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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer-Associated Thrombosis: From Biomarkers to Diagnostic and Therapeutic Strategies to Optimize Treatment

edited by

Roberta Pancani

, Gualtiero Palareti and Emilia Antonucci

submission deadline 30 Jun 2026 | Viewed by 241 | Submission Open

Keywords: cancer-associated thrombosis; venous thrombosis; biomarkers; pulmonary embolism; precision medicine; diagnostic optimization

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in 3D Bioprinting: From Materials to Functional Tissue Constructs

edited by

Tina Maver

submission deadline 30 Jun 2026 | 1 articles | Viewed by 221 | Submission Open

Keywords: 3D bioprinting; tissue engineering; biofabrication; regenerative medicine; bioprinted skin; organ-on-a-chip; biomaterials; vascularized constructs

(This special issue belongs to the Section Biomedical Engineering and Materials)

Urogenital Cancers: New Molecular and Translational Aspects on Carcinogenesis and Treatments (2nd Edition)

edited by

Silvia Di Agostino

Vittoria Rago

and

Anna Perri

submission deadline 30 Jun 2026 | Viewed by 203 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cell carcinoma; testicular cancer; ovarian cancer; endometrial cancer; carcinogenesis; biomarkers; early diagnosis; upper urinary tract tumors; diagnosis; treatment; environmental factors; diet

(This special issue belongs to the Section Cancer Biology and Oncology)

Antipsychotics: 70 Years—2nd Edition

edited by

Giovanni Lentini

and

Serge Mignani

submission deadline 30 Jun 2026 | Viewed by 194 | Submission Open

Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; complementary medicine; psychosis; schizophrenia; bipolar disorder; Alzheimer’ s disease

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Morpho-Molecular and Genetic Basis of Cardiomyopathies

edited by

Andrea Frustaci

submission deadline 30 Jun 2026 | Viewed by 151 | Submission Open

Keywords: dilated cardiomyopathy; hypertrophic cardiomyopathy; restrictive cardiomyopathy; inflammatory cardiomyopathy; myocardial storage diseases; genetic investigations

(This special issue belongs to the Section Molecular and Translational Medicine)

Breast Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatments

edited by Ioanna Akrida

submission deadline 30 Jun 2026 | 1 articles | Viewed by 134 | Submission Open

Keywords: breast cancer carcinogenesis; triple-negative breast cancer (TNBC); HER2; endocrine therapy; neoadjuvant chemotherapy (NACT); immunotherapy; tumor profiling molecular tests; liquid biopsy circulating tumor cells (CTCs); circulating tumor DNA (ctDNA)

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Kidney Diseases Research

edited by

Yi-Che Lee

submission deadline 30 Jun 2026 | Viewed by 99 | Submission Open

Keywords: kidney diseases; biomarkers; artificial intelligence; diagnostics; dialysis; immunomodulation; regenerative medicine

Advances in Parkinson’s Disease Research

edited by Valentino Racki

submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; neurodegeneration; biomarkers; deep brain stimulation; infusion therapies; gut– brain axis; neuroinflammation; personalized medicine; atypical parkinsonism

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

AI/Machine Learning-Driven Multi-Omics Research in Oncology

edited by Wenjun Mao,

Renjun Gu

and Yize Mao

submission deadline 30 Jun 2026 | Viewed by 62 | Submission Open

Keywords: artificial intelligence; machine learning; multi-omics; oncology; precision medicine; biomarker discovery; cancer genomics; deep learning

(This special issue belongs to the Section Cancer Biology and Oncology)

Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical, and Translational Neuropsychiatry—3rd Edition

edited by

Masaru Tanaka

and Simone Battaglia

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; psychiatric disorders; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Cerebrovascular Disease: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by Kay Sin Tan

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: cerebrovascular diseases; stroke; intracerebral haemorrhage; intracranial atherosclerosis; small vessel disease; vascular dementia; pathophysiological mechanisms

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genetic Research of Hearing Loss

edited by Ling Lu, Jun Yang,

Min-Xin Guan

and

Maoli Duan

submission deadline 30 Jun 2026 | Viewed by 60 | Submission Open

Keywords: genetic; sensorineural hearing loss; inner ear drug delivery; gene therapy; genetic screening; hearing aids; cochlear implantation

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

The Aging Metabolism: Diabetes, Obesity, and Lifespan Insights

edited by

Rafael Ramírez-Carracedo

and

Rafael Moreno-Gómez-Toledano

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: metabolic diseases; aging; obesity; diabetes; cell signaling

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Novel Insights into Depression Research: Neurobiology, Models, Biomarkers and Therapies

edited by

Adela Magdalena Ciobanu

submission deadline 30 Jun 2026 | Viewed by 54 | Submission Open

Keywords: depression; neurobiology; biomarkers; experimental models; antidepressant therapies; personalized medicine; treatment resistance; pharmacology; psychiatric disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Thyroid Disorders: Comprehensive Insight from Functional Abnormalities, Structural Lesions to Autoimmunity

edited by

Darko Katalinić

submission deadline 30 Jun 2026 | Viewed by 47 | Submission Open

Keywords: thyroid gland pathology; autoimmunity; immunopathogenesis; diagnostic biomarkers; therapeutic strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

Current Status and Future Directions of Molecular Genetics and Genetic Diseases

edited by

Darko Katalinić

submission deadline 30 Jun 2026 | Viewed by 46 | Submission Open

Keywords: molecular genetics; genetic diseases; genetic therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Next-Generation Approaches in Clinical Antiviral Therapy: From Bench to Bedside

edited by

Pouya Hassandarvish

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: clinical antiviral therapy; antiviral potential; novel drug discovery platforms; host-targeted antivirals; drug repurposing; combination therapies; resistance mechanisms; clinical trial; viral infections; viral diseases

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Update on Cancer Therapy

edited by

Jian Ruan

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: cancer; cancer immunotherapy; targeted therapy; ccancer vaccines; therapeutic agents; drug resistance mechanisms

(This special issue belongs to the Section Cancer Biology and Oncology)

Artificial Intelligence Applications in Neuroscience and Brain Diseases

edited by

Marios Krokidis

submission deadline 30 Jun 2026 | Viewed by 41 | Submission Open

Keywords: neuroscience; brain diseases; neurology and neurodegeneration; artificial intelligence; machine learning; bioinformatics; neuroimaging; neurotechnology; multimodal data integration; brain– computer interfaces; personalized medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Hereditary Diseases: Insights from Genetic Perspectives

edited by

Maud de Dieuleveult

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: genetic mutations; inheritance patterns; genomic medicine; monogenic disorders; genetic counseling

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathogenesis and Treatment of Amyotrophic Lateral Sclerosis (ALS)

edited by

Dongsheng Fan

submission deadline 30 Jun 2026 | Viewed by 37 | Submission Open

Keywords: amyotrophic lateral sclerosis (ALS); multi-target therapy; drug repurposing; translational research; biomarkers; induced pluripotent stem cells (iPSCs); clinical trial design; AI-based prediction models; precise treatment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Intraoperative Neurophysiology: New Perspectives and Clinical Applications

edited by Riccardo Budai and Giada Pauletto

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: IOM (intra operative monitoring); MEP (motor evoked potentials); SEP (somatosensory evoked potentials); BAEP (brainstem acoustic evoked potentials); VEP (visual evoked potentials); EMG (electromyography); EEG (electroencephalography); EcoG (electrocorticography); epilepsy; cerebral tumors

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pathogenesis, Diagnosis and Treatment of Infectious Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence

(This special issue belongs to the Section Molecular and Translational Medicine)

Multiple Sclerosis: From Early Diagnosis to Personalized Treatment Strategies

edited by Alberto Calvi

submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open

Keywords: multiple sclerosis; susceptibility; deformation-based techniques; PRL; GFAP; machine learning

(This special issue belongs to the Section Immunology and Immunotherapy)

Nano-Mediated Drug Delivery

edited by

Zhengxing Li

submission deadline 30 Jun 2026 | Viewed by 29 | Submission Open

Keywords: engineered nano-carriers; nanomedicine; micro/nanorobotics; targeted drug delivery; intelligent controllable systems; biohybrid systems; RNA therapeutics; translational nanotechnology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Precision Oncology in Solid Tumors: Emerging Biomarkers and Therapeutic Targets

edited by Giuseppe Nicolò Fanelli

submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open

Keywords: precision oncology; predictive biomarkers; target therapy; molecular pathology; liquid biopsy; tumor microenvironment; immunotherapy; multi-omics integration; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (3rd Edition)

edited by Sung Il Im

submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open

Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Lipid Nanoparticles for Cancer Immunotherapy

edited by Qiyan Wang

submission deadline 30 Jun 2026 | Viewed by 27 | Submission Open

Keywords: mRNA; LNP; cancer vaccine; immune therapy; target delivery

(This special issue belongs to the Section Immunology and Immunotherapy)

Genomics and Epitranscriptomics Regulation in Cancer

edited by Ilias Georgakopoulos-Soares and

Candace S. Y. Chan

submission deadline 30 Jun 2026 | Viewed by 22 | Submission Open

Keywords: cancer genomics; epitranscriptomics; RNA modifications; non-coding RNAs; gene expression regulation; RNA splicing

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research in Hematological Malignancies

edited by

Te-Fu Weng

submission deadline 30 Jun 2026 | Viewed by 22 | Submission Open

Keywords: hematological malignancies; leukemia; lymphoma; myeloma

(This special issue belongs to the Section Cancer Biology and Oncology)

Viral Hepatitis: From Pathophysiology to Therapeutic Approaches

edited by

Manish C. Choudhary

submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open

Keywords: viral hepatitis; hepatotropic viruses; viral persistence; immunomodulatory; antiviral resistance

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advances in the Pathogenesis and Therapeutics of Pulmonary Disease

edited by Sara Manti and

Paolo Ruggeri

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: pulmonary diseases; pathogenesis; therapeutic targets; drug discovery; respiratory inflammation; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Immunology in Recurrent Pregnancy Loss, Preeclampsia and Infertility

edited by

Jenny Valentina Garmendia

submission deadline 30 Jun 2026 | Viewed by 18 | Submission Open

Keywords: immunology of pregnancy; recurrent pregnancy loss; infertility; preeclampsia; autoimmunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Targeted Nanomedicine: From Design to Application

edited by

Ming Ma

submission deadline 30 Jun 2026 | Viewed by 17 | Submission Open

Keywords: targeted nanomedicine; nanocarriers; nanosystems; drug delivery

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Neonatal Disease: From Pathophysiology to Current and Emerging Therapeutic Approaches (3rd Edition)

edited by

Fumihiko Namba

submission deadline 30 Jun 2026 | Viewed by 6 | Submission Open

Keywords: fetal therapy; neonatal diseases; pathophysiology; innovative therapeutic approaches

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiac Arrhythmias: Technological Frontiers, Therapeutic Approaches and Future Directions

edited by

Panteleimon Pantelidis

Polychronis E. Dilaveris

, Raffaele De Lucia and

Evangelos Oikonomou

submission deadline 30 Jun 2026 | Viewed by 5 | Submission Open

Keywords: cardiac arrhythmias; electrophysiology; implantable devices; artificial intelligence; translational medicine; arrhythmogenesis; e-cardiology; biomarkers; telemonitoring

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Melanoma Metastasis

edited by

Viktória Koroknai

submission deadline 30 Jun 2026 | Viewed by 4 | Submission Open

Keywords: melanoma; metastasis; tumor– host interactions; pre-metastatic niche; tumor microenvironment; organ-specific metastasis; molecular mechanisms; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Bowel Cancer: From Early Diagnosis to Personalized Treatment Strategies

edited by Maximos Frountzas

submission deadline 30 Jun 2026 | Viewed by 2 | Submission Open

Keywords: colorectal cancer; precision oncology; liquid biopsy; circulating tumor DNA (ctDNA); molecular biomarkers; radiomics and radiogenomics; artificial intelligence in oncology; tumor microenvironment; personalized therapy; early cancer detection

(This special issue belongs to the Section Cancer Biology and Oncology)

Technologies and Applications of Genome Editing

edited by Fu-Lei Tang

submission deadline 30 Jun 2026 | Submission Open

Keywords: genome manipulation; CRISPR/Cas systems; preclinical animal models; translational research; editing efficiency; base editing and prime editing; genetically engineered mouse models (GEMMs); virus-like particles (VLPs)

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Advances of Biomedical Engineering and Materials

edited by Mei-Jung Chen,

Yaw Sing Tan

and

Chuan Li

submission deadline 30 Jun 2026 | Submission Open

Keywords: tissue engineering; artificial intelligent biocompatible materials; cell therapy; drug delivery system

(This special issue belongs to the Section Biomedical Engineering and Materials)

Emerging Molecular and Translational Insights into Obstructive Sleep Apnea and Its Cardiovascular Comorbidities

edited by Hui-Ting Wang and

Yunglung Chen

submission deadline 30 Jun 2026 | Submission Open

Keywords: obstructive sleep apnea (OSA); atrial fibrillation (AF); molecular mechanisms; epigenetics; biomarkers; oxidative stress; inflammation; endothelial dysfunction; translational research; precision medicine; artificial intelligence; cardiovascular comorbidities

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in the Diagnosis and Treatment of Urothelial Cancers

edited by Aleksander Ślusarczyk and

Łukasz Zapała

submission deadline 30 Jun 2026 | Submission Open

Keywords: bladder cancer; urethral cancer; upper tract urothelial carcinoma

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Extracellular Vesicles in Therapeutics

edited by

Mangesh D. Hade

and

Akil Akhtar

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1870 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; regenerative medicine; immunotherapy; nanocarriers; biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

State-of-the-Art Molecular and Translational Medicine in Japan

edited by

Takemichi Fukasawa

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1525 | Submission Open

Keywords: molecular and translational research; targeting inflammatory cytokines; targeted drugs; skin diseases; basic mechanisms; novel therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Strategies for Oncogene-Addicted Lung Cancers: Not Rare Anymore

edited by

Carminia Maria Della Corte

submission deadline 31 Jul 2026 | Viewed by 224 | Submission Open

Keywords: target therapy; EMT; biomarkers; cancer mutations; preclinical models

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomedical Applications of Microfluidics

edited by

Surjendu Maity

submission deadline 31 Jul 2026 | Viewed by 121 | Submission Open

Keywords: microfluidics; organ-on-a-chip; lab-on-a-chip; disease modeling; regenerative medicine; cancer immunotherapy; biosensors; mathematical modeling; AI/ML; realtime sensing

(This special issue belongs to the Section Biomedical Engineering and Materials)

Skeletal Muscle Ageing: From Molecular Mechanism to Treatment

edited by Can Cui and

Manuela Bozzi

submission deadline 31 Jul 2026 | Viewed by 69 | Submission Open

Keywords: skeletal muscle aging; sarcopenia; muscle regeneration; neuromuscular degeneration; molecular mechanisms of aging; mitochondrial dysfunction; inflammation and aging; therapeutic interventions; exercise and muscle health; musculoskeletal disorders in aging

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cardiac Dysfunction: From Early Detection to Innovative Therapies

edited by

Carla Contaldi

submission deadline 31 Jul 2026 | Viewed by 51 | Submission Open

Keywords: cardiac dysfunction; heart failure; early detection; advanced heart failure; advanced cardiac imaging; biomarkers; innovative therapies; risk stratification; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancing Precision Radiation Oncology in Head and Neck Cancers

edited by

Wing-Keen Yap

submission deadline 31 Jul 2026 | Viewed by 33 | Submission Open

Keywords: precision radiation oncology; head and neck cancers; oncogenetics; genomic biomarkers; radiosensitivity; adaptive radiotherapy; artificial intelligence; immunotherapy integration; proton therapy; deescalation strategies

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Research of Chronic Kidney Disease

edited by Jingyuan Xie

submission deadline 31 Jul 2026 | Viewed by 25 | Submission Open

Keywords: chronic kidney disease; molecular mechanisms; biomarker discovery; inflammation; fibrosis; genetic kidney disease; glomerulonephritis; diabetic nephrology

(This special issue belongs to the Section Molecular and Translational Medicine)

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