Vaginal Cancer: From Pathology to Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (15 August 2024) | Viewed by 4141
Special Issue Editor
Special Issue Information
Dear Colleagues,
Primary vaginal carcinoma is one of the rarest neoplasms. Worldwide, about 18,000 new cases are documented each year, which corresponds to one per thousand out of all cancers and 1% of all gynaecological cancers. Expressed differently, just as many women develop vaginal carcinoma as men develop breast cancer. However, about 8000 deaths per year worldwide are attributed to vaginal cancer. This indicates that both morbidity and mortality are not negligible. Like most rare diseases, though, the situation with regard to randomised trials or larger collectives is very poor.
The vaginal intraepithelial neoplasia and vaginal carcinoma are usually associated with HPV infection. Age, inflammatory diseases, immunodeficiency and cigarette smoking have been described as risk factors for this disease complex. Due to the HPV association, vaginal neoplasms are also associated with other neoplasms of the vulva and anal canal, and therapies for these may already have been advanced. Besides radical surgery, radiotherapy is one of the most important pillars of oncological therapy. However, these measures are often associated with serious negative effects on the patient's quality of life and morbidity.
In this Special Issue, you will find recent research on pathological, translational and clinical aspects of vaginal neoplasms. We look forward to receiving original research papers and reviews on these relevant, rare topics for all vaginal precancerous lesions and malignancies, their prognosis and possible treatment options.
Dr. Dirk Michael Forner
Guest Editor
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Keywords
- Vaginal cancer
- Vaginal intrapitelial neoplasia
- epidemiology
- management
- sentinel node
- radiotherapy
- chemoradiation
- recurrent disease
- prevention
- quality of life
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