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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Multimodal Cardiac Imaging: Diagnostic and Prognostic Advances

edited by

Lucia La Mura

and Ciro Santoro

submission deadline 31 Jan 2026 | Viewed by 1352 | Submission Open

Keywords: cardiovascular imaging; cardiac CT; cardiac magnetic resonance; cardiac MRI; echocardiography; multimodality cardiovascular imaging; advanced echocardiography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Advances in Allergy Diagnosis

edited by

Zenon Brzoza

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1328 | Submission Open

Keywords: allergic diseases; allergy diagnosis; biomarker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Critical Ultrasound in Newborns/Children

edited by

Jing Liu

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1313 | Submission Open

Keywords: lung ultrasound; pulmonary ultrasound; point-of-care lung ultrasound; newborn infants; neonates; lung diseases; pneumonia; ventilator-associated pneumonia; respiratory distress syndrome; meconium aspiration syndrome; pulmonary hemorrhage; bronchopulmonary dysplasia; tracheobronchial pneumonia; congenital pulmonary malformation; pleural effusion; pneumothorax; pulmonary edema

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Biomarkers of Urological Diseases

edited by

Martin Pejchinovski

and

Jochen Metzger

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1254 | Submission Open

Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Diseases: Innovations in Diagnosis and Management

edited by Hisao Hara

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1244 | Submission Open

Keywords: myocardial infarction; biomarker; prognosis; coronary risk; residual risk; prognosis prediction

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in Retinal Imaging

edited by

Rodolfo Mastropasqua

and

Maria Ludovica Ruggeri

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1197 | Submission Open

Keywords: retina; vitreoretinal diseases; inherited retinal dystrophies; diabetic retinopathy; age-related macular degeneration; retinal detachment; optical coherence tomography; imaging

(This special issue belongs to the Section Biomedical Optics)

Genetic Diagnosis of Rare Neurological Disorders: Advances, Challenges, and Clinical Impact

edited by

Georgia Xiromerisiou

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1071 | Submission Open

Keywords: rare neurological disorders; genetic diagnosis; neurogenetics; next-generation sequencing; genotype– phenotype correlation; molecular diagnostics; clinical impact; personalized medicine; translational research; undiagnosed diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Aspects of CTC Research for Basic Medicine and Clinical Application

edited by Hayao Nakanishi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1019 | Submission Open

Keywords: CTC; metastasis; mobilization; cluster heterogeneity; routine blood test; genetic analysis; CTC organoid

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diabetes Mellitus: Clinical Diagnostics and Management

edited by

Syed M. Shahid

submission deadline 31 Jan 2026 | 1 articles | Viewed by 880 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; precision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Clinical Biochemistry, 2nd Edition

edited by Yu Chen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 811 | Submission Open

Keywords: clinical biochemistry; medical diagnosis; biomarkers; proteomic profiling; metabolomic profiling; high throughput technologies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Clinical and Interventional Gastroenterology

edited by

Antonio Facciorusso

and

Eyad Gadour

submission deadline 31 Jan 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: diagnostic endoscopy; AI in gastroenterology; biomarker discovery; capsule endoscopy; confocal laser endomicroscopy; early cancer detection; functional GI disorders; molecular diagnostics; non-invasive imaging; microbiome analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2026 | 1 articles | Viewed by 612 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnosis and Treatment Plan for Orthodontic and Oro-Facial Rehabilitations—2nd Edition

edited by

Antonino Lo Giudice

submission deadline 31 Jan 2026 | 1 articles | Viewed by 479 | Submission Open

Keywords: CBCT; facial scan; oral imaging; orthodontics; digital dentistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Progress in Abdominal Ultrasound

edited by Andrea Boccatonda,

Antonio Corvino

and

Giulio Cocco

submission deadline 31 Jan 2026 | Viewed by 420 | Submission Open

Keywords: ultrasound; abdomen; CEUS; doppler; bowel

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition

edited by

Stefano Francesco Crinò

submission deadline 31 Jan 2026 | 1 articles | Viewed by 348 | Submission Open

Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 346 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Cardiovascular Diagnosis and Risk Stratification

edited by

Sonu M. M. Bhaskar

submission deadline 31 Jan 2026 | Viewed by 300 | Submission Open

Keywords: cardiovascular diseases; cardiac MRI; CT angiography; and molecular imaging; biomarker discovery; artificial intelligence and machine learning; wearable devices and mobile health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Breast Diagnostics

edited by Takouhie Catherine Maldjian, Jessica Leung, Mary M. Salvatore and Judy Yee

submission deadline 31 Jan 2026 | Viewed by 287 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; breast imaging; breast cancer; breast cancer prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic, Predictive and Prognostic Biomarkers for Neurodegenerative Diseases

edited by

Ionica Pirici

submission deadline 31 Jan 2026 | 1 articles | Viewed by 201 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; medical imaging; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiac Magnetic Resonance Imaging: Current and Future Clinical Applications

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 197 | Submission Open

Keywords: cardiomyopathy; cardiovascular physiology; ischemic heart disease; metabolic heart disease; stress MRI; heart failure with reduced ejection fraction; heart failure with preserved ejection fraction

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multidisciplinarity in Myeloid Neoplasms: Bridging Diagnostics and Clinical Insights

edited by Alexander Haushofer and Bernhard Strasser

submission deadline 31 Jan 2026 | Viewed by 194 | Submission Open

Keywords: acute myeloid leukemia (AML); myelodysplastic syndromes (MDS); myeloproliferative neoplasms (MPN); MDS/MPN genetic profiling; multidisciplinary collaboration; diagnostic innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic and Interventional Nephrology

edited by Ammar Almehmi

submission deadline 31 Jan 2026 | Viewed by 178 | Submission Open

Keywords: dialysis access; fistula; graft; stent; peritoneal catheter; drug-coated balloon; EndoAVF; dialysis; vascular access dysfunction; interventional nephrology; diagnostic imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Jan 2026 | Viewed by 164 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Multimodal Biomarkers, AI, and Quantum Biology for Brain Diagnostics

edited by

Igor Goryanin

submission deadline 31 Jan 2026 | Viewed by 163 | Submission Open

Keywords: artificial intelligence; quantum biology; neurodiagnostics; biomarkers; neuroimaging; electrophysiology; diagnostics; brain networks

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advanced Imaging in the Diagnosis and Management of Skin Diseases

edited by Lehang Guo

submission deadline 31 Jan 2026 | Viewed by 150 | Submission Open

Keywords: skin diseases; ultrasound imaging; optical coherence tomography (OCT) imaging; photoacoustic imaging; reflectance confocal microscopy (RCM) imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Frontier Exploration of Multimodal Imaging in Cardiac Rheumatic and Immune Diseases

edited by

Sophie Mavrogeni

submission deadline 31 Jan 2026 | Viewed by 147 | Submission Open

Keywords: myopericarditis; valvular heart disease; coronary artery disease; vasculitis vascular stenosis; vascular aneurysm; reynard phenomenon

Advances in the Diagnosis and Management of Sports Injuries

edited by

Ki-Mo Jang

submission deadline 31 Jan 2026 | Viewed by 143 | Submission Open

Keywords: sports injury; sports medicine; diagnosis; treatment; surgery; rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 135 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis and Management of Morbid Obesity

edited by Justyna Domienik-Karłowicz

submission deadline 31 Jan 2026 | Viewed by 128 | Submission Open

Keywords: morbid obesity; obesity diagnosis; body composition analysis; visceral adiposity; metabolic syndrome; biomarkers in obesity; genetic predisposition; comorbidity assessment; imaging techniques; risk stratification

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Management, and Prognosis of Liver Disease and Its Syndromes, Second Edition

edited by

Chien Hao Huang

submission deadline 31 Jan 2026 | Viewed by 124 | Submission Open

Keywords: acute liver disease; chronic liver disease; viral hepatitis; liver cirrhosis; non-alcoholic steatohepatitis (NASH); diagnosis; treatment; prognosis score

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Involvement in Connective Tissue Disease: Advances in Diagnosis and Management

edited by Laura Groșeanu

submission deadline 31 Jan 2026 | Viewed by 121 | Submission Open

Keywords: interstitial lung disease; connective tissue disease; complication; etiology; genetic risks; epigenetic changes; dysregulated immunity; CT patterns; mechanisms; screening; assessing; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Role of Magnetic Resonance Imaging in Obesity and Diabetes: 2nd Edition

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 118 | Submission Open

Keywords: magnetic resonance imaging (MRI); obesity and diabetes; diabetic foot complications; brain atrophy; diabetic kidney disease (DKD); functional MRI; non-invasive imaging; early diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Insights into the Diagnosis of Pediatric Cholestasis

edited by Paola Francalanci

submission deadline 31 Jan 2026 | Viewed by 112 | Submission Open

Keywords: extrahepatic cholestasis; intrahepatic cholestasis; biliary atresia; genetic liver disease; inborn errors of metabolism; jaundice; monogenic liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis of Peripheral Vascular Diseases

edited by Micaela Iantorno

submission deadline 31 Jan 2026 | Viewed by 91 | Submission Open

Keywords: peripheral vascular disease; limb; CT angiography; MR angiography; ankle– brachial index; blood flow

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Trends in Ultrasound Imaging

edited by

Ştefan Cristian Vesa

and

Ingrid Andrada Vasilache

submission deadline 15 Feb 2026 | Viewed by 515 | Submission Open

Keywords: ultrasound; imaging; diagnostics; artificial intelligence; elastography; contrast-enhanced ultrasound; radiomics; 3D ultrasound; point-of-care ultrasound; interventional imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Acute Kidney Injury and Chronic Kidney Disease: From Pathogenesis to Diagnostics

edited by

Dimitris Kounatidis

and

Natalia G. Vallianou

submission deadline 28 Feb 2026 | 3 articles | Viewed by 13720 | Submission Open

Keywords: acute kidney injury (AKI); chronic kidney disease (CKD); pathogenesis; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Oral and Maxillofacial Disease: 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 28 Feb 2026 | 8 articles | Viewed by 10246 | Submission Open

Keywords: maxillofacial disease; oral disease; biomarkers; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Diagnostic and Interventional Radiology

edited by

Serena Carriero

submission deadline 28 Feb 2026 | 6 articles | Viewed by 9181 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; image-guided therapy; AI; minimally invasive procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Maternal–Fetal and Neonatal Diagnostics

edited by Elisa Bevilacqua

submission deadline 28 Feb 2026 | 3 articles | Viewed by 9102 | Submission Open

Keywords: high risk pregnancy; twin pregnancy; maternal– fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Otolaryngology 2025

edited by

Rong-San Jiang

submission deadline 28 Feb 2026 | 4 articles | Viewed by 8976 | Submission Open

Keywords: ear; diagnosis; head and neck; management; nose; otolaryngology; throat

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Contemporary Issues in Maternal-Fetal Medicine

edited by

Themistoklis Dagklis

and

Ioannis Tsakiridis

submission deadline 28 Feb 2026 | 5 articles | Viewed by 8726 | Submission Open

Keywords: obstetrics; high-risk pregnancy; maternal medicine; fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Liquid Chromatography–Mass Spectrometry (LC-MS) in the Clinical Laboratory

edited by

Siddabasave Gowda B. Gowda

submission deadline 28 Feb 2026 | 5 articles | Viewed by 7667 | Submission Open

Keywords: LC-MS; clinical diagnostics; biomarker discovery; metabolomics; lipidomics; clinical samples; method validation; precision medicine; analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Colorectal Lesions

edited by Andrei Chitul

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7444 | Submission Open

Keywords: colorectal lesions; diagnostic modalities; imaging techniques; machine learning; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Artificial Intelligence in Gastrointestinal Diseases

edited by Dimitra D. Dionysiou and Ioannis Gallos

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6975 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; biomarkers; screening/diagnosis; personalized medicine; treatment outcome; pathogenesis; risk management

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Echocardiography, 2nd Edition

edited by

Giulia Elena Mandoli

submission deadline 28 Feb 2026 | 6 articles | Viewed by 6967 | Submission Open

Keywords: standard echocardiography; speckle tracking echocardiography; strain; myocardial deformation; 3D echocardiography; valvular reconstruction; differential diagnosis; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Molecular Pathology and Imaging for Precision Diagnosis and Treatment of Tumors

edited by

Maurizio Martini

submission deadline 28 Feb 2026 | 6 articles | Viewed by 6807 | Submission Open

Keywords: molecular pathology; molecular imaging; precision oncology; biomarkers; digital pathology; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Computed Tomography Imaging in Medical Diagnosis, 2nd Edition

edited by

Fabio Sandomenico

submission deadline 28 Feb 2026 | 4 articles | Viewed by 6248 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

Explainable Machine Learning in Clinical Diagnostics

edited by

Kai-Chih Pai

submission deadline 28 Feb 2026 | 5 articles | Viewed by 5903 | Submission Open

Keywords: interpretable machine learning (IML); explainable machine learning; clinical medicine; knowledge integration; global/local explanations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI in Dermatology

edited by Jonathan Shapiro

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5424 | Submission Open

Keywords: teledermatology; artificial intelligence; AI algorithms; natural language processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Technological Advances in Oral and Maxillofacial Surgery for Diagnosis

edited by

Maria Giulia Cristofaro

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5168 | Submission Open

Keywords: oral and maxillofacial surgery; oral cancers; maxillofacial trauma; surgical and informatics technology; intraoperative navigation; robotic surgery; oral and maxillofacial surgery reconstruction; nanotechnologies; DNA sequencing

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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