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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Robotic and Laparoscopic Surgery in Colorectal Cancer: Current Trends and Future Perspectives

edited by

Felix Aigner

, Quentin Denost and Barbara Noiret

submission deadline 30 Aug 2026 | Viewed by 97 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; colorectal cancer; minimally invasive surgery; comparative outcomes (perioperative; oncologic; functional); conversion rates; open surgery; learning curve and surgical training; cost‐effectiveness and health economics; technological innovations (e.g.; AI; imaging; instrumentation); quality of life and long‐term patient‐reported outcomes

(This special issue belongs to the Section Cancer Therapy)

Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)

edited by

Ching-Sheng Hsu

Po-Heng Chuang

and I-Cheng Lee

submission deadline 30 Aug 2026 | Viewed by 81 | Submission Open

Keywords: tumor suppressor; targeted therapy; hepatocellular carcinoma

(This special issue belongs to the Section Tumor Microenvironment)

Neoantigen Vaccines for Cancer Therapy

edited by Takashi Morisaki

submission deadline 30 Aug 2026 | Viewed by 71 | Submission Open

Keywords: neoantigens; vaccine; dendritic cells; cancer; immunotherapy; priming; CTL; helper T cells

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Gastrointestinal Malignancy: Epidemiology and Risk Factors

edited by Patrick Okolo and Chengu Niu

submission deadline 31 Aug 2026 | 8 articles | Viewed by 31323 | Submission Open

Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes

edited by Petros I. Bangeas and Vasileios N. Papadopoulos

submission deadline 31 Aug 2026 | 4 articles | Viewed by 16975 | Submission Open

Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery

(This special issue belongs to the Section Cancer Therapy)

Advancements in “Cancer Biomarkers” for 2025–2026

edited by

Maxim V. Berezovski

submission deadline 31 Aug 2026 | 10 articles | Viewed by 14964 | Submission Open

Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis

(This special issue belongs to the Section Cancer Biomarkers)

Feature Review Paper Special Issue in Section Molecular Cancer Biology

edited by

Donat Kögel

submission deadline 31 Aug 2026 | 3 articles | Viewed by 8986 | Submission Open

Keywords: molecular biology; cell biology; cancer; tumor; cancer cell

(This special issue belongs to the Section Molecular Cancer Biology)

Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer

edited by

Mingyao Chen

and

Kuang-Chun Hu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4609 | Submission Open

Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis

edited by

Ming Tan

and

Evgeniy V. Denisov

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4145 | Submission Open

Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition

edited by

Francesca Colombo

and Frullanti Elisa

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2756 | Submission Open

Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics

(This special issue belongs to the Section Cancer Therapy)

CAR T-Cell Therapy and Multiple Myeloma

edited by Jo Caers

submission deadline 31 Aug 2026 | 1 articles | Viewed by 695 | Submission Open

Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Emergencies in Gastrointestinal Surgical Oncology

edited by

Fausto Rosa

Carlo Alberto Schena

and

Nicola De'Angelis

submission deadline 31 Aug 2026 | Viewed by 554 | Submission Open

Keywords: surgical oncology; emergencies; emergency surgery; acute care surgery; palliation; futility in surgery

(This special issue belongs to the Section Clinical Research of Cancer)

New Advances and Approaches in Thyroid Cancer

edited by

Beatriz Febrero

and José Manuel Rodríguez

submission deadline 31 Aug 2026 | 1 articles | Viewed by 534 | Submission Open

Keywords: thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; poorly differentiated thyroid tumours; novel approaches; prognostic biomarkers; risk stratification

(This special issue belongs to the Section Cancer Therapy)

Hereditary Cancer: State of the Art

edited by Joanne Ngeow, Jianbang Chiang and

Rashid N. Lui

submission deadline 31 Aug 2026 | Viewed by 192 | Submission Open

Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance

(This special issue belongs to the Section Cancer Pathophysiology)

Hypoxia-Targeting Strategies to Improve Cancer Therapy Outcomes

edited by Roben Gieling and Ayse Latif

submission deadline 31 Aug 2026 | Viewed by 124 | Submission Open

Keywords: tumor hypoxia; cancer therapy resistance; hypoxia-targeted therapy; hypoxia-inducible factors (HIFs); hypoxia-activated prodrugs; oxygen-modifying agents; combination therapy; precision drug delivery; tumor microenvironment; translational cancer research

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment in Cancer Therapies: Supportive or Hostile?

edited by

Constantin N. Baxevanis

submission deadline 31 Aug 2026 | Viewed by 109 | Submission Open

Keywords: tumor microenvironment; protumor effects; antitumor effects; immune cells; stromal cells; extracellular matrix; cancer therapies

(This special issue belongs to the Section Tumor Microenvironment)

Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact

edited by Jun-Pyo Myong

submission deadline 31 Aug 2026 | Viewed by 94 | Submission Open

Keywords: occupational exposure; chemical carcinogens; risk assessment; epidemiology; biomarkers; exposure assessment; preventive strategies; workplace safety; occupational health; regulatory measures

(This special issue belongs to the Section Infectious Agents and Cancer)

Acute Myeloid Leukemia in Adults (2nd Edition)

edited by

Theodoros Karantanos

submission deadline 31 Aug 2026 | Viewed by 92 | Submission Open

Keywords: acute myeloid leukemia; molecular biology; treatment landscape; resistance mechanisms

(This special issue belongs to the Section Clinical Research of Cancer)

CAR T Cell Therapy in Cancer: Progress and Challenges Across Solid and Hematologic Malignancies

edited by John F. Marshall and Lauren C. Cutmore

submission deadline 31 Aug 2026 | Viewed by 88 | Submission Open

Keywords: CAR-T cell therapy; adoptive cell therapy; immunotherapy; antigen escape; solid tumor; hematologic malignancies

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Unseen Burden: Incidence and Outcomes of Infections in Leukemia

edited by

Elisa Buzzatti

and

Maria Ilaria Del Principe

submission deadline 31 Aug 2026 | Viewed by 88 | Submission Open

Keywords: infection management; infectious risk; antimicrobial therapy; antimicrobial prophylaxis

(This special issue belongs to the Section Infectious Agents and Cancer)

Clinical Treatment and Outcomes of Gastrointestinal Cancer

edited by Mary Linton Peters

submission deadline 31 Aug 2026 | Viewed by 87 | Submission Open

Keywords: gastrointestinal cancer; ctDNA; chemotherapy; immunotherapy; financial toxicity; clinical trial participation

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in the Early Diagnosis and Treatment of Gastric Cancer (2nd Edition)

edited by Sharona B. Ross

submission deadline 31 Aug 2026 | Viewed by 76 | Submission Open

Keywords: gastric cancer; tumor resection; liver tumors

(This special issue belongs to the Section Cancer Therapy)

Early Detection and Strategies for Overcoming Therapy Resistance in Lung Cancer and Mesothelioma

edited by

Katalin Dobra

submission deadline 31 Aug 2026 | Viewed by 62 | Submission Open

Keywords: lung cancer; mesothelioma; screening; biomarker; molecular diagnostics; resistance

(This special issue belongs to the Section Cancer Therapy)

Wnt Signaling Pathway in Cancer Immunotherapy

edited by

Yong-Mi Kim

and

Michael Kahn

submission deadline 31 Aug 2026 | Viewed by 56 | Submission Open

Keywords: Wnt signaling; immunotherapy; immune cells; macrophages; T-cell; CART cells; stromal cells; tumor microenvireonment; cancers; cancer stem cells

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in the Multimodal Management of Pancreatic Ductal Adenocarcinoma

edited by

Olav F. Dajani

Knut Jørgen Labori

and

Arne Westgaard

submission deadline 31 Aug 2026 | Viewed by 50 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); multimodal approach; systemic therapy; radiotherapy; targeted strategies; neoadjuvant therapy; adjuvant therapy

(This special issue belongs to the Section Cancer Therapy)

Cancer Therapy-Related Adverse Events (2nd Edition)

edited by

Yinghong Wang

and Pauline Funchain

submission deadline 1 Sep 2026 | 2 articles | Viewed by 4725 | Submission Open

Keywords: cancer; cancer therapy; toxicities; adverse events

(This special issue belongs to the Section Cancer Therapy)

The Role of Minimally Invasive and Minimally Radical Surgery in Cervical and Endometrial Cancer

edited by

Raj Naik

Marie Plante

, Christophe Pomel,

Roberto Tozzi

and Gwénaël Ferron

submission deadline 1 Sep 2026 | Viewed by 119 | Submission Open

Keywords: cervical cancer; endometrial cancer; laparoscopic surgery; minimally invasive surgery; surgical oncology; fertility-sparing surgery; non-radical surgery; conservative surgery

(This special issue belongs to the Section Cancer Therapy)

Prostatectomy Today: Surgical Advances in Prostate Cancer Management

edited by

Ettore Mearini

submission deadline 1 Sep 2026 | Viewed by 73 | Submission Open

Keywords: prostate cancer; robot-assisted radical prostatectomy; robotic system; perioperative outcomes; sexual function; urinary continence; oncological outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology

edited by

Helena Batatinha

and Geovana Leite

submission deadline 10 Sep 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Interventional Oncologic Therapies

edited by Edward W. Lee and

Dong Il Gwon

submission deadline 15 Sep 2026 | 3 articles | Viewed by 10574 | Submission Open

(This special issue belongs to the Section Cancer Therapy)

First-Line Therapy in Thoracic Oncology

edited by Antonio D'Andrilli and

Giulio Maurizi

submission deadline 15 Sep 2026 | 3 articles | Viewed by 3286 | Submission Open

Keywords: thoracic oncology; lung cancer; thymoma; mediastinal tumors

(This special issue belongs to the Section Cancer Therapy)

The Clinical, Technological, and Scientific Progress of Boron Neutron Capture Therapy

edited by

Shinji Kawabata

submission deadline 15 Sep 2026 | Viewed by 671 | Submission Open

Keywords: boron neutron capture therapy (BNCT); neutron capture therapy (NCT); accelerator-based neutron source; neutron dosimetry; boron drug development; alternative capture agents; radiobiological effects; radiation oncology; interdisciplinary research; clinical translation

(This special issue belongs to the Section Cancer Therapy)

Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer

edited by

Aiham Qdaisat

and

Sai-Ching Jim Yeung

submission deadline 15 Sep 2026 | Viewed by 88 | Submission Open

Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Breast Cancer: Immune Response, Immune Microenvironment, and Immunotherapy

edited by

Ravindra Deshpande

and

Ann Richmond

submission deadline 15 Sep 2026 | Viewed by 76 | Submission Open

Keywords: breast cancer; immune response; tumor immune microenvironment; immunotherapy resistance; intrinsic and extrinsic mechanisms; immune checkpoint inhibitors; T-cell dysfunction; cytokines; cancer vaccines; tumor immunosuppression

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes

edited by

Manali I. Patel

submission deadline 15 Sep 2026 | Viewed by 54 | Submission Open

Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care

Advances in Breast Conservation Therapy: A Global Perspective

edited by Tristen S. Park

submission deadline 15 Sep 2026 | Viewed by 45 | Submission Open

Keywords: breast conservation therapy; survival; breast cancer

(This special issue belongs to the Section Cancer Therapy)

T Cells in Hematologic Malignancies: Biology, Microenvironment, and Therapeutic Advances

edited by

Maria Velegraki, MD, PhD

submission deadline 16 Sep 2026 | Viewed by 98 | Submission Open

Keywords: T cells; hematologic malignancies; CAR-T therapy; bispecific T cell engagers; tumor immune microenvironment; T cell dysfunction and exhaustion; leukemia; lymphoma; and myeloma; acute myeloid leukemia and MDS; immunotherapy resistance and relapse; next-generation cellular therapies

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Management of Pancreatic Cancer: 2nd Edition

edited by

Traian Dumitrascu

submission deadline 18 Sep 2026 | Viewed by 38 | Submission Open

Keywords: pancreatic cancer; adenocarcinoma; neuroendocrine carcinomas; molecular and pathological aspects; diagnosis; medical treatment; palliative therapy

Advances in Salivary Gland Carcinoma: 2nd Edition

edited by

Giulio Cantù

submission deadline 20 Sep 2026 | 2 articles | Viewed by 6153 | Submission Open

Keywords: salivary gland tumors; head and neck cancer; facial nerve preservation; facial nerve reconstruction; facial nerve sacrifice; parotid cancer; parotidectomy; prognostic factors

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Molecular Pathology Insights in Thyroid Cancer

edited by Salma Khan

submission deadline 20 Sep 2026 | Viewed by 285 | Submission Open

Keywords: non-coding RNAs; epigenetics; biomarkers; BRAF mutations; RAS mutations; targeted therapy; precision medicine; genomic profiling; tumor heterogeneity; therapeutic resistance

(This special issue belongs to the Section Cancer Pathophysiology)

Clinical Outcomes in Upper GI Cancers

edited by

Yoshiaki Shoji

submission deadline 20 Sep 2026 | Viewed by 75 | Submission Open

Keywords: esophageal cancer; gastric cancer; esophagogastric junction cancer; surgery; endoscopy; chemotherapy; immuno-therapy; molecural target therapy; biomarker

(This special issue belongs to the Section Clinical Research of Cancer)

Targeting the Vulnerabilities of Oncogene Activation (Second Edition)

edited by

Jack L. Arbiser

submission deadline 25 Sep 2026 | Viewed by 247 | Submission Open

Keywords: tumorigenesis; tumor-suppressor genes; oncogene; target

(This special issue belongs to the Section Methods and Technologies Development)

Role of Iron Metabolism in Tumor Progression

edited by

Xiang Xue

submission deadline 25 Sep 2026 | Viewed by 21 | Submission Open

Keywords: iron metabolism; ferroptosis; tumor microenvironment; oxidative stress; iron chelation therapy; ferritin; transferrin receptor; cancer metabolism; redox homeostasis; therapeutic targeting

(This special issue belongs to the Section Molecular Cancer Biology)

Advances and Challenges in the Diagnosis and Treatment of Urological Malignancies (2nd Edition)

edited by

Bartosz Małkiewicz

Jakub Dobruch

and

Łukasz Nowak

submission deadline 30 Sep 2026 | 7 articles | Viewed by 13737 | Submission Open

Keywords: prostate cancer; bladder cancer; upper urinary tract tumors; kidney cancer; testicular tumors; molecular markers; lymph node metastasis; diagnosis; radical treatment; systemic treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Neurosurgery Research on Brain Tumors: A Focus on Gliomas and Other Intra-Axial Brain Tumors

edited by

Andrea Di Cristofori

, Carlo Giussani, Cesare Zoia and Daniele Bongetta

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4817 | Submission Open

Keywords: neurosurgery; glioma; neuropsychology; neurophysiological monitoring; intraoperative imaging (including iMRI and iOUS); neuroanatomy; outcome; prognosis and quality of life; MRI (including fMRI; MR spectroscopy; perfusion and DTI tractography); radiogenomics; multimodal treatments; druggable targets; artificial intelligence and deep learning

(This special issue belongs to the Section Clinical Research of Cancer)

Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma

edited by

Norihiro Imai

and

Dongming Liu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3497 | Submission Open

Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent

(This special issue belongs to the Section Cancer Biomarkers)

Tumor Microenvironment Dynamics in Hepatocellular Carcinoma

edited by Joseph Franses and Adam Burgoyne

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2258 | Submission Open

Keywords: liver cancer; immune therapy; biomarkers; treatment resistance; cellular interactions

(This special issue belongs to the Section Tumor Microenvironment)

Novel Advancements in Prostate Cancer Surgery: Indications and Techniques

edited by Valerio Santarelli and

Alessandro Sciarra

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1367 | Submission Open

Keywords: radical prostatectomy; prostate cancer; technology; minimally invasive surgery

(This special issue belongs to the Section Cancer Therapy)

Multimodal Artificial Intelligence/Machine Learning Applications in Malignant Tumors: Diagnosis, Prognosis, and Management

edited by

Sam Payabvash

and Stefan Haider

submission deadline 30 Sep 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: machine learning; radiomics; cancer imaging; malignancy; survival

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Targeting RNA to Improve Cancer Precision Medicine

edited by

Gabriella Misso

, Anna Grimaldi and Chiara Tammaro

submission deadline 30 Sep 2026 | Viewed by 508 | Submission Open

Keywords: cancer; RNA therapy; RNA delivery; RNA; miRNA; mRNA; siRNA; oligonucleotides; aptamers; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 1001-1050 on page 21 of 24.

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