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Acute Myeloid Leukemia: The Future Is Bright

This special issue belongs to the section “Tumor Microenvironment“.

Special Issue Information

Dear Colleagues, 

The knowledge regarding acute myeloid leukemia (AML) in adults, adolescents and children is rapidly advancing. The extensive characterization of AML cells is now leading to the introduction of tailored therapy, based on a risk group stratified approach, and targeted therapies. Improvements in monitoring measurable residual disease during treatment allow further tailored therapy, while such monitoring following treatment enables pre-emptive treatment of molecular relapses, with acute promyelocytic leukemia as the stimulating example. Moreover, the arsenal of strikingly effective antileukemic drugs is also rapidly expanding, and novel treatment modalities are on the horizon. Together with the improvements in supportive care, the future is bright for all those involved in the care of patients with AML, whether old or young, whether strong or fragile.

Prof. Dr. Gertjan Kaspers
Dr. Kapil Saxena
Guest Editors

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • risk group classification
  • measurable residual disease
  • molecular characterization
  • FLT3-ITD
  • IDH1/2 mutations
  • FLT3 inhibitors
  • MEK inhibitors
  • gemtuzumab ozogamicin
  • supportive care
  • acute promyelocytic leukemia
  • IDH1/2 inhibitors
  • Allogeneic stem cell transplantation
  • CAR T-cell therapy
  • Immunotherapy

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Cancers - ISSN 2072-6694