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Mapping Anti-HLA Class I Cross-Reactivity for Transplantation Using Interpretable Embedding and Clustering of SAB MFI
- Luis Ramalhete,
- Rúben Araújo,
- Cristiana Teixeira,
- Isaias Pedro,
- Isabel Silva and
- Anibal Ferreira
Background: Mapping anti–HLA class I cross-reactivity from single-antigen bead (SAB) mean fluorescence intensity (MFI) data supports donor selection. However, interpretation is complicated by analytical choices and assay variability. Methods: A...
