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Special Issue "Cells in Cardiovascular Disease"
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (30 April 2020) | Viewed by 87995
Special Issue Editors
2. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Roselló 161 6p, 08036 Barcelona, Spain
Interests: hemostasis; vitamin K-dependent proteins; GAS6 and ProS; receptor tyrosine kinases; cardiovascular pathology; liver diseases
Special Issues, Collections and Topics in MDPI journals
Interests: cardiovascular disease; abdominal aortic aneurysm; atherosclerosis; nuclear receptors
Special Issue Information
Advances in the molecular characterization of tissues have provided unique insights into the response to injury and the adaptation of cells to disease processes. In this context, cardiovascular research has witnessed how the role of several cell types that make up the heart, vessels, and blood was unveiled in recent years to a minute detail. This has allowed revealing the plasticity of certain cell types, new cellular interactions and interconnections, as well as surprising cellular functions in certain pathophysiological settings.
The endothelium is crucial in regulating cellular traffic and plays an essential role in many cardiovascular diseases (CVD). Endothelial damage is paramount for platelet and coagulation activation, the ultimate cause of thrombosis, leading to myocardial infarction. The concept of atherosclerosis—the primary cause of coronary artery disease, stroke, and peripheral vascular disease—as a chronic inflammatory disease was recognized early. At present, the essential role of inflammatory and immune cells in the development and progression of many CVDs, from plaque progression and vulnerability to cardiac remodeling, aortic aneurysm, valvular disease or atrial fibrillation, is widely accepted. At the same time, the interplay of resident cells, as cardiomyocytes, smooth muscle cells, and fibroblasts, with blood cells and blood-derived cellular components in CVD, have been better understood and found critical for tissue healing and regeneration.
The present Special Issue aims to summarize some of the newest advances in cellular biology in CVD. We aim to highlight the key involvement of resident and infiltrated cells in the pathophysiology of CVD, including reviews focused on specific cell types. On the other hand, we want to examine the cellular mechanisms that lie behind the processes of repair and recovery of functionality after tissue damage in the context of CVD.
Dr. Pablo García De Frutos
Prof. José Martínez-González
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cardiovascular system
- cardiovascular disease
- cardiac remodeling
- cardiac hypertrophy
- cardiac regeneration
- heart failure
- atrial fibrillation
- vascular smooth muscle cells
- regulatory T cells