Journal History
| 2000 | The inaugural issue was released. IJMS was published as a quarterly journal. |
| 2003 | IJMS adopted a monthly publication schedule. |
| 2004 | IJMS was indexed in Science Citation Index Expanded (SCIE)—Web of Science (Clarivate Analytics), starting with Volume 5 (Issue 1). |
| 2005 | IJMS received its first Impact Factor (1.467). |
| 2007 | IJMS established the following sections:
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| 2008 | MDPI joined CrossRef and started assigning DOI numbers to each paper published in the IJMS. All papers from this year on were released under the Creative Commons (CC-BY) license. IJMS was archived in PubMed Central (PMC) and indexed in PubMed. |
| 2009 | IJMS published its 500th paper. IJMS established the following sections:
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| 2010 | IJMS published its 1,000th paper. |
| 2014 | IJMS published its 5,000th paper. |
| 2015 | IJMS established the section Bioinorganic Chemistry. |
| 2016 | IJMS established the following sections:
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| 2017 | IJMS published its 10,000th paper. IJMS held its first physical meeting, the 2nd ISFMS: Non-Coding RNAs and Epigenetics in Cancer, in Basel, Switzerland, from 21 to 23 June 2017. IJMS rearranged the sections as following:
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| 2018 | IJMS established the following sections:
The Epigenetics Society (ES) became affiliated to IJMS. |
| 2019 | IJMS adopted a semi-monthly publication schedule. IJMS established the section Molecular Role of Xenobiotics (discontinued later). IJMS published its 20,000th paper. The European Calcium Society (ECS) (stopped cooperation in February 2025) became affiliated to IJMS. The European Chitin Society (EUCHIS) became affiliated to IJMS. The Signal Transduction Society (STS) (stopped cooperation in May 2023) became affiliated to IJMS. The Spanish Society for Cell Biology (SEBC) became affiliated to IJMS. IJMS held the 3rd ISFMS: RNA Regulatory Networks, in Lisbon, Portugal, from 26 to 28 June 2019. |
| 2021 | The Biomedical Research Centre (CIBM) became affiliated to IJMS. The British Neuro-Oncology Society (BNOS) became affiliated to IJMS. |
| 2022 | IJMS established the section Molecular Nanoscience. IJMS held the 4th ISFMS: Biochemistry, Molecular Biology and Druggability of Proteins, in Florence, Italy, from 6 to 9 September, 2022. The Italian Society of Food Sciences (SISA) became affiliated to IJMS. |
| 2025 | IJMS published its 100,000th paper. IJMS held the 5th ISFMS: Molecular Regulatory Mechanisms of Biological Function and Drug Discovery Based on Protein Structure/Function Analysis, in Kyoto, Japan, from 26 to 29 August, 2025. |
| 2026 | IJMS received its 2025 Impact Factor (5.6), ranked 72/328 (Q1) in "Biochemistry & Molecular Biology". IJMS received its 2025 CiteScore (10.0), ranked 66/414 (Q1) in "Molecular Biology". |
Editor-in-Chief
| 2000–2001 | Editor-in-Chief: Prof. Dr. Jerzy Leszczynski (Founding Editor) |
| 2004 | Editor-in-Chief: Dr. Francis F. Muguet |
| 2005 | Editor-in-Chief: Dr. Shu-Kun Lin |
| 2006–2007 | Editor-in-Chief: Prof. Dr. Claude A. Daul |
| 2017–2026 | Editor-in-Chief: Prof. Dr. Maurizio Battino |
| 2026–present | Editor-in-Chief: Prof. Dr. José L. Quiles |
Section Editor-in-Chief
| 2007 | Section Editor-in-Chief: Prof. Dr. Claude A. Daul for the section on Physical Chemistry, Theoretical and Computational Chemistry Section Editor-in-Chief: Prof. Dr. Andreas Taubert for the section on Material Sciences and Nanotechnology |
| 2007–2009 | Section Editor-in-Chief: Prof. Dr. Michael N. Hall for the section on Biochemistry, Molecular Biology and Biophysics |
| 2008 | Section Editor-in-Chief: Dr. Claire Hellio for the section on Green Chemistry Section Editor-in-Chief: Prof. Dr. Kurt A. Jellinger for the section on Molecular Pathology Section Editor-in-Chief: Prof. Dr. Ian A. Nicholls for the section on Molecular Recognition |
| 2009 | Section Editor-in-Chief: Prof. Dr. Mark L. Richter for the section on Muscle Contraction Section Editor-in-Chief: Prof. Dr. Stephen A. Bustin for the section on Molecular Diagnostics |
| 2009–2011 | Section Editor-in-Chief: Prof. Dr. Mark Cronin for the section on Molecular Toxicology |
| 2010–2011 | Section Editor-in-Chief: Dr. Andrei Alexandrescu for the section on Biochemistry, Molecular Biology and Biophysics |
| 2011–2024 | Section Editor-in-Chief: Prof. Dr. Charles Brennan for the section on Bioactives and Nutraceuticals |
| 2012–2014 | Section Editor-in-Chief: Professor Roger A. Coulombe, Jr. for the section on Molecular Toxicology |
| 2012–2016 | Section Editor-in-Chief: Dr. Michael Iba for the section on Molecular Toxicology Section Editor-in-Chief: Prof. Dr. Mark L. Richter for the section on Biochemistry, Molecular Biology and Biophysics |
| 2017 | Section Editor-in-Chief: Prof. Dr. Claire Hellio for the section on Biochemistry, Molecular and Cellular Biology |
| 2017–2023 | Section Editor-in-Chief: Prof. Dr. Guido R.M.M. Haenen for the section on Molecular Toxicology |
| 2017–2026 | Section Editor-in-Chief: Prof. Dr. Maurizio Battino for the section on Bioactives and Nutraceuticals |
| 2017–present | Section Editor-in-Chief: Prof. Dr. Kurt A. Jellinger for the section on Molecular Pathology, Diagnostics, and Therapeutics” Section Editor-in-Chief: Prof. Dr. Stephen Bustin for the section on Molecular Pathology, Diagnostics, and Therapeutics Section Editor-in-Chief: Prof. Dr. Xiaofeng Jia for the section on Molecular Pathology, Diagnostics, and Therapeutics Section Editor-in-Chief: Prof. Dr. Andreas Taubert for the section on Biomaterial Sciences Section Editor-in-Chief: Prof. Dr. Ian A. Nicholls for the section on Molecular Biophysics |
| 2018–2023 | Section Editor-in-Chief: Prof. Dr. Paschalis Alexandridis for the section on Physical Chemistry and Chemical Physics |
| 2018–2026 | Section Editor-in-Chief: Prof. Dr. Claudiu T. Supuran for the section on Biochemistry |
| 2018–present | Section Editor-in-Chief: Prof. Dr. Antonio Rescifina for the section on Molecular Informatics Section Editor-in-Chief: Prof. Dr. Jeffrey L. Platt for the section on Molecular Immunology |
| 2019–2022 | Section Editor-in-Chief: Prof. Dr. Michael Welsh for the section on Molecular Oncology Section Editor-in-Chief: Prof. Dr. José L. Quiles for the section on Molecular Role of Xenobiotics |
| 2019–2023 | Section Editor-in-Chief: Prof. Dr. Maurizio Margaglione for the section on Molecular Genetics and Genomics |
| 2019–2026 | Section Editor-in-Chief: Prof. Dr. Andreas Burkovski for the section on Molecular Microbiology |
| 2019–present | Section Editor-in-Chief: Prof. Dr. Antonio Pisani for the section on Molecular Neurobiology Section Editor-in-Chief: Prof. Dr. Dongho Kim for the section on Physical Chemistry and Chemical Physics |
| 2020–2021 | Section Editor-in-Chief: Prof. Dr. Bamin Khomami for the section on Macromolecules |
| 2020–2022 | Section Editor-in-Chief: Dr. Eric Vallender for the section on Molecular Genetics and Genomics |
| 2021–2023 | Section Editor-in-Chief: Dr. Manfredi Rizzo for the section on Molecular Endocrinology and Metabolism |
| 2022–present | Section Editor-in-Chief: Prof. Dr. Yuri Lyubchenko for the section on Molecular Nanoscience Section Editor-in-Chief: Dr. José L. Quiles for the section on Molecular Endocrinology and Metabolism |
| 2023–present | Section Editor-in-Chief: Dr. Giovanni Malerba for the section on Molecular Genetics and Genomics |
| 2024–present | Section Editor-in-Chief: Dr. João Pedro Silva for the section on Molecular Toxicology |
| 2025–present | Section Editor-in-Chief: Prof. Dr. Burkhard Poeggeler for the section on Molecular Pharmacology |
| 2026–present | Section Editor-in-Chief: Prof. Dr. Nobuyuki Takahashi for the section on Bioactives and Nutraceuticals Section Editor-in-Chief: Prof. Dr. Yoshinori Marunaka for the section on Biochemistry Section Editor-in-Chief: Prof. Dr. Hao Lin for the section on Molecular Informatics Section Editor-in-Chief: Prof. Dr. Vishwanath Venketaraman for the section on Molecular Microbiology |

