Special Issue "The Endocannabinoid System in Health and Disease"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-inspired Molecules".

Deadline for manuscript submissions: closed (31 October 2019).

Special Issue Editors

Dr. Andres Ozaita
E-Mail Website
Guest Editor
Experimental and Health Sciences, University Pompeu Fabra, Barcelona, Spain
Interests: endocannabinoid system; cannabinoid receptor; intellectual disability; intracellular signaling; neurogenesis; cognition; structural plasticity
Dr. Patricia Robledo
E-Mail Website
Guest Editor
Integrative Pharmacology and Systems Neuroscience, IMIM-Hospital del Mar Research Institute, Barcelona, Spain
Interests: endocannabinoid system; serotonin system; animal models of mental disorders; novel biomarkers of psychopathology; olfactory neuroepithelium; schizophrenia; first episode psychosis; cognition

Special Issue Information

Dear Colleagues,

The endocannabinoid system is a relevant homeostatic system in the organism. It was discovered almost 30 years ago while searching for distinct targets of Cannabis sativa plant derivatives. Since then, it has emerged as a crucial neuromodulatory system with specific receptors and endogenous mediators widely distributed at peripheral and central levels during life. In the last decades, researchers have interrogated the interaction of cannabinoid compounds with many physiological systems to understand their therapeutic and recreational effects. In addition, the role of the endocannabinoid system in pathological conditions has also driven important efforts in the search for novel appropriate medicinal targets.

This Special Issue aims to emphasize the diversity of areas in biomedical research where the endocannabinoid system may play important roles from the point of view of pathophysiology and as a promising target for therapeutic intervention. This may include nociception/pain perception, reward system/addiction, metabolism/obesity, epilepsy, cancer, multiple sclerosis, chronic inflammation, psychiatric illnesses, cognitive deregulation, aging, neurodegeneration, and ischemia. We encourage all researchers interested in this topic to present research articles or reviews on these different aspects of the endocannabinoid system. This Special Issue can include state-of-the-art reviews on disorders involving the endocannabinoid system, either from a pathophysiological or from a therapeutic perspective.

Dr. Andres Ozaita
Dr. Patricia Robledo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Endocannabinoid system
  • Cannabis compounds
  • Pain
  • Addiction
  • Obesity
  • Epilepsy
  • Cancer
  • Multiple sclerosis
  • Inflammation
  • Psychiatric
  • illnesses
  • Cognition
  • Aging
  • Neurodegeneration
  • Ischemia

Published Papers

There is no accepted submissions to this special issue at this moment.
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