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Tropical Medicine and Infectious Disease, Volume 7, Issue 3

2022 March - 17 articles

Cover Story: In addition to the already known variety of dysfunctions of many tissues, new-onset cardiac arrhythmias have emanated, being common during acute SARS-CoV-2 infection, but also in patients with post-COVID-19 syndrome. The occurrence of arrhythmias poses an additional factor worsening the outcome, especially in critically ill patients. Although arrhythmias can arise secondary to hypoxemia/hypoxia and hyperinflammatory response in COVID-19 patients, recent findings show that SARS-CoV-2 can directly infect cardiac conducting cardiomyocytes obtained from the atrioventricular (AV) node, leaving behind a typical immunohistochemical signature. This finding indicates that viral-mediated impairment of the cardiac conduction system could underlie COVID-19-provoked cardiac arrhythmias. View this paper
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Articles (17)

  • Article
  • Open Access
5 Citations
3,786 Views
12 Pages

The Effectiveness of the Use of Regdanvimab (CT-P59) in Addition to Remdesivir in Patients with Severe COVID-19: A Single Center Retrospective Study

  • Ganghee Chae,
  • Aram Choi,
  • Soyeoun Lim,
  • Sooneun Park,
  • Seungjun Lee,
  • Youngick Ahn,
  • Jinhyoung Kim,
  • Seungwon Ra,
  • Yangjin Jegal and
  • Taehoon Lee
  • + 4 authors

Introduction: Coronavirus disease 2019 (COVID-19) still has a high mortality rate when it is severe. Regdanvimab (CT-P59), a neutralizing monoclonal antibody that has been proven effective against mild to moderate COVID-19, may be effective against s...

  • Review
  • Open Access
10 Citations
16,030 Views
28 Pages

The “bench to bedside” (BTB) paradigm of translational medicine (TM) assumes that medical progress emanates from basic science discoveries transforming clinical therapeutic models. However, a recent report found that most published medica...

  • Article
  • Open Access
6 Citations
4,494 Views
14 Pages

Digital Storytelling and Community Engagement to Find Missing TB Cases in Rural Nuh, India

  • Subhi Quraishi,
  • Hilmi Quraishi,
  • Hemlata Yadav,
  • Ayushi Singh,
  • Ilmana Fasih,
  • Nathaly Aguilera Vasquez,
  • Lavanya Huria,
  • Tripti Pande,
  • Olive Mumba and
  • Amera Khan
  • + 1 author

Nuh, Haryana, is one of India’s least developed districts. To improve TB case notifications, ZMQ carried out an active case-finding (ACF) intervention conducted by community health workers (MIRAs) using a digital TB storytelling platform to cre...

  • Review
  • Open Access
34 Citations
7,275 Views
17 Pages

The Biological and Clinical Aspects of a Latent Tuberculosis Infection

  • Nelli F. Khabibullina,
  • Daria M. Kutuzova,
  • Irina A. Burmistrova and
  • Irina V. Lyadova

Tuberculosis (TB), caused by bacilli from the Mycobacterium tuberculosis complex, remains a serious global public health problem, representing one of the main causes of death from infectious diseases. About one quarter of the world’s population...

  • Case Report
  • Open Access
8 Citations
26,952 Views
7 Pages

Malignant Syphilis in a Female Patient: A Case Report and Mini-Review

  • Julija Dimnik,
  • Maja Benko,
  • Violeta Hosta,
  • Andreja Murnik Rauh,
  • Andreja Pagon,
  • Vesna Cvitković Špik,
  • Saba Battelino and
  • Domen Vozel

Malignant syphilis (MS) is a rare form of secondary syphilis with grotesque skin lesions, systemic manifestation and life-threatening complications. This article presents a case of MS in an immunocompetent 41-year-old female, who initially manifested...

  • Article
  • Open Access
7 Citations
4,228 Views
11 Pages

Analysis of Puumala orthohantavirus Genome Variants Identified in the Territories of Volga Federal District

  • Emmanuel Kabwe,
  • Walaa Al Sheikh,
  • Anton F. Shamsutdinov,
  • Ruzilya K. Ismagilova,
  • Ekaterina V. Martynova,
  • Olesia V. Ohlopkova,
  • Yuri A. Yurchenko,
  • Tatiana A. Savitskaya,
  • Guzel S. Isaeva and
  • Yuriy N. Davidyuk
  • + 3 authors

Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease commonly diagnosed in the Volga Federal District (VFD). HFRS is caused by Puumala orthohantavirus (PUUV), and this virus is usually detected in bank voles as its natural host (My...

  • Article
  • Open Access
39 Citations
7,060 Views
25 Pages

The study of the spatial differentiation of COVID-19 in cities and its driving mechanism is helpful to reveal the spatial distribution pattern, transmission mechanism and diffusion model, and evolution mechanism of the epidemic and can lay the founda...

  • Article
  • Open Access
24 Citations
6,529 Views
9 Pages

During the COVID-19 pandemic, an excess of all-cause mortality has been recorded in several countries, including Peru. Most excess deaths were likely attributable to COVID-19. In this study, we compared the excess all-cause mortality and COVID-19 mor...

  • Case Report
  • Open Access
7 Citations
5,413 Views
5 Pages

Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report

  • Hrvoje Jakovac,
  • Antun Ferenčić,
  • Christophe Stemberger,
  • Bojana Mohar Vitezić and
  • Dražen Cuculić

Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio patholo...

  • Article
  • Open Access
33 Citations
5,896 Views
9 Pages

Background: Widespread and rapidly emerging multidrug-resistant uropathogens, particularly carbapenem-resistant pathogens, are a public health concern that impairs the determination of empirical therapy. This study aims to evaluate the antimicrobial...

  • Systematic Review
  • Open Access
9 Citations
6,345 Views
8 Pages

Central nervous system (CNS) infections constitute a life-threatening condition, especially in children. Treatment limitations exist for drug-resistant CNS bacterial infections. Inadequate CNS penetration and intravenous (IV) antibiotic treatment fai...

  • Case Report
  • Open Access
1 Citations
4,009 Views
4 Pages

Whipple’s disease is a rare chronic infection caused by the actinomycete Tropheryma whipplei. Patients commonly present with gastrointestinal symptoms. We present a case of classic Whipple’s disease complicated by a probable Jarisch&ndash...

  • Article
  • Open Access
14 Citations
3,864 Views
9 Pages

Diagnostic Value of Neutrophil-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio, and Platelet-to-Lymphocyte Ratio in the Diagnosis of Erythema Nodosum Leprosum: A Retrospective Study

  • Natalia Tanojo,
  • Damayanti,
  • Budi Utomo,
  • Evy Ervianti,
  • Dwi Murtiastutik,
  • Cita Rosita Sigit Prakoeswa and
  • Muhammad Yulianto Listiawan

Erythema nodosum leprosum (ENL) is an acute immune complex-mediated condition of the dermis, subcutaneous tissue, and other tissues seen in patients with multibacillary (MB) leprosy, causing severe impairment to patients’ quality of life. To date, th...

  • Article
  • Open Access
3 Citations
3,527 Views
12 Pages

Genetic Analysis of Influenza A/H1N1pdm Strains Isolated in Bangladesh in Early 2020

  • Abu Hasan,
  • Tadahiro Sasaki,
  • Juthamas Phadungsombat,
  • Ritsuko Koketsu,
  • Rummana Rahim,
  • Nikhat Ara,
  • Suma Mita Biswas,
  • Riku Yonezawa,
  • Emi E. Nakayama and
  • Tatsuo Shioda
  • + 1 author

Influenza is one of the most common respiratory virus infections. We analyzed hemagglutinin (HA) and neuraminidase (NA) gene segments of viruses isolated from influenza patients who visited Evercare Hospital Dhaka, Bangladesh, in early 2020 immediate...

  • Systematic Review
  • Open Access
19 Citations
5,224 Views
13 Pages

The Use of Proton Pump Inhibitors and COVID-19: A Systematic Review and Meta-Analysis

  • Kaneez Fatima,
  • Talal Almas,
  • Shan Lakhani,
  • Arshia Jahangir,
  • Abdullah Ahmed,
  • Ayra Siddiqui,
  • Aiman Rahim,
  • Saleha Ahmed Qureshi,
  • Zukhruf Arshad and
  • Adeena Musheer
  • + 1 author

COVID-19 has proved to be a serious, and consequential disease that has affected millions of people globally. Previously, the adverse effects of proton pump inhibitors (PPI) have been observed with increasing the risk of pneumonia and COVID-19. This...

  • Article
  • Open Access
2 Citations
4,972 Views
12 Pages

Depriving Out-of-School Children of Deworming Tablets for Soil-Transmitted Helminth Infection in Bangladesh: The Irony of a School-Based Deworming Programme

  • Avijit Saha,
  • Srizan Chowdhury,
  • Edwin Theophilus Goswami,
  • Konica Gop,
  • Ariful Alam,
  • Asadur Rahman and
  • Malabika Sarker

Since 2008, Bangladesh has had a school-based deworming programme to combat soil-transmitted helminth (STH) infection among school-aged children (SACs). Existing programmes have trouble reaching SACs, especially those out-of-school (OSCs). This study...

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Trop. Med. Infect. Dis. - ISSN 2414-6366