High-Density Lipoprotein (HDL): The Role of Reverse Cholesterol Transport in Human Health and Disease – 2nd Edition
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: closed (25 April 2022) | Viewed by 3668
Special Issue Editor
Interests: elucidating the role of HDL and reverse cholesterol transport in atheroprotection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
After the success of the first edition of the Special Issue on “High-Density Lipoprotein (HDL): The Role of Reverse Cholesterol Transport in Human Health and Disease” in 2020, it is our pleasure to announce a new edition on the same topic.
Although high-density lipoprotein (HDL) cholesterol levels continue to be included in cardiovascular risk assessment tools, findings from genetic studies and various pharmacologic interventions have called into question the causal role of HDL cholesterol in atherosclerotic heart disease and the suitability of HDL cholesterol as a treatment target. Recent studies have illuminated the dynamic and complex HDL metabolic pathways defined by lipid transport out of the cell, reverse cholesterol transport (RCT), but directly linked to a myriad of other vascular and nonvascular functions. It has become increasingly clear that HDL metabolism has direct relevance to a number of pathophysiologic processes.
I am pleased to announce this Special Issue, which continues to address how HDL and RCT may impact fundamental biologic processes as well as contribute to pathophysiology across a spectrum of human diseases. A major focus of this issue is to structure our current understanding of HDL and RCT by disease process and to emphasize both the fundamental basic science as well as the relevance to human disease.
Dr. Anand K. Rohatgi
Guest Editor
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Keywords
- high-density lipoprotein (HDL)
- reverse cholesterol transport
- atherosclerosis
- cancer
- renal disease
- dementia
- vascular disease
- therapy
- lifestyle
- macular degeneration
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