bilal

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2120 | Submission Open

Keywords: sensors and biosensors; medical diagnostics; biomarker detection; point-of-care testing; lab-on-a-chip; wearable health technology; nanotechnology; signal transduction; early disease detection; clinical monitoring

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2108 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Sports Medicine: Diagnosis and Management

edited by Anca Ionescu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2097 | Submission Open

Keywords: sports medicine; sports cardiology; exercise physiology; artificial intelligence; athlete health; performance monitoring; biomarkers; sports nutrition; injury prevention; rehabilitation; wearable technology; clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Anatomy and Diagnosis in 2026

edited by Ji-Hyun Lee

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2003 | Submission Open

Keywords: clinical anatomy; radiological anatomy; applied anatomy; anatomical variations; pathoanatomy; artificial intelligence in anatomy; anatomical research innovation; anatomical education

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI-Powered Ophthalmic Diagnostics: From Image Segmentation to Disease Classification

edited by

Yanwu Xu

Weihua Yang

and

Huihui Fang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1685 | Submission Open

Keywords: ophthalmic artificial intelligence; medical image segmentation; disease classification; ocular imaging; deep learning and foundation models; explainable AI (XAI); clinical translation in ophthalmology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Diagnosis and Treatment of Otolaryngology Diseases

edited by Lichun Hsieh

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1619 | Submission Open

Keywords: otolaryngology; diagnostic imaging; minimally invasive surgery; precision medicine; head and neck diseases; clinical management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic and Operative Hysteroscopy, 2nd Edition

edited by

Panagiotis Christopoulos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1608 | Submission Open

Keywords: hysteroscopy; diagnosis; technique; malformation; uterus; endometrial; anomaly; minimally invasive; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1577 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management of Liver Diseases

edited by

Jiang Liu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1559 | Submission Open

Keywords: primary liver cancer; metastatic liver cancer; liver transplantation; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1541 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Chronic Kidney Diseases: Diagnosis, Management, and Prognosis

edited by

Xujie Zhou

submission deadline 31 Dec 2026 | Viewed by 1479 | Submission Open

Keywords: chronic kidney diseases; IgA nephropathy; biomarkers; molecular mechanisms; therapeutic innovation; personalized medicine; translational research

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence, 2nd Edition

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1357 | Submission Open

Keywords: biomarkers; diagnosis; personalized medicine; therapeutic strategies; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1328 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1313 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Maternal–Fetal Medicine: 3rd Edition

edited by

Elena Bernad

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1311 | Submission Open

Keywords: maternal–fetal medicine; high-risk pregnancy; prenatal diagnostics; psychological distress in pregnancy; anxiety and depression; stress-related disorders; biomarkers; perinatal morbidity and mortality; translational diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1201 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Oral and Maxillofacial Surgery: Diagnosis and Management

edited by Kenji Yamagata

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1198 | Submission Open

Keywords: oral and maxillofacial surgery; oral diseases; oral cancer; jaw deformity; orthognathic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | Viewed by 1183 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases

edited by

Liangjing Lu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1123 | Submission Open

Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Fetal Diagnosis and Therapy: 2nd Edition

edited by Elisa Montaguti and Camilla Dionisi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1090 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Whole-Body PET/CT: From Diagnosis to Prognosis

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1075 | Submission Open

Keywords: whole-body PET/CT; diagnosis; prognosis; human diseases; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Women’s Cardiovascular Health: Advances in Diagnosis, Screening, and Risk Prediction

edited by

Jasjit S. Suri

and

Luca Saba

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1041 | Submission Open

Keywords: artificial intelligence; women’s cardiovascular health; diagnosis; screening; risk prediction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Advances in Orthodontics and Dentistry

edited by

Antonino Lo Giudice

submission deadline 31 Dec 2026 | 2 articles | Viewed by 980 | Submission Open

Keywords: CBCT facial scanning; oral imaging; orthodontics; digital dentistry; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Prostate Cancer: Innovations in Diagnosis and Risk Stratification

edited by Biren Saraiya

submission deadline 31 Dec 2026 | 1 articles | Viewed by 900 | Submission Open

Keywords: prostate cancer; diagnostics; therapeutics; molecular targets; Prostate Specific Membrane Antigen (PSMA); risk stratification; radioligand therapy; multimodal therapy; clinical guidelines

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Prognostic and Predictive Biomarkers, 4th Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Dec 2026 | 2 articles | Viewed by 791 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Eye Disease, Fifth Edition

edited by

Jae-Ho Han

submission deadline 31 Dec 2026 | 1 articles | Viewed by 754 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Technologies for Lung Disease Detection and Clinical Assessment

edited by Scott Matson and

Joshua Jay Reicher

submission deadline 31 Dec 2026 | 1 articles | Viewed by 689 | Submission Open

Keywords: medical imaging; artificial intelligence (AI); radiology; machine learning (ML)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Accurate Diagnosis and Management of Infectious and Respiratory Diseases

edited by

Marco Goeijenbier

submission deadline 31 Dec 2026 | 1 articles | Viewed by 531 | Submission Open

Keywords: infectious and respiratory diseases; viral and bacterial pathogens; multiplex molecular panels; rapid diagnostic tests; intensive care units

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Dec 2026 | Viewed by 514 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Laboratory Diagnosis—2nd Edition

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 502 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

From Early Diagnosis to Therapy Response: Machine Learning Driven Biomarker Discovery

edited by Wenjie Shi and Rudy Leon De Wilde

submission deadline 31 Dec 2026 | 1 articles | Viewed by 501 | Submission Open

Keywords: machine learning; biomarker discovery; early diagnosis; liquid biopsy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 31 Dec 2026 | Viewed by 499 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Cancer Diagnosis and Intervention

edited by Vlad Alexandru Gâta

submission deadline 31 Dec 2026 | 1 articles | Viewed by 491 | Submission Open

Keywords: diagnostic; precision oncology; artificial intelligence; radiomics; molecular biomarkers; interventional oncology; personalized medicine; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning and Large Models in Ophthalmic Innovations

edited by

Yanwu Xu

Weihua Yang

and Huihui Fang

submission deadline 31 Dec 2026 | Viewed by 415 | Submission Open

Keywords: Artificial Intelligence in ophthalmology; multimodal learning; foundation models; ophthalmic imaging; eye disease diagnosis and treatment

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 31 Dec 2026 | Viewed by 413 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathogenesis, Diagnosis, and Management of Rheumatic Disease: Progress and Challenges

edited by Miguel Ángel González-Gay

submission deadline 31 Dec 2026 | Viewed by 399 | Submission Open

Keywords: rheumatic disease; systemic vasculitis; rheumatoid arthritis; metabolic syndrome; atherosclerosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic and Prognostic Tools in Gynecological Cancer

edited by

Ahmad Sayasneh

submission deadline 31 Dec 2026 | Viewed by 379 | Submission Open

Keywords: gynaecological cancer; diagnostic imaging; artificial intelligence; molecular biomarkers; prognostic models; surgical navigation; precision oncology; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Gastrointestinal Endoscopy: Diagnostic Applications and Safety Evaluation

edited by

Giacomo Emanuele Maria Rizzo

Lucía Guilabert

and Sara Nikolic

submission deadline 31 Dec 2026 | Viewed by 345 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; luminal endoscopy; procedural safety; risk assessment; adverse events; sedation protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

Selected Papers From the 1st International Online Conference on Diagnostics [IOCDi 2026]

edited by

Giorgio Treglia

submission deadline 31 Dec 2026 | Viewed by 329 | Submission Open

Keywords: imaging diagnosis; pathology diagnosis; molecular diagnosis; clinical diagnosis; laboratory medicine; point-of-care diagnosis; artificial intelligence

Advances in the Diagnosis, Prognosis, and Management of the Musculoskeletal System

edited by

Massimiliano Leigheb

Alessandro de Sire

and Cesar de Cesar Netto

submission deadline 31 Dec 2026 | Viewed by 302 | Submission Open

Keywords: musculoskeletal system; diagnostic tools; prognosis; artificial intelligence; augmented reality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Data Science and Artificial Intelligence in Laboratory Medicine

edited by

Fernando Marques-Garcia

submission deadline 31 Dec 2026 | Viewed by 292 | Submission Open

Keywords: artificial intelligence; data science; algorithm; laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Liquid Biopsy and Molecular Diagnostics in Neuro-Oncology

edited by Santiago Cabezas-Camarero and Juan Manuel Sepúlveda-Sánchez

submission deadline 31 Dec 2026 | Viewed by 283 | Submission Open

Keywords: liquid biopsy; biofluids; biomarkers; molecular techniques; gliomas; neuro-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopic Diagnosis and Management of Tumors

edited by

Longjun He

submission deadline 31 Dec 2026 | Viewed by 279 | Submission Open

Keywords: endoscopy; tumor diagnosis; endoscopic therapy; endoscopic ultrasound; artificial intelligence; early cancer detection; minimally invasive surgery; precision oncology; molecular imaging; translational research

(This special issue belongs to the Section Biomedical Optics)

Innovative Approaches to Vascular Diseases Diagnosis and Management

edited by

Paolo Perini

and

Chiara Martini

submission deadline 31 Dec 2026 | Viewed by 267 | Submission Open

Keywords: vascular imaging; vascular surgery; aortic aneurysm; peripheral arterial disease; venous disease; image-guided therapy; artificial intelligence; 3D printing; medical devices; vascular complications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Displaying special issue 401-450 on page 9 of 13.

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