Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Preclinical and Clinical Stroke Imaging
edited by
submission deadline 31 Oct 2025 | Viewed by 454 | Submission Open
Keywords: cerebral ischemia; cerebral infarction; ischemic stroke; hemorrhagic stroke; MRI; CT; ischemic penumbra; stroke recovery
(This special issue belongs to the Section Medical Imaging and Theranostics)
Type 2 Inflammatory Disorders: From Eosinophilic Gastrointestinal Disorders (EGIDs) and Beyond
edited by Edoardo Vespa and
submission deadline 31 Oct 2025 | Viewed by 453 | Submission Open
Keywords: eosinophilic esophagitis; EGIDs; asthma; CRSwNP; type 2 disorders; eosinophilic diseases
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Recent Advances in the Diagnosis and Management of Gynecological Cancers
edited by Zelal M. Muallem
submission deadline 31 Oct 2025 | 1 articles | Viewed by 387 | Submission Open
Keywords: gynecological cancers; diagnosis and staging; molecular biomarkers; targeted therapies; immunotherapy; minimally invasive surgery; personalized medicine; cancer resistance; quality of life in oncology; disparities in cancer care
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases
edited by Francesco Giurazza and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 287 | Submission Open
Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization
(This special issue belongs to the Section Medical Imaging and Theranostics)
3rd Edition: AI/ML-Based Medical Image Processing and Analysis
edited by and Jaafar Alghazo
submission deadline 31 Oct 2025 | 1 articles | Viewed by 282 | Submission Open
Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition
edited by Costantino Ricci
submission deadline 31 Oct 2025 | Viewed by 280 | Submission Open
Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnosis and Management in Digestive Surgery: 2nd Edition
edited by and Florin Grama
submission deadline 31 Oct 2025 | Viewed by 266 | Submission Open
Keywords: digestive diseases; novel changes in diagnosis; updates on daily practice; management of digestive diseases
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Musculoskeletal Imaging: From Diagnosis to Treatment
edited by and Massimo De Filippo
submission deadline 31 Oct 2025 | 1 articles | Viewed by 261 | Submission Open
Keywords: musculoskeletal imaging; artificial intelligence; bone imaging; musculoskeletal ultrasound; diagnosis; machine learning algorithms
(This special issue belongs to the Section Medical Imaging and Theranostics)
Brain MRI: Current Development and Applications
edited by
submission deadline 31 Oct 2025 | Viewed by 236 | Submission Open
Keywords: neuroimaging; diagnostic MRI; artificial intelligence; neurological disorders
(This special issue belongs to the Section Medical Imaging and Theranostics)
Endoscopic Diagnosis and Management of Ear Disease
edited by and
submission deadline 31 Oct 2025 | Viewed by 235 | Submission Open
Keywords: endoscopic otology; endoscopic ear surgery; ear disease diagnosis; minimally invasive surgery; otolaryngology advances; clinical case studies; surgical innovation; patient outcomes; diagnostic techniques; ear disease management; medical research in otology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnosis and Prognosis of Gynecological and Obstetric Diseases
edited by and Valentina Billone
submission deadline 31 Oct 2025 | 1 articles | Viewed by 191 | Submission Open
Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Wearable Devices for Health Monitoring and Disease Diagnosis
edited by Robert LeMoyne
submission deadline 31 Oct 2025 | Viewed by 184 | Submission Open
Keywords: wearable devices; health monitoring; diagnosis; sensors; artificial intelligence
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Chronic Fatigue Syndrome: Clinical Diagnostics, Management, and Prognosis submission deadline 31 Oct 2025 | Viewed by 167 | Submission Open
Keywords: chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME); post-COVID-19 illness; post-infection syndromes; autonomic nervous system; Lyme disease; immunology; gut microbiota; chronic infection
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Optical Coherence Tomography Angiography (OCTA): Advances and Applications in Retinal and Systemic Diseases
edited by , Stanislao Rizzo and Fabrizio Giansanti
submission deadline 31 Oct 2025 | Viewed by 141 | Submission Open
Keywords: optical coherence tomography angiography; retinal and systemic diseases; diagnosis; screening; marker; prognosis
(This special issue belongs to the Section Biomedical Optics)
Photon-Counting CT in Clinical Application
edited by Philipp Gruschwitz
submission deadline 31 Oct 2025 | Viewed by 124 | Submission Open
Keywords: protocol development and optimization; spectral imaging; tissue characterization; lesion classification; benefits of special resolution; radiation dose optimization; contrast agent
(This special issue belongs to the Section Medical Imaging and Theranostics)
Musculoskeletal Disorders: Diagnosis, Management, and Rehabilitation, 2nd Edition
edited by
submission deadline 31 Oct 2025 | Viewed by 117 | Submission Open
Keywords: musculoskeletal disorders; pain; disability; diagnosis; interventions; rehabilitation strategies; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
AI-Powered Clinical Diagnosis and Decision-Support Systems
edited by
submission deadline 31 Oct 2025 | Viewed by 112 | Submission Open
Keywords: artificial intelligence; clinical decision support system; medical diagnostics
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Recent Advancements of Molecular Biomarkers in Cancer, 2nd Edition
edited by Giuseppe Nicolò Fanelli
submission deadline 31 Oct 2025 | Viewed by 98 | Submission Open
Keywords: molecular biomarkers; cancer research; precision medicine; tumor profiling; genomic signatures; personalized oncology; biomarker discovery
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Radiology in the Third Millennium: New Patient-Centered Diagnostic Approaches submission deadline 31 Oct 2025 | Viewed by 95 | Submission Open
Keywords: radiology; diagnostics; patient-specific imaging; AI; deep learning
(This special issue belongs to the Section Medical Imaging and Theranostics)
Ultrasound in Otolaryngology-Head and Neck Surgery
edited by , Enyinnaya Ofo and Mathias P. von Beckerath
submission deadline 31 Oct 2025 | Viewed by 93 | Submission Open
Keywords: head and neck ultrasound; surgeon-performed ultrasound; otolaryngology– head and neck surgery; minimally invasive procedures; ultrasound-guided interventions
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Advances in Endocrinology Pathology submission deadline 31 Oct 2025 | Viewed by 90 | Submission Open
Keywords: histological classification and reporting; cytological analysis; fine-needle aspiration; molecular markers; immunohistochemistry; hormone; dynamic hormonal testing; endocrine tumors
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
New Advances in Diagnostic Bronchoscopy
edited by
submission deadline 31 Oct 2025 | Viewed by 85 | Submission Open
Keywords: diagnostic bronchoscopy; advanced imaging techniques; interventional bronchoscopy; minimally invasive techniques
(This special issue belongs to the Section Biomedical Optics)
Advances in Non-Invasive Diagnostic Technologies for Heart Diseases
edited by Dentamaro Ilaria
submission deadline 31 Oct 2025 | Viewed by 74 | Submission Open
Keywords: transthoracic echocardiography; cardiac magnetic resonance; multimodality cardiovascular imaging; cardiac CT; transesophageal echocardiography; cardiovascular disease
(This special issue belongs to the Section Medical Imaging and Theranostics)
The Role of AI and Radiomics in Diagnostic Oncology
edited by Laura Travascio and
submission deadline 31 Oct 2025 | Viewed by 68 | Submission Open
Keywords: artificial intelligence; pathophysiological; radiology and nuclear medicine; diagnostic imaging; diagnostic oncology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy
edited by
submission deadline 31 Oct 2025 | Viewed by 63 | Submission Open
Keywords: kidney; nephrology; ultrasounds; radiology
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Applications of Artificial Intelligence and Non-Invasive Electrocardiograms in Disease Diagnosis
edited by and Samuel L. Johnston
submission deadline 31 Oct 2025 | Viewed by 56 | Submission Open
Keywords: artificial intelligence (AI); non-invasive electrocardiogram (ECG); disease diagnosis; medical imaging analysis; machine learning; deep learning; cardiovascular diseases; pattern recognition; data analytics
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnosis and Management of Pulmonary Adenocarcinoma
edited by
submission deadline 31 Oct 2025 | Viewed by 55 | Submission Open
Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Laboratory Investigations in Nephrology
edited by
submission deadline 31 Oct 2025 | Viewed by 55 | Submission Open
Keywords: nephrology; laboratory diagnostics; novel biomarkers; chronic kidney disease; renal pathology; artificial intelligence and machine learning
(This special issue belongs to the Section Clinical Laboratory Medicine)
Sports Related Musculoskeletal Disorders: Diagnosis, Treatment and Management
edited by
submission deadline 31 Oct 2025 | Viewed by 55 | Submission Open
Keywords: orthopedics; rehabilitation medicine; musculoskeletal disorders
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Applications of Artificial Intelligence in Orthopedics
edited by Zhonghai Li
submission deadline 31 Oct 2025 | Viewed by 54 | Submission Open
Keywords: artificial intelligence; orthopedics; medical diagnosis; image analysis; predictive modeling
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
New Insights into Gastrointestinal Endoscopy submission deadline 31 Oct 2025 | Viewed by 50 | Submission Open
Keywords: diagnosis; prognosis; gastrointestinal endoscopy; markers; clinical practice and patient care
(This special issue belongs to the Section Biomedical Optics)
Emerging Predictive Biomarkers in Breast Cancer
edited by and Maria Vita Sanò
submission deadline 31 Oct 2025 | Viewed by 49 | Submission Open
Keywords: breast cancer; HER2-positive; TNBC; ER+; HER2-negative; HER2-low; PD-L1; 18F-FES PET; hormonotherapy; immunotherapy; immune checkpoint inhibitors; liquid biopsy; circulating tumor cells; ctDNA; antibody drug conjugates; PARP inhibitors; CDK4/6 inhibitors; predictive biomarkers
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
New Insights into the Diagnosis of Neurological Disorders
edited by Yukai Cheng
submission deadline 31 Oct 2025 | Viewed by 42 | Submission Open
Keywords: neurological disorders; genomics; molecular biology; artificial intelligence; machine learning
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advancements in Maternal–Fetal Medicine: 2nd Edition
edited by
submission deadline 31 Oct 2025 | Viewed by 42 | Submission Open
Keywords: pregnancy; fetus; ultrasound; maternal– fetal medicine; perinatal care high risk; obstetrics; complication; screening; diagnostics; fetal distress
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Neurological Diseases: Novel Biomarkers for Diagnosis and Management submission deadline 31 Oct 2025 | Viewed by 38 | Submission Open
Keywords: biomarkers; laboratory medicine; neuroimaging; neurological diseases; treatment; management; clinical diagnostics
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Laboratory Analysis and Diagnostics
edited by Ivana Lapić
submission deadline 31 Oct 2025 | Viewed by 38 | Submission Open
Keywords: laboratory analysis; diagnostics; analytical techniques; diagnostic methods
(This special issue belongs to the Section Clinical Laboratory Medicine)
Cardiovascular Diseases: Advances in Echocardiography and Cardiac Computed Tomography
edited by Vasileios Kamperidis
submission deadline 31 Oct 2025 | Viewed by 29 | Submission Open
Keywords: heart failure; echocardiography; valvular heart disease; strain imaging; cardiac computed tomography; atherosclerosis; cardiomyopathy; 3D imaging; coronary artery disease; CT FFR; perfusion imaging; stress echocardiography; TEE
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Diagnosis of Digestive Diseases
edited by Noriaki Manabe
submission deadline 31 Oct 2025 | Viewed by 27 | Submission Open
Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnosis and Treatment of Neurodevelopmental Disorders submission deadline 31 Oct 2025 | Viewed by 26 | Submission Open
Keywords: neurodevelopmental disorders; psychopathological; biomarkers for early diagnosis; machine learning; fMRI; EEG; MRI; eye-tracking
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Neonatal Diagnostics
edited by Yogen Singh
submission deadline 31 Oct 2025 | Viewed by 26 | Submission Open
Keywords: neonatal imaging; point-of-care ultrasound (POCUS); targeted neonatal echocardiography; hemodynamic evaluation; functional MRI (fMRI); diffusion tensor imaging (DTI); genomic testing; neonatal intensive care units (NICUs)
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Computer-Aided Diagnosis in Endoscopy 2025
edited by
submission deadline 10 Nov 2025 | Viewed by 81 | Submission Open
Keywords: AI; deep learning; endoscopy; machine learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Applications of PET/CT in Clinical Diagnostics
edited by Jasna M. Mihailovic and Partha S Choudhury
submission deadline 13 Nov 2025 | 1 articles | Viewed by 528 | Submission Open
Keywords: F-18; fluorodeoxyglucose; PET/CT imaging; oncology; radiotracers beyond F-18 fluorodeoxyglucose; clinical diagnostics
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in the Laboratory Diagnosis
edited by and Camilla Mattiuzzi
submission deadline 30 Nov 2025 | 11 articles | Viewed by 14350 | Submission Open
Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in the Diagnosis and Treatment of Infections of the Central Nervous System
edited by and Raffaella Capasso
submission deadline 30 Nov 2025 | 1 articles | Viewed by 12609 | Submission Open
Keywords: central nervous system infections; meningitis; HIV; tuberculosis; magnetic resonance imaging
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Research Update on Nuclear Medicine
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 12406 | Submission Open
Keywords: nuclear medicine; diagnostic radiology; PET/CT; SPECT; PET; imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Frontline of Breast Imaging
edited by
submission deadline 30 Nov 2025 | 4 articles | Viewed by 8478 | Submission Open
Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures
(This special issue belongs to the Section Medical Imaging and Theranostics)
Vascular Diagnostic Imaging
edited by
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7117 | Submission Open
Keywords: flow-mediated dilation (FMD); optical coherence tomography (OCT); intravascular ultrasound (IVUS)
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnosis and Management of Arrhythmias
edited by Laura Vitali-Serdoz, Martina Nesti and Dirk Bastian
submission deadline 30 Nov 2025 | 6 articles | Viewed by 6233 | Submission Open
Keywords: arrhythmia; electrocardiogram (ECG); cardiac implantable devices; antiarrhythmic drugs; cardiac monitoring; implantable loop recorder; digital health; wearable devices; electrophysiology study; catheter ablation; ventricular tachycardia; atrial fibrillation; supraventricular tachycardia; syncope
(This special issue belongs to the Section Medical Imaging and Theranostics)
Predictive and Prognostic Markers in Critically Ill Patients, 2nd Edition
edited by and Sergio Lassola
submission deadline 30 Nov 2025 | 4 articles | Viewed by 5597 | Submission Open
Keywords: acute brain injury; acute kidney injury; acute mesenteric ischemia; acute pancreatitis; acute respiratory failure; heart failure; infectious disease
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 2nd Edition submission deadline 30 Nov 2025 | 4 articles | Viewed by 4675 | Submission Open
Keywords: machine learning; neurodegenerative diseases; diagnosis; detection and evaluation; monitoring
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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