Maternal-Fetal and Neonatal Medicine

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1775

Special Issue Editor


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Guest Editor
Department of Gynecology, Athens Naval and Veteran Hospital, 11521 Athens, Greece
Interests: minimally invasive gynecology; gynecology; endometriosis; gynecologic malignancies; HIPEC; obstetrics; high risk pregnancies
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Special Issue Information

Dear Colleagues,

Maternal–fetal and neonatal health is determined by biological, environmental, and socioeconomic factors, influencing pregnancy outcomes and newborn survival. This Special Issue, ‘Maternal–Fetal and Neonatal Medicine’, addresses the key determinants, novel diagnostics, and evolving treatment strategies.

Maternal health is affected by prenatal nutrition, infections, chronic diseases, and access to healthcare, while neonatal health is affected by conditions such as prematurity, birth asphyxia, infection, and congenital abnormalities.

Early diagnosis is the key in neonatal care. Prenatal imaging (ultrasound, MRI), genetic testing, APGAR scoring, blood gas analysis, and metabolic studies with advances in these fields enable the early detection of complications. Emerging technologies, including point-of-care testing and AI-powered analysis, also enhance accuracy and speed.

Therapeutic interventions, including neonatal intensive care, respiratory therapy (CPAP, surfactant therapy), phototherapy for jaundice, and targeted antimicrobial therapies keep evolving. Emerging therapies, such as stem cell therapy, neuroprotective therapy, and precision medicine, have the potential to treat previously untreatable diseases.

This Special Issue provides a comprehensive examination of maternal and neonatal health challenges with an emphasis on early diagnosis and innovative therapies. By fostering clinical advancements and research insights, it aims to enhance survival rates and long-term health outcomes for mothers and newborns worldwide.

We are pleased to invite authors to submit original studies, meta-analyses, and reviews investigating new advances in the field of diagnosis and treatment of maternal and fetal health issues and neonatal care.

Dr. Dimitrios Papageorgiou
Guest Editor

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Keywords

  • maternal–fetal health
  • neonatal health
  • prenatal care
  • prenatal diagnosis
  • fetal growth
  • diabetes mellitus
  • hypertension
  • pre-eclampsia
  • congenital infections
  • gene therapies

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Published Papers (1 paper)

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Review

18 pages, 785 KiB  
Review
Tubal Ectopic Pregnancy: From Diagnosis to Treatment
by Dimitrios Papageorgiou, Ioakeim Sapantzoglou, Ioannis Prokopakis and Eleftherios Zachariou
Biomedicines 2025, 13(6), 1465; https://doi.org/10.3390/biomedicines13061465 - 13 Jun 2025
Viewed by 105
Abstract
The most frequent form of ectopic pregnancy, known as tubal pregnancy, leads to a dangerous situation where the fertilized ovum implants inside a fallopian tube, which can result in tubal rupture and severe bleeding. The purpose of this narrative review is to evaluate [...] Read more.
The most frequent form of ectopic pregnancy, known as tubal pregnancy, leads to a dangerous situation where the fertilized ovum implants inside a fallopian tube, which can result in tubal rupture and severe bleeding. The purpose of this narrative review is to evaluate all existing data regarding epidemiology, risk factors, pathophysiology, clinical presentation, diagnosis, and management of tubal ectopic pregnancy in order to provide a comprehensive understanding of this common yet difficult clinical condition. Prior ectopic pregnancy, together with tubal pathology and assisted reproduction, represent the main risk factors for this condition. The diagnosis relies on serial β-hCG tests combined with transvaginal ultrasonography, but laparoscopy serves as the diagnostic tool for cases with uncertain results. The treatment plan depends on the fallopian tube integrity, along with the patient’s hemodynamic condition. Patients with unruptured pregnancies who are hemodynamically stable receive methotrexate treatment as the preferred option, but surgical intervention with salpingectomy or salpingostomy becomes necessary in case of tubal rupture or when medical treatment fails. The development of laparoscopic procedures has led to better results and improved possibilities for fertility preservation. The psychological effects on patients require both counseling and follow-up care. Early detection, along with personalized management, helps decrease maternal complications and optimize reproductive outcomes. Full article
(This article belongs to the Special Issue Maternal-Fetal and Neonatal Medicine)
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