Genetics of Neurodegenerative Diseases: Retrospect and Prospect

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".

Deadline for manuscript submissions: 25 November 2024 | Viewed by 351

Special Issue Editors


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Guest Editor
Laboratory of Medical Biology-Genetics, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
Interests: genetics; neurodegeneration; Parkinson’s disease; Alzheimer’s disease; biomarkers; pharmacogenetics

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Guest Editor
Department of Biomedical Sciences, School of Health Sciences, International Hellenic University, Thessaloniki, Greece
Interests: Alzheimer’s disease; neurodegenerative diseases; clinical neurophysiology; event-related potentials
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Special Issue Information

Dear Colleagues,

Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases characterized by progressive degeneration of specific neuronal populations. Their prevalence increases with age, imposing a significant health, social and economic burden worldwide. NDs are characterized by pathological protein aggregation (e.g., β-amyloid, tau, α-synuclein); however, the exact pathogenic mechanisms are still elusive. Despite intense research, there is currently no effective drug to halt ND progression.

This Special Issue is focused on the role of genetics in NDs. In the era of precision medicine, genetic variations are considered a fundamental factor in disease susceptibility, diagnosis, prediction, patient stratification and individualized therapy. We are particularly interested in original articles, reviews and case reports that provide new insights into the genetic contribution of NDs, aiming to better understand the pathogenesis of NDs, recognize possible pathophysiological overlapping mechanisms and prodromal genetic phenotypes, and identify potential novel therapeutic targets and strategies against these devastating diseases.

Dr. Kallirhoe Kalinderi
Dr. Vasileios T. Papaliagkas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Alzheimer's disease (AD)
  • Parkinson's disease (PD)
  • amyotrophic lateral sclerosis (ALS)
  • multiple sclerosis
  • neurodegeneration
  • protein aggregation
  • therapy
  • pharmacogenetics
  • gene
  • nutrigenomics

Published Papers

This special issue is now open for submission.
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