New Perspectives in Cosmetics and Dermatology: Mechanisms and Therapies

A special issue of Cosmetics (ISSN 2079-9284). This special issue belongs to the section "Cosmetic Dermatology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1360

Special Issue Editor

Special Issue Information

Dear Colleagues,

Cosmetics have significantly evolved in recent years, expanding beyond aesthetics into fields of scientific and dermatological relevance. In this Special Issue, we will explore the role of cosmetics from various perspectives: as a science that studies the biological mechanisms of the skin, as a complementary tool in clinical dermatology, and as an adjuvant therapy for treating various skin conditions.

Additionally, we will address the growing influence of cosmetics in a "new era", where advances in molecular research, personalised treatments, and integration with dermatological therapies offer new possibilities to enhance skin health and well-being. We invite scientists, dermatologists, and researchers to share their experiences, clinical studies, and reviews in this constantly evolving field.

We aim to develop an issue that will become a reference in this fascinating intersection between cosmetics and dermatological science.

Dr. Montserrat Fernández-Guarino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cosmetics
  • immunoderamtology
  • cutaneous lymphoma
  • cutaneous drug reac-tion
  • erythroderma
  • psoriasis
  • atopic dermatitis
  • eczematous reactions

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Published Papers (1 paper)

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Research

16 pages, 5324 KiB  
Article
RNA Sequencing Reveals Effects of a New Complex Bath Additive on Cultured Cells
by Norihiro Otani, Kieu D. M. Nguyen, Jiawei Wan, Yasuharu Kanki and Takehito Sugasawa
Cosmetics 2025, 12(3), 98; https://doi.org/10.3390/cosmetics12030098 - 13 May 2025
Viewed by 1058
Abstract
In recent years, bath additives developed to enhance the physiological benefits of bathing have become a popular part of self-care routines. However, there has been little investigation of the biological effects of these additives, especially in terms of their impact on gene expression. [...] Read more.
In recent years, bath additives developed to enhance the physiological benefits of bathing have become a popular part of self-care routines. However, there has been little investigation of the biological effects of these additives, especially in terms of their impact on gene expression. To bridge this research gap, this study was implemented to reveal the effects of a newly developed complex bath additive, Karada Totonou ProBath (KTPB), on gene expression, using RNA sequencing (RNA-seq). Two human skin-derived cell lines (keratinocytes and fibroblasts) were treated with KTPB at a final concentration of 100 μg/mL, and RNA extracted between 15 and 240 min after treatment was subjected to RNA-seq analysis. The results showed that KTPB induced significant changes in the expression of over 80 genes in both cell lines. In particular, the expression levels of genes encoding Early Growth Response Protein 1 and Hyaluronic Acid Synthases increased over time following the treatment. Enrichment analysis showed the upregulation of pathways associated with cell activation in both cell types, with no evidence of KTPB-related cytotoxicity. The findings suggest that KTPB activates the metabolism of skin cells through hormesis without inducing toxicity. Our results provide new insights promoting future research in this field. Full article
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