Computational Intelligence in Structure and Function Prediction and Modeling of Proteins—2nd Edition

Dear Colleagues,

Exploring the functions and structures of proteins is paramount for understanding the molecular mechanisms of life. The analyses and predictions of protein functional residues contribute to the research of protein function. The traditional approaches used to extract information regarding protein structures and functions all rely on biophysical or biochemical-associated technologies. These technologies need expensive experimental instruments, complex experimental procedures, and elaborate human resources. They benefit from the development of bioinformatics, which uses intelligent computing methods to accurately predict protein structure information and functional residues. With the avalanche of hundreds of thousands of unknown proteins, computational intelligence- and artificial intelligence (AI)-associated approaches have significantly advanced our understanding of protein structures and their functions, advancing related applications in diverse fields ranging from protein–drug interactions to drug discovery.

This Special Issue of Biomolecules is dedicated to computational methods and analyses focusing on the identification, elucidation, and analysis of protein function-related factors. We welcome both original articles and surveys that cover state-of-the-art advances in this rapidly developing area. We also encourage the submission of experimental studies that are coupled with computational analysis.

The first edition of this Special Issue was a great success; therefore, we look forward to your contributions to the second edition of this Special Issue

Dr. Jian Zhang
Dr. Bi Zhao
Dr. Haiting Chai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.