Extracellular Chaperones and Related miRNA as Diagnostic Tools of Chronic Diseases

Dear Colleagues,

Chaperones and related miRNAs are actively involved in crucial biological processes such as cell differentiation, tissue homeostasis, and organ remodeling throughout all the life span of an individual. An impairment of their function, if not counterbalanced by rescue mechanisms, can lead to the rise and/or perpetuation of human diseases by several—mostly unknown—etiopathophysiological mechanisms.

The aim of this Special Issue is to collect breakthrough papers focusing on data supporting that extracellular chaperones and their related miRNA (including either those in their soluble form or those hosted in extracellular vesicles) may represent innovative diagnostics tool in many chronic human pathologies. We will particularly consider papers that—other than presenting solid data on the aforementioned aim—also discuss original data about mechanistic roles of these molecules inside and outside cells.

Taken all together, the accepted papers will form a Special Issue that would represent a landmark in the scientific literature about this important issue that—in our opinion—is of interest for many scientists working in the fields of biomedicine, neuroscience, and advanced diagnostics.

Prof. Dr. Francesco Cappello
Dr. Magdalena Gorska-Ponikowska
Prof. Dr. Claudia Marino
Dr. Francesca Rappa
Guest Editors

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