Special Issue "Pathogenesis and Treatment of Neurodegenerative Diseases"
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (20 October 2018)
Assoc. Prof. Dr. Basavaraj S. Balapal
Department of Psychiatry, New York University Langone Medical Center, New York City, New York, USA
Faculty at Columbia University Medical Center, Scientist, Division of Analytical Psychopharmacology, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, USA
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Interests: cannabinoid receptors; synaptic plasticity; learning and memory; developmental disorders; neurodegeneration; drugs of abuse and psychiatric disorders
Increasing evidence suggests that brain disorders are becoming the most dangerous public health problems in modern society. More than 600 disorders affect the nervous system. Irrespective of genetic (familial) or environmental (sporadic) cause, many of these disorders become more progressive with age, including Alzheimer’s disease (AD), Parkinson’s disease (PD), stroke, amyotrophic lateral sclerosis (ALS), and many other intellectual disabilities. Most of these disorders are often accompanying atrophy in the structure and function of the central or peripheral nervous systems. Moreover, accumulating evidence also suggests that late-onset neurological disorders might be due to aberrant neural maturation with epigenetic and pathological changes that are set up at early stages of brain maturation, before the appearance of disease symptoms. Thus, evaluating epigenetic, proteins and pathways that are important in neurodegeneration in the developing, as well as adult, brain, together with the characterization of mechanisms necessary during brain development with relevance to brain aging, are of critical importance. The economic and human costs of these neurodegenerative diseases are expected to increase as the population ages. Understanding the underlying brain mechanisms that are affected by these diseases would help to develop potential therapeutic interventions and will form the basis for novel therapeutic treatments for these neurodegenerative disorders.
The current Special Issue is intended to collect a selected number of articles that establish deeper insight in these topics, which bring both broad scientific and public health impact.
Dr. Balapal S. Basavarajappa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 650 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- neurodegenerative disorders
- drugs of abuse
- environmental toxicants
- cognitive deficits
- learning and memory
- neurodegenerative disorders
- molecular mechanisms
- early brain development
- synaptic plasticity
- intellectual disability