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Special Issue "Genetic and Brain Mechanisms of Addictive Behavior and Neuroadaptation"
Deadline for manuscript submissions: closed (5 November 2019).
Interests: addiction; behavioral genetics; quantitative genetics; behavioral pharmacology; stress; neuroscience; sensitization; reward; aversion
The genome and environment are intertwined in their effects on the trajectory of addictive behavior. Understanding the mechanisms associated with disruptive excessive behaviors, such as alcohol and drug use, gambling, eating, and even gaming, is essential to rational intervention. In addition to genetic sequence variation, which impacts risk for addictive behaviors, transcriptomic research is providing insight into specific genes and gene expression networks involved in risk and response. Furthermore, there is growing evidence that epigenetic factors stably impact the transcriptome and have a role in the development of addictive behaviors. Behavioral genetics methods, advances in genetic engineering, the development of genetic tools for manipulation of brain circuitry, and tools for studying the transcriptional potential of cells are contributing to progress in this area of investigation. However, classical methods, such as electrophysiology, behavioral pharmacology, and brain imaging, remain critical for examining cellular responses, neurocircuitry, and the impact of manipulations tied to mechanistic hypotheses. Collaborative efforts are accelerating progress in the field of addiction research and providing the critical information needed for the development of personalized interventions and treatments.
Original research articles advancing our understanding of the “Genetic and Brain Mechanisms of Addictive Behavior and Neuroadaptation” are solicited for this Special Issue. Critical reviews of the existing literature are also welcome.
Dr. Tamara J. Phillips
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Behavioral genetics
- Quantitative genetics
- Gene–environment interaction