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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thermal Ablation in the Management for Colorectal Liver Metastases: 2nd Edition

edited by

Martijn Meijerink

and

Robbert S. S. Puijk

submission deadline 15 Jul 2026 | Viewed by 14 | Submission Open

Keywords: image-guided therapies; colorectal liver metastases (CRLMs); thermal ablation; (non-)thermal and radiation-related treatment; interventional and radiation oncology

(This special issue belongs to the Section Cancer Metastasis)

Robotic and Laparoscopic Techniques for Urologic Cancers: Innovations in Resection and Reconstruction

edited by

Tobias Klatte

submission deadline 15 Jul 2026 | Viewed by 8 | Submission Open

Keywords: robot-assisted surgery; surgical robotics; minimally invasive surgery; artificial intelligence; complications; prognostic and predictive factors; planning; perioperative care

(This special issue belongs to the Section Methods and Technologies Development)

Myelodysplastic Neoplasms (MDS) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy

edited by

Ling Zhang

, David Sallman and Deniz Peker

submission deadline 15 Jul 2026 | Submission Open

Keywords: myelodysplastic syndromes/myelodysplastic neoplasms (MDS); myelodysplastic/myeloproliferative neoplasm; chronic myelomonocytic leukemia (CMML); diagnosis; mutations; IPSS-R; IPSS-M; hypomethylation agents; targeted therapy; hematopoietic stem cell transplant (HSCT)

(This special issue belongs to the Section Molecular Cancer Biology)

Personalizing Head and Neck Cancer Care

edited by

Inge Wegner

and

G. B. Halmos

submission deadline 17 Jul 2026 | Viewed by 30 | Submission Open

Keywords: head and neck cancer; personalized treatment; targeted therapy; prehabilitation; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Skin Cancer: Epidemiology, Management and New Therapies

edited by

Gerardo Cazzato

and Francesco Fortarezza

submission deadline 20 Jul 2026 | 3 articles | Viewed by 4697 | Submission Open

Keywords: skin cancer; melanoma; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; adnexal tumor; metastatic cutaneous neoplasms; epidemiology; management; therapy

(This special issue belongs to the Section Cancer Therapy)

Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1599 | Submission Open

Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers

(This special issue belongs to the Section Cancer Therapy)

HIV-Associated Lymphoid Neoplasms (2nd Edition)

edited by

José-Tomás Navarro

and

Kai Hübel

submission deadline 20 Jul 2026 | Viewed by 90 | Submission Open

Keywords: B-cell lymphoma; HIV; AIDS; Epstein– Barr virus; epidemiology; pathogenesis; prognosis

(This special issue belongs to the Section Infectious Agents and Cancer)

Breaking the Cycle: CDK4/6 Inhibitors Take on Cancers

edited by

Navid Sobhani

submission deadline 20 Jul 2026 | Submission Open

Keywords: CDK4/6 inhibitors; p16; targeted therapy; tumor microenvironment

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Diagnostic and Therapeutic Approaches in Urologic Oncology

edited by

Whi-An Kwon

submission deadline 21 Jul 2026 | Viewed by 78 | Submission Open

Keywords: urologic oncology; liquid biopsy; immunotherapy; artificial intelligence; targeted therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Current Advances in Surgical and Systemic Treatment of Breast Cancer

edited by

Kwok-Leung Cheung

and

Srinivasan Madhusudan

submission deadline 23 Jul 2026 | Viewed by 61 | Submission Open

Keywords: breast cancer; breast surgery; oncoplastic surgery; systemic therapy; biomarkers; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Exosomes and Cancer Biomarkers

edited by

Nathan Wall

submission deadline 24 Jul 2026 | Viewed by 358 | Submission Open

Keywords: exosomes; cancer biomarkers; liquid biopsy; tumor microenvironment; molecular diagnosis

(This special issue belongs to the Section Cancer Biomarkers)

Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and Senthamizhchelvan Srinivasan

submission deadline 25 Jul 2026 | Viewed by 68 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Ovarian Cancer: Pathogenesis, Molecular Mechanism and Opportunities for Interventions

edited by

Apriliana Kartikasari

submission deadline 30 Jul 2026 | 1 articles | Viewed by 1260 | Submission Open

Keywords: ovarian cancer; pathogenesis; therapy; biomarkers; molecular

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Precision Medicine and Targeted Therapies in Neuroblastoma

edited by

Nilay Shah

submission deadline 30 Jul 2026 | 1 articles | Viewed by 1130 | Submission Open

Keywords: pediatric oncology; solid tumors; targeted therapies; biomarkers of response; novel combination therapies; tumor microenvironment; integrative diagnostics; theranostics; telomere maintenance mechanisms; neuroblastoma

(This special issue belongs to the Section Clinical Research of Cancer)

Cutting-Edge Nanomedicine Advancements in Cancer Disease

edited by

Ana Isabel Torres-Suárez

and

Ana Isabel Fraguas-Sánchez

submission deadline 30 Jul 2026 | Viewed by 294 | Submission Open

Keywords: active targeting; breast cancer; drug delivery; liposomes; lung cancer; metallic nanoparticles; polymeric nanoparticles; theragnostic

(This special issue belongs to the Section Methods and Technologies Development)

Flow Cytometry and Molecular Studies in Hematological Malignancies

edited by Kirill A. Lyapichev

submission deadline 30 Jul 2026 | Viewed by 144 | Submission Open

Keywords: flow cytometry; molecular studies; hematological neoplasms; lymphoma; leukemia

(This special issue belongs to the Section Molecular Cancer Biology)

Machine Learning and Artificial Intelligence in Cancer Diagnostic and Monitoring

edited by

Junfeng Wang

submission deadline 30 Jul 2026 | Viewed by 102 | Submission Open

Keywords: machine learning; artificial intelligence; implementation; fairness; uncertainty

(This special issue belongs to the Section Methods and Technologies Development)

Multidisciplinary Approach to Bladder Cancer Treatment and Care

edited by Bente Thoft Jensen and

Susanne Vahr Lauridsen

submission deadline 30 Jul 2026 | Viewed by 69 | Submission Open

Keywords: non-muscle-invasive bladder cancer; muscle-invasive bladder cancer; health-related quality of life; nutrition; prehabilitation; sexual health; nursing leadership; implementation; new technologies

(This special issue belongs to the Section Cancer Therapy)

Resection and Reconstruction for Breast Cancer

edited by Radoslaw Tarkowski and

Gilles Houvenaeghel

submission deadline 30 Jul 2026 | Viewed by 61 | Submission Open

Keywords: oncoplastic breast surgery; breast reconstruction; breast cancer

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Surgical Management of Ovarian Cancer

edited by Lina Salman

submission deadline 30 Jul 2026 | Viewed by 46 | Submission Open

Keywords: ovarian cancer; surgical management; complications; HIPEC; survival

(This special issue belongs to the Section Clinical Research of Cancer)

Evolving Understanding of the Epidemiology of Thyroid Cancer

edited by

Marco Capezzone

and

Anello Marcello Poma

submission deadline 31 Jul 2026 | 2 articles | Viewed by 5226 | Submission Open

Keywords: thyroid cancer; epidemiology; incidence; time trends; mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Systematic Reviews and Meta-Analyses of Genitourinary Cancers (2nd Edition)

edited by

Giorgio Treglia

and Ursula Maria Vogl

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4745 | Submission Open

Keywords: systematic review; meta-analysis; oncology; genitourinary cancers; diagnosis; therapy

(This special issue belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)

Circulating Tumor Cells (CTCs) and the Implementation of Liquid Biopsy (2nd Edition)

edited by

Dario Marchetti

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2317 | Submission Open

Keywords: liquid biopsy; metastatic biomarkers; CTCs isolation technologies; tumor heterogeneity; clinical CTC applications

(This special issue belongs to the Section Tumor Microenvironment)

Clinical Treatment and Prognosis of Breast Cancer

edited by Roxana Popescu and

Ionut Marcel Cobec

submission deadline 31 Jul 2026 | Viewed by 587 | Submission Open

Keywords: breast cancer; targeted therapy; personalized therapy; alternative approach; tumor biology; gynecologic oncology

(This special issue belongs to the Section Clinical Research of Cancer)

CRISPR in Cancer Biology and Therapy: 2nd Edition

edited by

Shun-Qing Liang

submission deadline 31 Jul 2026 | Viewed by 423 | Submission Open

Keywords: cancer drug resistance; CRISPR screens; CRISPR-related technology; base editing; prime editing; off-target analysis; adeno-associated virus

(This special issue belongs to the Section Methods and Technologies Development)

Hybrid Molecular Imaging Approaches in Cancer: PET/CT, PET/MRI, and Beyond

edited by

Luca Urso

submission deadline 31 Jul 2026 | 1 articles | Viewed by 368 | Submission Open

Keywords: PET/CT; PET/MRI; hybrid molecular imaging; radiomics and artificial intelligence; conventional PET Radiotracers; emerging PET Radiotracers; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Molecular Genomics in Brain Tumors

edited by

Marta Mellai

and

Renzo Boldorini

submission deadline 31 Jul 2026 | Viewed by 340 | Submission Open

Keywords: glioma; signaling pathways; metabolism; microbiota– gut– brain axis; biomarkers; therapeutics; immunotherapy

(This special issue belongs to the Section Cancer Pathophysiology)

Melanoma: Pathology and Translational Research—2nd Edition

edited by

Alessio Giubellino

Carlos Torres-Cabala

and Jose A. Plaza

submission deadline 31 Jul 2026 | Viewed by 276 | Submission Open

Keywords: melanoma; histopathology; dermatopathology; molecular profiling; biomarkers; digital pathology; translational studies; cancer therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Recent Developments on PET-CT in Multiple Myeloma

edited by Carmelo Caldarella

submission deadline 31 Jul 2026 | Viewed by 138 | Submission Open

Keywords: PET/CT; multiple myeloma; novel radiopharmaceuticals; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Novel Insights into Glioblastoma and Brain Metastases (2nd Edition)

edited by

Sanjay K. Srivastava

submission deadline 31 Jul 2026 | Viewed by 85 | Submission Open

Keywords: glioblastoma; brain metastasis; surgery; radiation; chemotherapy; blood– brain barrier; immunotherapy; novel targets; oncogenes; tumor heterogeneity; drug discovery

(This special issue belongs to the Section Cancer Metastasis)

Molecular Mechanisms of Resistance to Cancer Therapies

edited by

Amancio Carnero

and

Rikki A.M. Brown

submission deadline 31 Jul 2026 | Viewed by 85 | Submission Open

Keywords: therapy resistance; cancer heterogeneity; drug resistance mechanisms; targeted therapy resistance; immunotherapy resistance; tumor microenvironment; epigenetic reprogramming; biomarkers of resistance; clonal evolution

(This special issue belongs to the Section Molecular Cancer Biology)

Biologic Advancements in Childhood and Adolescent Cancers: From Disease Mechanisms to Precision Therapies

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 82 | Submission Open

Keywords: pediatric oncology; precision therapies; molecular vulnerabilities; biomarker-driven trials; disease mechanisms

(This special issue belongs to the Section Pediatric Oncology)

Hematopoietic Stem Cells and Cancer Immunotherapy

edited by Harinad B. Maganti

submission deadline 31 Jul 2026 | Viewed by 75 | Submission Open

Keywords: hematopoietic stem cell; transplantation; leukemia; cell biology; CAR-T cell therapies; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Clinical Trials for Hepatobiliary and Pancreatic Cancer Diagnosis and Treatment (2nd Edition)

edited by

Takuji Okusaka

submission deadline 31 Jul 2026 | Viewed by 69 | Submission Open

Keywords: biliary cancer; liver cancer; pancreatic cancer; clinical trial; diagnosis; surgery; neoadjuvant therapy; adjuvant therapy; radiotherapy; chemotherapy; targeted therapy; precision medicine; immunotherapy; biliary and duodenal stent; psycho-oncology; palliative and supportive care

(This special issue belongs to the Section Clinical Research of Cancer)

The Emerging Role of Multiplexed Imaging for Cancer Diagnosis and Therapy (2nd Edition)

edited by

Li Liu

and

Yicheng Ni

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: multiplexed imaging; cancer diagnosis; molecular imaging; novel contrast agents; targeted radionuclide tracers theragnostics; personalized cancer therapy; therapeutic monitoring; imaging biomarkers; clinical translation

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice—2nd Edition

edited by

Dario Bugada

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: perioperative care; cancer anesthesia; analgesia; pain management

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Perioperative and Adjuvant Immunotherapy in Lung Cancer: New Strategies, Biomarkers, Patient Selection and Toxicity Management

edited by

Xabier Mielgo Rubio

Felipe Couñago

and Juan Carlos Trujillo-Reyes

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: non-small-cell lung cancer (NSCLC); immunotherapy; neoadjuvant treatment; adjuvant treatment; perioperatory treatment; chemotherapy; surgery; radiotherapy; toxicity; biomarkers

(This special issue belongs to the Section Tumor Microenvironment)

Tumorigenesis and Tumor Microenvironment—Insights and Interventions (TTMII)

edited by

Renu Wadhwa

Sunil C. Kaul

and

Ajaikumar B. Kunnumakkara

submission deadline 31 Jul 2026 | Viewed by 62 | Submission Open

Keywords: tumorigenesis; tumor microenvironment; intervention; stress biology; aging; mortalin; CARF; ashwagandha; propolis; curcumin; natural compounds

(This special issue belongs to the Section Tumor Microenvironment)

Mechanisms of Therapy Resistance in Cancers—2nd Edition

edited by

Birandra K. Sinha

submission deadline 31 Jul 2026 | Viewed by 60 | Submission Open

Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance

(This special issue belongs to the Section Cancer Drug Development)

Nanomedicine for Cancer Treatment

edited by Youssef Wahib Naguib

submission deadline 31 Jul 2026 | Viewed by 59 | Submission Open

Keywords: cancer nanomedicine; CRISPR/CAS9 nanomedicine; immune checkpoint inhibitors; cancer immunotherapy; targeted therapeutics; targeted nanoparticles; cell-penetrating peptides

(This special issue belongs to the Section Cancer Drug Development)

Decoding the Tumor Microenvironment: Immune Cell–Tumor Interplay in Breast Cancer

edited by Abirami Sivapiragasam and Roberto A. Leon Ferre

submission deadline 31 Jul 2026 | Viewed by 59 | Submission Open

Keywords: tumor microenvironment; breast cancer; immune cell– tumor interaction; immunotherapy; T cells; macrophages; dendritic cells; single-cell transcriptomics; spatial transcriptomics; artificial intelligence; prognostic biomarkers; predictive biomarkers; personalized therapy

(This special issue belongs to the Section Tumor Microenvironment)

Current Applications and Cutting-Edge Innovations in Neuroendoscopy: Where Are We and Where Are We Going?

edited by Giuseppe Roberto Giammalva, Giovanni Tringali and Giuseppe Cinalli

submission deadline 31 Jul 2026 | Viewed by 53 | Submission Open

Keywords: neuroendoscopy; endoventricular surgery; skull base surgery; endoscopic assisted neurosurgery; innovations

(This special issue belongs to the Section Methods and Technologies Development)

Microsatellite Instability in Colorectal Cancer

edited by

Joan Maurel

and Vicente Alonso-Orduña

submission deadline 31 Jul 2026 | Viewed by 52 | Submission Open

Keywords: microsatellite instability; colorectal cancer; immune checkpoint inhibitors; immune signatures

(This special issue belongs to the Section Tumor Microenvironment)

Pheochromocytoma and Paraganglioma: Molecular Insights and Clinical Frontiers

edited by

Ivana Jochmanová

submission deadline 31 Jul 2026 | Viewed by 47 | Submission Open

Keywords: pheochromocytoma and paraganglioma; hereditary cancer syndromes; genetic mutations; genotype– phenotype correlations; functional imaging; molecular diagnostics; biomarkers; precision oncology; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) in Patients with Cancers

edited by Caterina Alati and Martina Pitea

submission deadline 31 Jul 2026 | Viewed by 46 | Submission Open

Keywords: hematopoietic stem cell; hematologic malignancies; transplantation; immunotherapy

(This special issue belongs to the Section Transplant Oncology)

Surgical and Non-Surgical Convergence in Hepatocellular Carcinoma

edited by

Alessandro Vitale

submission deadline 31 Jul 2026 | Viewed by 38 | Submission Open

Keywords: hepatocellular carcinoma; conversion therapy; HCC treatment boundaries; surgical– non-surgical convergence; multidisciplinary HCC management

(This special issue belongs to the Section Cancer Therapy)

Advances in Electroporation-Based Technologies for Cancer Treatment

edited by

Bostjan Markelc

and

Gregor Sersa

submission deadline 31 Jul 2026 | Viewed by 38 | Submission Open

Keywords: electroporation; electrochemotherapy; gene electrotransfer; interleukin-12; DNA vaccination; irreversible electroporation; cancer immunotherapy; tumor ablation

(This special issue belongs to the Section Methods and Technologies Development)

Epigenetics: A New Approach to Cancer Therapy

edited by

Sibaji Sarkar

submission deadline 31 Jul 2026 | Viewed by 37 | Submission Open

Keywords: epigenetics; targets; cancer; tumor; signaling regulation; inhibitors; drugs

(This special issue belongs to the Section Cancer Therapy)

Advances in Dermato-Oncology

edited by Carmen Cantisani

submission deadline 31 Jul 2026 | Viewed by 24 | Submission Open

Keywords: melanoma; line-field confocal optical coherence tomography (LC-OCT); confocal microscopy; dermoscopy; non-melanoma skin cancers; treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

New Trends in Urologic Oncology: Surgical Treatments, Robotics, Biomarkers, Diagnostic Tools, and Innovative Therapies

edited by Alessandro Uleri and

Roberto Contieri

submission deadline 31 Jul 2026 | Viewed by 24 | Submission Open

Keywords: prostate cancer; renal cancer; bladder cancer; UTUC; testicular cancer; penile cancer; biomarkers

(This special issue belongs to the Section Clinical Research of Cancer)

Displaying special issue 1001-1050 on page 21 of 24.

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