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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosing, Treating, and Preventing Eye Diseases

edited by Ermete Giancipoli

submission deadline 16 Apr 2026 | 4 articles | Viewed by 6939 | Submission Open

Keywords: retinal disease; vitreoretinal surgery; cataract surgery; intraocular lens; cornea; glaucoma; neuro-ophthalmology; multimodal imaging; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Image Analysis and Machine Learning

edited by

Inzamam Nasir

and

Costin Teodor Streba

submission deadline 21 Apr 2026 | 7 articles | Viewed by 6580 | Submission Open

Keywords: AI-enhanced clinical imaging workflows; deep learning for disease classification and segmentation; radiomics and multi-omics integration; federated learning and privacy-preserving analytics; next-generation medical image annotation techniques; explainable AI in diagnostic imaging; high-throughput screening in digital pathology; cross-domain adaptation and transfer learning in healthcare; prognostic and predictive imaging biomarkers; clinical decision support systems using machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Prognosis and Management of Breast Cancer

edited by

Marko Spasic

submission deadline 21 Apr 2026 | 6 articles | Viewed by 3261 | Submission Open

Keywords: breast cancer; diagnostics; personalized medicine; breast surgery; individualized treatment; radiotherapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Progress in Gynecologic Oncology

edited by

Antoni Llueca

submission deadline 21 Apr 2026 | 2 articles | Viewed by 1472 | Submission Open

Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Insights in Dental Diagnostics, Biomaterials and Digital Workflow

edited by

Marina Meleșcanu Imre

and

Ana Maria Cristina Țâncu

submission deadline 21 Apr 2026 | 1 articles | Viewed by 486 | Submission Open

Keywords: dental diagnostics; artificial intelligence (AI); digital dentistry; biomaterials; 3D printing; intraoral scanning; CAD/CAM; digital workflow; predictive analytics; clinical innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in the Emergency and Critical Care Medicine

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 16 articles | Viewed by 52963 | Submission Open

Keywords: diagnostics; emergency and critical care medicine; trauma; anesthesiology; respiratory failure; sepsis; cardiovascular disease; healthcare-associated infection prevention; end-of-life care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Diagnostic and Testing Strategies for Infectious Diseases

edited by

Fernanda De-Paris

submission deadline 30 Apr 2026 | 9 articles | Viewed by 38755 | Submission Open

Keywords: infectious diseases diagnosis; clinical laboratory techniques; molecular biology; infection control; virulence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Prognosis of Sepsis

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 8 articles | Viewed by 30351 | Submission Open

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging in Gastrointestinal and Liver Diseases

edited by

Ruxandra Mare

and

Ioan Sporea

submission deadline 30 Apr 2026 | 9 articles | Viewed by 23806 | Submission Open

Keywords: ultrasonography; elastography; multiparametric ultrasound; contrast-enhanced ultrasound; endoscopic ultrasound; contrast-enhanced endoscopic ultrasound; computer tomography; magnetic resonance imaging; gastrointestinal diseases; diffuse liver disease; focal liver lesions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Latest News in Digital Pathology

edited by Tahir Mahmood

submission deadline 30 Apr 2026 | 6 articles | Viewed by 19845 | Submission Open

Keywords: digital pathology; generative AI; cancer diagnosis; cancer prognosis; imaging modalities; cancer grading; artificial intelligence in pathology; histopathology; image analysis; medical imaging; vision-language models in histopathology; large language models for pathology diagnostics; multimodal AI integration in digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnosis and Management of Musculoskeletal Disorders

edited by

Antonio Jesús Láinez-Ramos-Bossini

and Fernando Ruiz Santiago

submission deadline 30 Apr 2026 | 10 articles | Viewed by 14572 | Submission Open

Keywords: musculoskeletal disorder; radiology; interventional procedure; surgery; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in the Diagnosis and Management of Respiratory Diseases

edited by Elio Antonucci

submission deadline 30 Apr 2026 | 5 articles | Viewed by 14543 | Submission Open

Keywords: respiratory disease diagnosis; advanced diagnostic techniques; respiratory management strategies; therapeutic innovations; pulmonary pathophysiology; chronic obstructive pulmonary disease (COPD); asthma management; interstitial lung diseases; respiratory infection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Exploring the Role of Diagnostic Biochemistry, 2nd Edition

edited by Daria Pašalić and Lidija Bilic-Zulle

submission deadline 30 Apr 2026 | 4 articles | Viewed by 11852 | Submission Open

Keywords: laboratory tests in diagnosis; prognosis; monitoring; and treatment; blood biomarkers in laboratory medicine; extravascular body fluid biomarkers in laboratory medicine; novel biomarkers in clinical biochemistry; evidence-based laboratory medicine; extra analytical phases and patient safety; quality assurance and management in laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Diagnosis and Management of Sleep Disorders

edited by Rayleigh Ping Ying Chiang

submission deadline 30 Apr 2026 | 3 articles | Viewed by 11438 | Submission Open

Keywords: sleep disorders; obstructive sleep apnea; diagnosis; causes; symptoms

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Modern Diabetes Diagnosis and Treatment Technology

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 30 Apr 2026 | 5 articles | Viewed by 10270 | Submission Open

Keywords: diabetes; complications; diagnosis; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; technology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Elastography for Applications in Rehabilitation, Physiotherapy, and Sports Sciences

edited by

Juan Antonio Valera-Calero

and

Sandra Sanchez-Jorge

submission deadline 30 Apr 2026 | 3 articles | Viewed by 8748 | Submission Open

Keywords: elastography; shear wave elastography; ultrasound imaging; physiotherapy; rehabilitation; musculoskeletal system

(This special issue belongs to the Section Medical Imaging and Theranostics)

Expanding Horizons in Fascial Diagnostics and Interventions

edited by

Stanley K. H. Lam

and Bradley Dean Fullerton

submission deadline 30 Apr 2026 | 2 articles | Viewed by 8658 | Submission Open

Keywords: ultrasound imaging; fascial pathologies; musculoskeletal function; fascial disorders; ultrasound-guided interventions; musculoskeletal care

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI-Powered Solutions for Personalized Healthcare Monitoring with Wearables

edited by Kuo-Chung Chu,

Jakir Hossain Bhuiyan Masud

and Ming-Chun Huang

submission deadline 30 Apr 2026 | 5 articles | Viewed by 6621 | Submission Open

Keywords: artificial intelligence; wearable technology; health monitoring; remote patient care; personalized healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Skin Disorders 2025

edited by Neil K. Jairath

submission deadline 30 Apr 2026 | 3 articles | Viewed by 6554 | Submission Open

Keywords: artificial intelligence; dermatology; computer vision; machine learning; deep neural networks; large language models; personalized medicine; predictive analytics; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Spinal Diseases

edited by Jwo-Luen Pao

submission deadline 30 Apr 2026 | 4 articles | Viewed by 6497 | Submission Open

Keywords: spinal diseases; spinal conditions; endoscopy; artificial intelligence (AI); radiological techniques; MRI; CT scans; X-rays; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Role of Endoscopic Ultrasound in Clinical Medicine

edited by

Germana De Nucci

submission deadline 30 Apr 2026 | 3 articles | Viewed by 6371 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic imaging; fine needle aspiration (FNA); contrast-enhanced EUS; elastography techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Craniofacial Practices: Imaging, AI, Surgery, and Patient Care

edited by

Rami R. Hallac

submission deadline 30 Apr 2026 | 5 articles | Viewed by 6355 | Submission Open

Keywords: craniofacial imaging; 3D radiological imaging; 3D photogrammetry; 4D stereophotogrammetry; artificial intelligence (AI); craniofacial surgery; patient-centered care; 3D printing; precision medicine; telehealth; surgical planning; interdisciplinary collaboration

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Approach and Innovations in the Different Dentistry Fields, 2nd Edition

edited by

Francesco Inchingolo

Giuseppina Malcangi

Gianna Dipalma

Angelo Michele Inchingolo

and

Ioana Roxana Bordea

submission deadline 30 Apr 2026 | 5 articles | Viewed by 5670 | Submission Open

Keywords: diagnosis; oral surgery; implantology; orthodontic; endodontic; oral health; orthodontic diseases and innovation; tissue regeneration; reconstructive surgical procedures; tissue engineering; biomedical engineering; stem cells regeneration tissue; oral surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Interventional Pulmonology

edited by George A. Eapen

submission deadline 30 Apr 2026 | 6 articles | Viewed by 5342 | Submission Open

Keywords: interventional pulmonology; minimally invasive procedures; pulmonary diagnostics; bronchoscopy; lung cancer; advanced imaging modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Brain MRI: Current Development and Applications

edited by

Hung-Chieh Chen

submission deadline 30 Apr 2026 | 3 articles | Viewed by 5129 | Submission Open

Keywords: neuroimaging; diagnostic MRI; artificial intelligence; neurological disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition

edited by

Silvia Martu

Liliana-Georgeta Foia

and

Maria Alexandra Mârțu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 4933 | Submission Open

Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence and Computational Methods in Cardiology 2026

edited by Farhad Fathieh and Guennadi Saiko

submission deadline 30 Apr 2026 | 4 articles | Viewed by 4620 | Submission Open

Keywords: artificial intelligence in cardiology; cardiovascular diseases; diagnostics; monitoring and screening; machine/deep learning; innovative medical devices; clinical applications; multimodal medical devices

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Point-of-Care Testing (POCT) for Infectious Diseases

edited by Rongzhang Hao

submission deadline 30 Apr 2026 | 4 articles | Viewed by 4135 | Submission Open

Keywords: point-of-care testing (POCT); microfluidic chip and biosensor; ultrafast detection techniques; AI-integrated testing systems; infectious disease; pathogen

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

AI-Driven Precision Medicine: Innovations in Diagnosis, Prognosis, and Management Response

edited by

Feng Gao

submission deadline 30 Apr 2026 | 5 articles | Viewed by 4050 | Submission Open

Keywords: precision medicine; artificial intelligence; clinical decision support; deep learning; large language models (LLMs); prognosis prediction; medical imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Concepts in Fetal and Placental Pathology

edited by

Ovidiu Simion Cotoi

and

Diana-Maria Chiorean

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3898 | Submission Open

Keywords: fetal pathology; placental pathology; perinatal outcomes; perinatal autopsy; maternal-fetal interface; intrauterine growth restriction; preeclampsia; stillbirth; villitis; chorioamnionitis; histopathology; molecular pathology; case reports

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Non-Invasive Diagnostic Technologies for Heart Diseases

edited by Dentamaro Ilaria

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3488 | Submission Open

Keywords: transthoracic echocardiography; cardiac magnetic resonance; multimodality cardiovascular imaging; cardiac CT; transesophageal echocardiography; cardiovascular disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopy in Gynecology and Gynecologic Oncology

edited by

Rudolf Lampé

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3431 | Submission Open

Keywords: gynecology; endoscopy; operative gynecology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Interventional Radiology in 2025–2026: From Technological Innovation to Clinical Optimization

edited by

Francesco Giurazza

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3367 | Submission Open

Keywords: emergency; oncology; arterial; vascular diseases; extravascular-bleedings; aneurysms; vascular malformations; neurointerventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Epigenetics and Epigenomics: Diagnosis and Prognosis

edited by

Biaoru Li

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3284 | Submission Open

Keywords: epigenetics; epigenomics; diagnosis; prognosis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Infectious Diseases in Obstetrics and Gynecology: Diagnosis and Management

edited by

Edward Araujo Júnior

submission deadline 30 Apr 2026 | 5 articles | Viewed by 3241 | Submission Open

Keywords: infectious diseases; obstetrics; gynecology; diagnosis; management; sexually transmitted diseases; congenital malformations; chronic pelvic pain; infertility

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Management of Dental Medicine and Surgery, 2nd Edition

edited by

José María Martínez González

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3116 | Submission Open

Keywords: oral surgery; oral medicine; implant dentistry; gerontology; bone regeneration; oral rehabilitation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Cardiothoracic and Abdominal Imaging: From CT Innovations to AI Diagnostics

edited by

Tommaso D'Angelo

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3058 | Submission Open

Keywords: cardiothoracic imaging; abdominal imaging; CT technologies; artificial intelligence (AI) in diagnosis; AI-based imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic Techniques and Endoscopic Management for Gastrointestinal Diseases

edited by

Micheal Tadros

submission deadline 30 Apr 2026 | 4 articles | Viewed by 2849 | Submission Open

Keywords: endoscopy; gastrointestinal disease; diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Diagnosis of Colorectal Cancer

edited by

Piero Boraschi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2608 | Submission Open

Keywords: colorectal cancer; metastatic disease; colorectal liver metastases; chemotherapy; surgery; therapeutic response assessment; biomarkers; tumor regression grading; computed tomography; MRI; PET; intraoperative ultrasound; multidisciplinary management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Radiology in Head and Neck Diseases

edited by

Daniel Ginat

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2545 | Submission Open

Keywords: head ; neck ; imaging ; radiology ; magnetic resonance imaging ; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Echocardiography in the Intensive Care Unit

edited by

Carlo Caiati

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2358 | Submission Open

Keywords: echocardiography; intensive care unit (ICU); critical care; cardiac function; coronary artery disease; sepsis; shock

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Biomedical Diagnostics and Analysis 2025

edited by

Prabal Datta Barua

Turker Tuncer

and

Sengul Dogan

submission deadline 30 Apr 2026 | 3 articles | Viewed by 2337 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; medical signal and image processing; internet of medical things (IoMT); bioinformatics; explainable artificial intelligence; machine learning; uncertainty

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 30 Apr 2026 | Viewed by 1948 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome– host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Solutions to Cardiovascular Dilemmas: From Diagnosis to Therapy, Second Edition

edited by

Thach N. Nguyen

and C Michael Gibson

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1667 | Submission Open

Keywords: coronary artery disease; acute coronary syndrome; heart failure; hemodynamics in heart failure; coronary flow dynamic; dilated cardiomyopathy; valvular disease; atrial fibrillation; sudden cardiac death; syncope; individualized treatment; clinical decision-making; computational fluid dynamic; big data analysis; artificial intelligence; machine learning

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1429 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Multisystem Wilson’s Disease

edited by

Tomasz Litwin

and

Agnieszka Antos

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1128 | Submission Open

Keywords: Wilson’ s disease; brain magnetic resonance imaging; biomarkers; copper metabolism; Wilson’ s disease mimicking disorders; zinc; chelators; liver transplantation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnosis and Management of Breast Cancer

edited by Wing Lok Wendy Chan

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1015 | Submission Open

Keywords: breast cancer; diagnosis; treatment; personalized medicine; imaging techniques; immunotherapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Genomics in Cardiac Diagnostics: Bridging Novel Insights to Clinical Practice

edited by

Yiqing Yang

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1004 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; cardiac arrhythmia; idiopathic cardiomyopathy; coronary heart disease; arterial hypertension; stroke; genetics; genomics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 30 Apr 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis of Viral Respiratory Infections, 2nd Edition

edited by

Federica Novazzi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 699 | Submission Open

Keywords: respiratory tract infections; lower respiratory tract infections (LRTIs); upper respiratory tract infections (URTIs); whole-genome sequencing (WGS); immunological techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

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