Synopsis on Antimicrobials Challenges—from Dentistry to Environmental Visions

Dear Colleagues,

Oral diseases including dental caries and periodontitis are associated with microbiome shifts, and microbial-based therapies are known to be implicated in the control of these diseases. The clinical situations that require antimicrobial therapy on an empirical basis are limited and include oral infection accompanied by elevated body temperature and evidence of systemic spread. Despite the limited indications for antimicrobial use in the treatment of oral infections in published clinical guidelines, antimicrobial drugs are continuously being prescribed by dentists world-wide. Antimicrobial resistance poses a substantial threat to global public health. Host-related environmental factors play a vital role in the prevalence and treatment outcome of oral diseases. Considering this viewpoint, dental practitioners and researchers are trying to explore advanced strategies to improve oral health and host environmental factors in oral diseases, so to ameliorate treatment outcomes. Therefore, in the milieu of the well-documented antimicrobial resistance as a challenge faced by researchers and practitioners, we need to focus on how we can prevent the emergence of new antimicrobial resistance problems and control the ones already existing. We also need to focus on multidisciplinary approaches for the control environmental factors, which may greatly aid in enhancing the prevention and treatment outcome of oral diseases. This Special Issue is open to studies related to oral health, extending to environmental factors in the etiology of oral diseases. Papers, particularly those addressing strategies to improve the use of antimicrobials or prevent and control the emergence of resistance, are invited.

Prof. Dr. Mohammad Amjad Kamal
Guest Editor

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