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Applied Sciences
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Biomechanical Analysis in Bioengineering: New Trends and Perspectives, 2nd Edition
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Biomechanical Analysis in Bioengineering: New Trends and Perspectives, 2nd Edition

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 857

Editors

Dr. Cristina Curreli

E-Mail Website
Guest Editor
Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, 0039 051 Bologna, Italy
Interests: biotribology; biomechanics; numerical modelling; in silico medicine
Special Issues, Collections and Topics in MDPI journals
Dr. Pierpaolo Palumbo

E-Mail Website
Guest Editor
Department of Electrical, Electronic, and Information Engineering 'Guglielmo Marconi', University of Bologna, 240136 Bologna, BO, Italy
Interests: bioengineering; data analysis; preventive medicine; ageing; falls; prostheses; personalised medicine; predictive models
Special Issues, Collections and Topics in MDPI journals
Dr. Antonino Amedeo La Mattina

E-Mail Website
Guest Editor
Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, 0039 051 Bologna, Italy
Interests: patient-specific modelling; HPC; computational biomechanics; data analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of biomechanical analyses will continue to advance our understanding of different mechanical aspects of biological systems. Advanced experimental and computational biomechanics techniques are expected to play a crucial role in personalised medicine, prevention, monitoring, diagnosis, treatment, rehabilitation, and assistive devices.

This Special Issue aims to explore the latest trends in and perspectives on biomechanical analysis in diverse areas within the field of biomechanics. We invite submissions of original research articles, reviews, perspectives, and methodological studies that address emerging biomechanical technologies.

Topics of interest include, but are not limited to, the following:

  • Computational biomechanics;
  • Experimental biomechanics;
  • Advanced imaging techniques for biomechanical analyses;
  • Biomaterials and implants;
  • Cardiovascular and respiratory biomechanics;
  • Orthopaedic biomechanics;
  • Sports biomechanics;
  • Human movement and ergonomics;
  • Multidisciplinary approaches for biomechanics;
  • Physics-based and data-driven biomechanical models;
  • High-performance computing for biomechanical analyses.

Dr. Cristina Curreli
Dr. Pierpaolo Palumbo
Dr. Antonino Amedeo La Mattina
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioengineering
  • data analysis
  • computational biomechanics
  • experimental biomechanics
  • personalised medicine

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Published Papers (2 papers)

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Research

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15 pages, 4896 KB  
Article
Beyond Jump Height: Load-Dependent Effects of Lightweight Wearable Resistance on Countermovement and Drop Jump Biomechanics
by Hamish Kyne and John B. Cronin
Appl. Sci. 2026, 16(17), 8433; https://doi.org/10.3390/app16178433 (registering DOI) - 24 Aug 2026
Abstract
Of interest were the acute effects of lightweight lower-limb wearable resistance (WR) on the kinematics and kinetics of the countermovement jump (CMJ) and drop jump (DJ). Twenty male athletes (age: 18.05 ± 0.6 years; body mass: 76.4 ± 7.6 kg; height: 182.4 ± [...] Read more.
Of interest were the acute effects of lightweight lower-limb wearable resistance (WR) on the kinematics and kinetics of the countermovement jump (CMJ) and drop jump (DJ). Twenty male athletes (age: 18.05 ± 0.6 years; body mass: 76.4 ± 7.6 kg; height: 182.4 ± 5 cm) performed the CMJ and DJ under four loading conditions: 0%, 2%, 4%, and 6% body mass (BM). Variables of interest included jump height (JH), countermovement depth (CMD), total SSC duration (TCT/GCT), eccentric and concentric phase durations, relative concentric impulse (rCI), relative concentric mean force (rCMF), relative concentric mean power (rCMP), and concentric force index (CFI). Two-way repeated-measures ANOVAs were used to assess jump × load interactions, with Bonferroni-adjusted pairwise comparisons and planned contrasts used to examine within-jump and between-jump load responses, respectively. Significant jump × load interactions were observed for all variables analysed. In the CMJ, JH significantly decreased across all loaded conditions, including an 8.3% reduction with 2% BM. In contrast, DJ JH was preserved at 2% BM but significantly decreased at 4% and 6% BM. However, 2% BM was sufficient to increase DJ GCT and ConT, and reduce rCMF, CFI, and rCMP (p < 0.05). The change in JH differed between jumps at 2% BM only, whereas changes in CMD, rCMF, CFI, and rCMP differed between jumps across all WR loads. It appears that lightweight WR produces distinct jump-specific responses. Greater initial changes in CMJ JH and CMD suggest that WR altered countermovement strategy before substantially impairing concentric force production, whereas in the DJ, WR altered fast SSC force–time variables before reducing JH. When utilising WR to improve JH performance, practitioners should therefore avoid interpreting JH in isolation and monitor temporal variables (GCT/TCT/ConT/EccT), CMD, rCMF, rCMP and CFI. Full article
(This article belongs to the Special Issue Biomechanical Analysis in Bioengineering: New Trends and Perspectives, 2nd Edition)
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Review

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23 pages, 7393 KB  
Review
Reducing Stress Shielding in Cementless Total Hip Arthroplasty: A Translational Review of the Gradient-Modulus Ti-Nb-Sn Femoral Stem
by Yu Mori, Hidetatsu Tanaka, Kazuyoshi Baba, Ryuichi Kanabuchi, Naoko Mori and Toshimi Aizawa
Appl. Sci. 2026, 16(11), 5630; https://doi.org/10.3390/app16115630 - 4 Jun 2026
Viewed by 513
Abstract
Stress shielding (SS) after cementless total hip arthroplasty arises from the stiffness mismatch between conventional Ti-6Al-4V femoral stems (110 GPa) and cortical bone (10–30 GPa). The β-type Ti-33.6Nb-4Sn (TNS) alloy femoral stem addresses this limitation through a continuous Young’s modulus gradient (~70 GPa [...] Read more.
Stress shielding (SS) after cementless total hip arthroplasty arises from the stiffness mismatch between conventional Ti-6Al-4V femoral stems (110 GPa) and cortical bone (10–30 GPa). The β-type Ti-33.6Nb-4Sn (TNS) alloy femoral stem addresses this limitation through a continuous Young’s modulus gradient (~70 GPa proximally to ~40 GPa distally) achieved by localized heat treatment of a single homogeneous alloy. This review synthesizes a translational research program encompassing material characterization, finite element modeling (FEM), preclinical animal studies, and prospective clinical follow-up of up to seven years. FEM demonstrated favorable proximal micromotion well below the osseointegration threshold, with physiological proximal stress concentration concordant with clinical outcomes. At seven years, SS grade distribution was significantly lower in the TNS group than in Ti-6Al-4V controls, with SS frequency reduced in Gruen Zones 2, 3, and 6, and no stem-related failures; however, third-degree SS was still observed in 11 of 34 evaluable cases (32%), indicating that modulus-gradient optimization alone is insufficient to fully prevent SS. TNS alloy is currently the only β-type titanium alloy clinically applied in joint prostheses. Remaining challenges include stem geometry optimization, additive manufacturing-based porous structures, and dual-energy X-ray absorptiometry-based bone density quantification. Future directions encompass long-term follow-up, cyclic fatigue FEM simulations, and expansion to fracture fixation devices and dental implants. Full article
(This article belongs to the Special Issue Biomechanical Analysis in Bioengineering: New Trends and Perspectives, 2nd Edition)
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