Adaptive Evolution of Bacterial Pathogens in Response to Antibiotic Therapy
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3155
Special Issue Editor
Special Issue Information
Dear Colleagues,
Bacterial pathogens have developed numerous methods to circumvent antibiotic therapy and cause long-term infections. In many instances, adaptations that occur during infection are pleiotropic and affect physiology, host-immune interactions, and pathogenesis.
Next-generation genome sequencing provides a technical platform to map and characterize adaptive mutations that are selected for during infection. The current Special Issue focuses on new mechanisms that alter treatment efficacy, immune responses, and/or bacterial virulence for the common nosocomial ‘ESKAPE’ pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp), as well as for less-typical pathogens that may infrequently cause long-term human disease.
Dr. David Robert Cameron
Guest Editor
Manuscript Submission Information
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Keywords
- Comparative genomics
- functional genomics
- microbial evolution
- antibiotic resistance
- pathogenesis
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