Gram-Negative Bloodstream Infections

Dear Colleagues,

This special issue aims to highlight the recent advancements in the pathogenesis, epidemiology, diagnosis, and antimicrobial management of Gram-negative bloodstream infections. The morbidity and mortality of Gram-negative bloodstream infections have heavy burden on the general public and special populations such as immune compromised hosts. Changing epidemiology of antimicrobial resistance among Gram-negative bloodstream isolates emphasizes the dynamic interactions between hospitals and the community. Increasing antimicrobial resistance rates limit both empirical and definitive antimicrobial treatment options. Utilization of novel antimicrobial agents and cutting-edge treatment strategies through experimental and clinical therapeutics may improve clinical outcomes and advance this filed. Evolution of rapid diagnostics for early identification of bloodstream isolates as well as genotypic and phenotypic antimicrobial susceptibility testing provide opportunities for clinicians and researchers and hope for patients in a better future.   

Prof. Majdi N. Al-Hasan
Guest Editor

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