After Antibiotics: Dysbiosis and Drug Resistance in Gut Microbiota

Dear Colleagues,

The growing incidence of antibiotic resistance and an increasing awareness of antibiotic-associated dysbiosis underscore the critical necessity of reevaluating our strategies regarding antimicrobial application and intestinal microbiota well-being. Antibiotic exposure can significantly disrupt the composition and function of the intestinal microbial ecosystem, resulting in enduring metabolic, immunological, and physiological effects. Simultaneously, the rapidly occurring emergence of multidrug-resistant microorganisms continues to pose a significant threat to global public health, highlighting the urgent need for novel therapeutic and preventive approaches.

This Special Issue, “After Antibiotics: Dysbiosis and Drug Resistance in Gut Microbiota”, will provide a comprehensive platform for advanced research examining the mechanisms, effects, and interventions associated with microbiota disturbances and antibiotic resistance. We welcome original research articles, reviews, and perspectives focusing on microbiome restoration strategies, novel antimicrobial alternatives, resistance genetics, host–microbe interactions, and translational approaches to mitigating the adverse effects of antibiotic use.

We look forward to receiving your valuable contributions and working together to advance the scientific understanding of post-antibiotic microbiota resilience and resistance management.

Prof. Dr. Sercan Karav
Guest Editor

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