You are currently viewing a new version of our website. To view the old version click .

Most Recent

  • Article
  • Open Access

Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology

  • Shaimaa R. Ahmed,
  • Hanan Khojah,
  • Maram Aldera,
  • Jenan Alsarah,
  • Dai Alwaghid,
  • Luluh Hamdan,
  • Hadeel Aljuwair,
  • Manal Alshammari,
  • Hanadi Albalawi and
  • Reema Aldekhail
  • + 2 authors
Int. J. Mol. Sci.2026, 27(1), 277;https://doi.org/10.3390/ijms27010277 
(registering DOI)

26 December 2025

Opophytum forskahlii has a well-established ethnopharmacological significance. This study aimed to assess the skin anti-aging and hair growth-promoting activities of O. forskahlii seed oil (OFSO) and the underlying mechanism. GC-MS profiling revealed...

  • Article
  • Open Access
Int. J. Mol. Sci.2026, 27(1), 276;https://doi.org/10.3390/ijms27010276 
(registering DOI)

26 December 2025

The non-absorbability and biological inertia of traditional bone wax often result in foreign body retention, inhibit bone healing, and increase the risk of infection. Herein, a novel absorbable bone wax was developed by mixing polyethylene glycol (PE...

  • Brief Report
  • Open Access

Expression of Serum and Exosomal microRNA-34a in Subjects with Increased Fat Mass

  • Jacqueline Alejandra Noboa-Velástegui,
  • Rodolfo Iván Valdez-Vega,
  • Jorge Castro-Albarran,
  • Perla Madrigal-Ruiz,
  • Ana Lilia Fletes-Rayas,
  • Sandra Luz Ruiz-Quezada,
  • Martha Eloisa Ramos-Márquez,
  • José de Jesús López-Jiménez,
  • Iñaki Álvarez and
  • Rosa Elena Navarro-Hernández
Int. J. Mol. Sci.2026, 27(1), 270;https://doi.org/10.3390/ijms27010270 
(registering DOI)

26 December 2025

Extracellular vesicles (EVs), particularly exosomes, are key mediators of intercellular communication, transporting biomolecules such as nucleic acids, lipids, and proteins that influence immune and metabolic pathways. In adipose tissue (AT), adipocy...

  • Article
  • Open Access

A Combined Bioinformatics and Clinical Validation Study Identifies MDM2, FKBP5 and CTNNA1 as Diagnostic Gene Signatures for COPD in Peripheral Blood Mononuclear Cells

  • Innokenty A. Savin,
  • Aleksandra V. Sen’kova,
  • Andrey V. Markov,
  • Olga S. Kotova,
  • Ilya S. Shpagin,
  • Lyubov A. Shpagina,
  • Valentin V. Vlassov and
  • Marina A. Zenkova
Int. J. Mol. Sci.2026, 27(1), 273;https://doi.org/10.3390/ijms27010273 
(registering DOI)

26 December 2025

Chronic obstructive pulmonary disease (COPD) is often diagnosed after significant lung damage has already occurred, highlighting a need for minimally invasive biomarkers for early detection of COPD development. This study aims to identify transcripti...

  • Case Report
  • Open Access

Coexistence of Alport Syndrome and Fabry Disease in a Female with R112H Variant: Early Progression of Fabry

  • Amedeo Grimaldi,
  • Alessandra Auletta,
  • Francesca Ciurli,
  • Valeria Aiello,
  • Gisella Vischini,
  • Benedetta Fabbrizio,
  • Francesca Becherucci,
  • Gianandrea Pasquinelli,
  • Gaetano La Manna and
  • Irene Capelli
  • + 1 author
Int. J. Mol. Sci.2026, 27(1), 269;https://doi.org/10.3390/ijms27010269 
(registering DOI)

26 December 2025

Fabry disease (FD) is an X-linked lysosomal disorder caused by GLA mutations, typically associated with glycosphingolipid accumulation and a wide phenotypic spectrum. The p.R112H variant is generally linked to a non-classic predominantly renal phenot...

  • Article
  • Open Access
Int. J. Mol. Sci.2026, 27(1), 272;https://doi.org/10.3390/ijms27010272 
(registering DOI)

26 December 2025

The role of alternative nucleic acid structures (ANS) in biology is an area of increasing interest. These non-canonical structures include the Z-DNA and Z-RNA duplexes (ZNA), the three-stranded triplex, the four-stranded G-quadruplex (GQ), and i-moti...

  • Review
  • Open Access
Int. J. Mol. Sci.2026, 27(1), 263;https://doi.org/10.3390/ijms27010263 
(registering DOI)

26 December 2025

Moringa oleifera, widely recognized as the horseradish tree or drumstick tree, is classified within the Moringaceae family, which comprises 13 species predominantly distributed across tropical and subtropical regions. The plant possesses a variety of...

  • Review
  • Open Access

Dopamine and the Gut Microbiota: Interactions Within the Microbiota–Gut–Brain Axis and Therapeutic Perspectives

  • Aurelia Cristiana Barbu,
  • Smaranda Stoleru,
  • Aurelian Zugravu,
  • Elena Poenaru,
  • Adrian Dragomir,
  • Mihnea Costescu,
  • Sorina Maria Aurelian,
  • Yara Shhab,
  • Clara Maria Stoleru and
  • Oana Andreia Coman
  • + 1 author
Int. J. Mol. Sci.2026, 27(1), 271;https://doi.org/10.3390/ijms27010271 
(registering DOI)

26 December 2025

The microbiota–gut–brain axis (MGBA) comprises a complex bidirectional communication network integrating neural, immune, metabolic, and endocrine pathways. Dopamine, traditionally viewed as a central neurotransmitter, also plays essential...

  • Review
  • Open Access

Insights into the Complex Biological Network Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

  • Dobrina Dudova,
  • Martina Bozhkova,
  • Steliyan Petrov,
  • Ralitsa Nikolova,
  • Teodora Kalfova,
  • Mariya Ivanovska,
  • Katya Vaseva,
  • Maria Nikolova and
  • Ivan N. Ivanov
Int. J. Mol. Sci.2026, 27(1), 268;https://doi.org/10.3390/ijms27010268 
(registering DOI)

26 December 2025

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder characterized by immune dysregulation, metabolic impairments, neuroendocrine disturbances, endothelial dysfunction, and gastrointestinal abnormalities....

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Int. J. Mol. Sci. - ISSN 1422-0067