Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microbial Responses, Pollutant Toxicity Mechanisms, and Human Health Implications
edited by , Zhongquan Jiang and
submission deadline 10 Jul 2026 | 3 articles | Viewed by 3206 | Submission Open
Keywords: heavy metal and emerging pollutants; microbiology and plant physiology; aquatic biology; environmental chemistry; anthropogenic disturbances; machine learning; pangenome analysis; computational toxicology; human health
Ultrastructure and Function in In Vitro Cancer Models: From Morphology to Mechanism submission deadline 15 Jul 2026 | 1 articles | Viewed by 2188 | Submission Open
Keywords: cancer; organoids; spheroids; transmission electron microscopy; scanning electron microscopy; focused ion beam (FIB)
(This special issue belongs to the Section Cancer Biology)
Molecular Mechanisms of Bone Metastasis in Cancer
edited by Ana Carolina Dos Santos Monteiro
submission deadline 15 Jul 2026 | 1 articles | Viewed by 2170 | Submission Open
Keywords: bone metastasis; osteoimmunology; tumor–immunity interactions; myeloid-derived suppressor cells; RANKL/OPG signaling; TGF-β; Wnt; immune evasion; extracellular vesicles; metastatic niche; cancer cell dormancy; preclinical models
(This special issue belongs to the Section Cancer Biology)
Plant Perception, Behavior, and Environmental Response Mechanisms
edited by and Bianca Bonato
submission deadline 15 Jul 2026 | Viewed by 336 | Submission Open
Keywords: plant perception; plant movement; social cognition; communication; plant behavior; climbing plants; interactions; plant–plant interactions; environment; plant–environment interactions
(This special issue belongs to the Section Plant Science)
Methods in Bioinformatics and Computational Biology
edited by
submission deadline 25 Jul 2026 | 2 articles | Viewed by 2943 | Submission Open
Keywords: bioinformatics; computational biology; machine learning in biomedicine; artificial intelligence; single-cell and spatial transcriptomics analysis; biological network analysis; high-throughput data analysis
Tissue and Organ Regeneration in Fish: Evolutionary Mechanisms
edited by Yujun Liang
submission deadline 30 Jul 2026 | 1 articles | Viewed by 7624 | Submission Open
Keywords: organ and tissue regeneration; regeneration mechanisms; progenitor cells; dedifferentiation; fishes; evolutionary adaptation; genetic regulation; signaling pathways; comparative genomics
(This special issue belongs to the Section Evolutionary Biology)
Plant Natural Products: Mechanisms of Action for Promoting Health submission deadline 31 Jul 2026 | 16 articles | Viewed by 52017 | Submission Open
Keywords: phytochemicals; bioactivity; therapeutics; mechanisms; health promotion; metabolism; enzyme activity; bioactive compounds; pharmacognosy; plant extracts; polyphenols; ethnopharmacology; essential oils; aromatic plants; antioxidants; natural products
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Animal Models of Metabolic Diseases submission deadline 31 Jul 2026 | 8 articles | Viewed by 20789 | Submission Open
Keywords: experimental models; metabolic syndrome; insulin resistance; type 2 diabetes mellitus; obesity; dyslipidemia; hypertension; metabolic programming; DOHaD
(This special issue belongs to the Section Physiology)
Dendrochronology in Arid and Semiarid Regions
edited by
submission deadline 31 Jul 2026 | 6 articles | Viewed by 18388 | Submission Open
Keywords: tree rings; growth–climate response; dendrochronology; dendroecology; dryland regions
(This special issue belongs to the Section Ecology)
Reproductive Physiology and Pathology in Livestock
edited by Claudio Gustavo Ustavo Barbeito and
submission deadline 31 Jul 2026 | 7 articles | Viewed by 13340 | Submission Open
Keywords: livestock; animal reproduction; reproductive biology; physiology and pathology of reproduction; experimental models; non-conventional species; biotechnology; immunology
(This special issue belongs to the Section Developmental and Reproductive Biology)
Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development submission deadline 31 Jul 2026 | 6 articles | Viewed by 13177 | Submission Open
Keywords: HLA; vaccine; antigen; antibody; cancer; binding affinity; biophysical modeling; lymphocytes
Unraveling the Tumor-Immune Microenvironment Using Transcriptomics submission deadline 31 Jul 2026 | 3 articles | Viewed by 11975 | Submission Open
Keywords: tumor-immune microenvironment; immune cells; tumor cells; stromal cells; signaling molecules; extracellular matrix (ECM); vascular network
(This special issue belongs to the Section Cancer Biology)
Ecological Regulation of Forest and Grassland Pests
edited by and Liangjian Qu
submission deadline 31 Jul 2026 | 7 articles | Viewed by 11799 | Submission Open
Keywords: forest and grassland pests; ecological regulation; sustainable IPM; biological control; forest management
(This special issue belongs to the Section Ecology)
Unraveling the Molecular Mechanisms of Development and Stress Tolerance in Vegetables
edited by , and
submission deadline 31 Jul 2026 | 4 articles | Viewed by 11650 | Submission Open
Keywords: vegetable development; molecular mechanisms; stress tolerance; genetic regulation; epigenetic regulation; biochemical regulation; sustainable agriculture; environmental stress; growth adaptation; crop yield; gene editing; cellular engineering
(This special issue belongs to the Section Plant Science)
Phytoplasmas: Molecular Characterization and Host–Pathogen Interactions (2nd Edition)
edited by
submission deadline 31 Jul 2026 | 5 articles | Viewed by 11582 | Submission Open
Keywords: molecular diagnosis and epidemiology; host-phytoplasma interactions; genetic diversity; taxonomy and classification; ecology and evolution; insect vectors; disease management; phytoplasma genomics and other omics studies
(This special issue belongs to the Section Microbiology)
The Biodiversity and Ecosystem Dynamics of Deep-Sea Hydrothermal Vents
edited by and Yadong Zhou
submission deadline 31 Jul 2026 | 4 articles | Viewed by 10172 | Submission Open
Keywords: deep-sea hydrothermal vents; biodiversity; microbiome; biological resources; marine biology
(This special issue belongs to the Section Marine and Freshwater Biology)
The Relationship Between Water Quality and Aquatic Organisms (2nd Edition)
edited by Dong Zhang, , , and Mengmeng Yi
submission deadline 31 Jul 2026 | 4 articles | Viewed by 9196 | Submission Open
Keywords: aquatic animals; water quality; phytoplankton; zooplankton; microorganisms; physiology
Milk Oligosaccharides: Biological Functions and Application Prospects
edited by
submission deadline 31 Jul 2026 | 3 articles | Viewed by 9008 | Submission Open
Keywords: milk oligosaccharides; colostrum; HMO; gut microbiota; immune modulator; prebiotics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Cellular and Molecular Mechanisms in Sensory–Metabolic Integration: From Signaling Pathways to Systemic Regulation
edited by , Giovanni Giurdanella, Mohamed Amin Zaoual and
submission deadline 31 Jul 2026 | 4 articles | Viewed by 8409 | Submission Open
Keywords: multisensory disorders; metabolic dysfunction; systemic health; sensory impairments; metabolic syndrome; neurometabolic pathways; vision impairment; hearing loss; vestibular disorders; olfactory dysfunction; gustatory dysfunction; somatosensory impairment; energy homeostasis; integrative medicine
(This special issue belongs to the Section Biochemistry and Molecular Biology)
The Future of Marine Megafauna submission deadline 31 Jul 2026 | 4 articles | Viewed by 7310 | Submission Open
Keywords: marine biodiversity; marine megafauna; anthropogenic impacts; conservation biology; marine ecosystems; behavioural ecology; marine protected areas (MPAs); ecological resilience; evolutionary biology; species recovery strategies
(This special issue belongs to the Section Zoology)
Osteoblast Differentiation in Health and Disease submission deadline 31 Jul 2026 | 4 articles | Viewed by 6992 | Submission Open
Keywords: osteogenesis; mesenchymal stem cells; osteoblast; osteoblast differentiation; bone diseases; transcription factors; epigenetics; extracellular vesicles; inflammatory mediators; bioactive natural compounds
(This special issue belongs to the Section Biochemistry and Molecular Biology)
2nd Edition: Conservation and Evolution of Wildlife in the Context of Climate Change and Human Population Growth
edited by
submission deadline 31 Jul 2026 | 4 articles | Viewed by 5647 | Submission Open
Keywords: changes; local temperature; adaptation; evolution; animals; plants
(This special issue belongs to the Section Behavioural Biology)
Environmental and Nutritional Stress: Metabolic Consequences and Regulatory Strategies in Animals
edited by
submission deadline 31 Jul 2026 | 6 articles | Viewed by 4857 | Submission Open
Keywords: stress physiology; metabolic dysfunction; environmental stress; nutritional stress; gut microbiota; bioactive compounds
(This special issue belongs to the Section Physiology)
Advances in Plant Genomics and Genome Editing
edited by Xuean Cui
submission deadline 31 Jul 2026 | 7 articles | Viewed by 4602 | Submission Open
Keywords: plant genomes; plant genomics; genome sequencing; plant genome engineering; CRISPR/Cas; gene knock-out; gene knock-in; base editor; prime editor; genome editing tools; multiplex genome editing; gene expression regulation; plant trait improvement
(This special issue belongs to the Section Genetics and Genomics)
Tickborne Diseases and Their Vectors
edited by Moses Sibusiso Mtshali
submission deadline 31 Jul 2026 | 2 articles | Viewed by 4366 | Submission Open
Keywords: ticks; tickborne pathogens; epidemiology of tickborne diseases; zoonotic diseases; molecular diagnosis; genetic diversity; immunology; vector control and mapping
(This special issue belongs to the Section Infection Biology)
Advances in Foodborne Pathogens
edited by Qiming Chen
submission deadline 31 Jul 2026 | 3 articles | Viewed by 4268 | Submission Open
Keywords: foodborne pathogens; contamination mechanisms; infection mechanisms; detection assays; risk assessment; antibacterial agents or materials
(This special issue belongs to the Section Microbiology)
Research on Morphology and Sensorimotor Systems of Insect Antennae
edited by Lifeng Meng
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3195 | Submission Open
Keywords: antennae structure; sensilla; olfaction; olfactory receptors; sensory integration; antenna lobe; pheromones; predator avoidance; foraging behavior
(This special issue belongs to the Section Zoology)
Advances in Redox Metabolism and Cellular Homeostasis submission deadline 31 Jul 2026 | 1 articles | Viewed by 2942 | Submission Open
Keywords: oxidative stress; peroxiredoxins; hydrogen peroxide; redox regulation; thiol modification; reactive oxygen species; iron sulfur clusters; redox signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Regulation of Gene Expression in Immune Cell Development and Function
edited by Bon Quy Trinh
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1766 | Submission Open
Keywords: noncoding RNA; enhancer; silencer; transposable element; epigenetics; chromatin structure and architecture; innate immunology; adaptive immunology; development; functions
(This special issue belongs to the Section Immunology)
Mode of Action of Allelopathic Compounds
edited by and Paweł Staszek
submission deadline 31 Jul 2026 | 1 articles | Viewed by 855 | Submission Open
Keywords: metabolomics; phytotoxic potential; mode of action; sustainable bioherbicides; root exudates; plant–plant interaction; plant–microbe interaction; metabolic malformations; biosynthesis of allelochemicals
(This special issue belongs to the Section Plant Science)
Reprogramming Life: Synthetic Biology Approaches for Next-Gen Strain Engineering
edited by Thanaporn Laothanachareon, and
submission deadline 31 Jul 2026 | Viewed by 817 | Submission Open
Keywords: synthetic biology; strain engineering; metabolic pathway redesign; CRISPR/Cas genome editing; microbial cell factories; multi-omics integration; AI-driven metabolic design; sustainable bioproduction
(This special issue belongs to the Section Biotechnology)
Epilepsy: The Mechanisms of Seizure, Termination, and Biomarker Development
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 730 | Submission Open
Keywords: epilepsy; epileptogenesis; seizure mechanisms; seizure dynamics; termination; biomarkers; neural excitability; neuroscience
(This special issue belongs to the Section Neuroscience)
Exploring the Role of Serotonin in Psychiatric Disorders
edited by
submission deadline 31 Jul 2026 | Viewed by 532 | Submission Open
Keywords: diet; drug treatments; enzymes; epigenetic; post translational modification; serotonin metabolism; serotonin receptors; serotonin transporters
(This special issue belongs to the Section Neuroscience)
CRISPR-Engineered Mouse Models for Unraveling Rare Diseases submission deadline 31 Jul 2026 | Viewed by 385 | Submission Open
Keywords: mouse models; CRISPR/Cas9; rare disease modeling; phenotyping; translational research; svatar mice
(This special issue belongs to the Section Medical Biology)
Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services—3rd Edition submission deadline 31 Jul 2026 | Viewed by 353 | Submission Open
Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation
(This special issue belongs to the Section Marine and Freshwater Biology)
Animal Cognition and Decision Strategies: From Behaviour to Computation
edited by and
submission deadline 31 Jul 2026 | Viewed by 292 | Submission Open
Keywords: animal models; bio-inspired computation; brain–behaviour mapping; cognitive mechanisms; cognitive neuroscience; cognitive strategies; comparative cognition; computational modelling; decision-making; learning and adaptation; naturalistic behaviour; neural computation; neuroethology
(This special issue belongs to the Section Neuroscience)
Applications of Gene Expression Profiling in Human Disease
edited by
submission deadline 31 Jul 2026 | Viewed by 258 | Submission Open
Keywords: gene expression profile; biomarkers; cancer; complex disease
(This special issue belongs to the Section Genetics and Genomics)
Ferroptosis: Mechanisms and Human Disease
edited by Chan-Yen Kuo
submission deadline 15 Aug 2026 | 5 articles | Viewed by 15757 | Submission Open
Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment
(This special issue belongs to the Section Cell Biology)
Gut Microbiota in Aquatic Animals Nutrition, Immunity, and Host–Microbe Interactions
edited by Qunlan Zhou
submission deadline 15 Aug 2026 | 3 articles | Viewed by 7292 | Submission Open
Keywords: gut microbiota; aquatic animal health; host–microbe interactions; functional probiotics; immunomodulation; nutrient metabolism; multi-omics integration; microbial ecology; environmental adaptation
(This special issue belongs to the Section Microbiology)
Changing Coral Reef Biodiversity and Function in the Anthropocene
edited by
submission deadline 15 Aug 2026 | 1 articles | Viewed by 1860 | Submission Open
Keywords: anthropogenic stressors; coral reefs; climate change; biodiversity loss; marine conservation; ecological adaptation; ecosystem function; resilience
(This special issue belongs to the Section Marine and Freshwater Biology)
Role of CARD9 in Health and Diseases
edited by Zuberwasim Sayyad and Nikhil Sharma
submission deadline 15 Aug 2026 | Viewed by 730 | Submission Open
Keywords: CARD9; innate immunity; pattern recognition receptors; autophagy; apoptosis; inflammasome; reactive oxygen species; post-translational modifications; gut microbiota; inflammation and cancer
Recent Advances in Angiogenesis and Vascular Development submission deadline 15 Aug 2026 | Viewed by 221 | Submission Open
Keywords: vasculogenesis; angiogenesis; vascular differentiation markers; endothelial-to-mesenchymal transition (EndMT); mechanotransduction; endothelial function; endothelial damage
(This special issue belongs to the Section Cell Biology)
The Role of Autophagy and Macrophages in Modulating Immune Responses in Atherosclerosis
edited by and Aatira Vijay
submission deadline 25 Aug 2026 | Viewed by 750 | Submission Open
Keywords: atherosclerosis; macrophages; autophagy; immune regulation; chronic inflammation; plaque stability; lipid metabolism; efferocytosis; immunometabolism
Population Genetics and Conservation of Amphibians and Reptiles
edited by
submission deadline 25 Aug 2026 | Viewed by 355 | Submission Open
Keywords: conservation genetics; local adaptation; genetic diversity; amphibian; reptile; environmental change
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Animal Models of Arthritis
edited by Nevena Arsenović-Ranin and Biljana Bufan
submission deadline 30 Aug 2026 | 4 articles | Viewed by 15544 | Submission Open
Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine
(This special issue belongs to the Section Medical Biology)
Young Researchers in Neuroscience
edited by
submission deadline 31 Aug 2026 | 7 articles | Viewed by 68441 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Bone Cell Biology
edited by Yohei Abe and
submission deadline 31 Aug 2026 | 8 articles | Viewed by 28870 | Submission Open
Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling
(This special issue belongs to the Section Cell Biology)
Biology, Ecology and Management of Harmful Algae
edited by Paul V. Zimba and
submission deadline 31 Aug 2026 | 9 articles | Viewed by 16886 | Submission Open
Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources
Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease submission deadline 31 Aug 2026 | 3 articles | Viewed by 13820 | Submission Open
Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle
Insecticide Resistance: Molecular Mechanisms and Ecological Implications
edited by Kaikai Mao
submission deadline 31 Aug 2026 | 1 articles | Viewed by 9412 | Submission Open
Keywords: insecticide resistance; molecular mechanism; regulatory network; ecological impact; non-target impact; resistance genes; pest resistance management
(This special issue belongs to the Section Ecology)
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