Treatments of Uveal Melanoma
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 15 October 2025 | Viewed by 543
Special Issue Editor
Special Issue Information
Dear Colleagues,
Uveal melanoma is the most common intraocular malignancy with a significant patient burden in terms of metastatic potential. Eye-preserving treatments with various forms of radiotherapy are well known but often involve vision-affecting sequelae; new treatments are becoming available to not only enable good tumour control but also retain useful long-term vision. In addition, early prophylactic treatment regimens are becoming more common in reducing the incidence and severity of radiation-related ocular sequelae. The advent of small gauge vitrectomy surgery has also increased the awareness and practise of prognostication, which may influence long-term surveillance. Further advances in systemic treatment for metastatic disease may also be utilised in the future for targeting high-risk prognostically identified individuals. All of this forms the basis of more personalised medicine and targeted therapies for this disease with a previously poor outlook.
The aim of this Special Issue is to emphasise the high-quality research being undertaken into this rare but lethal condition. The scope would cover the early identification of small melanomas, the benefits of early treatments, the advances in visually preserving treatments of the primary tumour and the interventions available to preserve vision in treated patients with ocular side effects. In addition, this would include the use both clinically and economically of prognostication, the need for long-term surveillance, and the influence on metastatic disease. Finally, the Special Issue also examines new advances in the treatment of established metastatic disease and the potential for agents to prevent long-term systemic disease.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Early identification of uveal melanoma;
- New vision preserving treatments for uveal melanoma;
- Treatments for radiation induced ocular sequelae;
- Prognostication;
- Surveillance;
- Treatment of metastatic disease.
I look forward to receiving your contributions.
Dr. Rumana N. Hussain
Guest Editor
Manuscript Submission Information
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Keywords
- uveal melanoma
- radiotherapy
- radiation retinopathy
- liver metastases
- prognostication
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