Molecular Biology of Urological Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 2990
Special Issue Editors
Interests: renal cell carcinoma; immunotherapy; metastatic renal cell carcinoma; urothelial carcinoma, immune-based combination therapies; drug development in GU
Special Issues, Collections and Topics in MDPI journals
Interests: renal cell carcinoma; bladder cancer; prostate cancer; therapy; pathways; experimental model
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The three main urological cancers are prostate, bladder, and kidney cancers. They represent 2.2 million cases and 735,000 deaths per year worldwide. At the metastatic stage, although considerable efforts are made, including the development of immune checkpoint inhibitors, therapies remain too rarely curative. This is mainly due to resistance, either intrinsic or therapy-induced, and heterogeneity, which is particularly strong in kidney and bladder cancers, between patients, and for the same patient at histopathologic, genetic, and molecular levels. Resistance to current therapies is also observed for prostate cancer, for which second-generation hormonotherapy and PARP inhibitors are now used as first-line therapies. There have been substantial advances in cutting-edge molecular profiling approaches, including next-generation sequencing and bioinformatic analysis, which have allowed clinicians and researchers in the field to analyze tumor biology in more detail and stratify patients using factors linked with clinical outcome and response to therapy. Landmark advances have been made in recent years with the arrival of drug conjugates and targeted therapies. These are potential molecular characteristics of these cancers. This Special Issue intends to make an exhaustive inventory of the molecular biology of the main urological cancers, considering both the molecular mechanisms of cancer development and the mechanisms of therapeutic responses and resistances.
Dr. Philippe Barthélémy
Dr. Thierry Massfelder
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- kidney cancer
- prostate cancer
- bladder cancer
- therapies
- cell signaling
- resistance
- gene profiling
- hypoxia
- metabolism
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
