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Tropical Medicine and Infectious Disease, Volume 10, Issue 7

July 2025 - 26 articles

Cover Story: Triatoma dimidiata is a major vector of Chagas disease in Mexico. In this study, we report for the first time the presence of the L925I knockdown resistance (kdr) mutation in genetically distinct populations of T. dimidiata from southeastern and southern Mexico. This mutation is associated with pyrethroid resistance, a key challenge in vector control strategies. Our findings highlight the need for molecular surveillance to detect resistance markers and improve the effectiveness of control programs aimed at reducing disease transmission. View this paper
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Articles (26)

  • Case Report
  • Open Access
1,826 Views
8 Pages

Anti-IFN-γ Autoantibody Syndrome Presenting with Disseminated Nontuberculous Mycobacteria Infections: A Case Series of Therapeutic Implications and Review of Literature

  • Brooke Cheng,
  • Barinder Bajwa,
  • Seungwon Choi,
  • Hannah Martin,
  • Tyson Miao,
  • Denise Werry,
  • Michael Perlman and
  • Yazdan Mirzanejad

Anticytokine autoantibodies (AAbs), particularly anti-interferon-gamma (anti-IFN-γ) AAbs, disrupt cytokine functions, leading to infections, autoimmune-like diseases, and conditions resembling interleukin-12 (IL-12)/IFN-γ pathway defects....

  • Article
  • Open Access
909 Views
15 Pages

Investigation of the Prevalence of High-Risk Human Papillomavirus, Human Herpesvirus-8, and Herpes Simplex Virus-2 in Cervical Biopsy Samples Using the Real-Time PCR Method

  • Ayfer Bakır,
  • Betül Yüzügüldü,
  • Eylül Beren Tanık,
  • Muhammed Furkan Kürkçü,
  • Gizem Korkut and
  • Firdevs Şahin Duran

Persistent high-risk human papillomavirus (HR-HPV) infection is closely associated with the development of cervical intraepithelial neoplasia (CIN) and cervical cancer. In recent years, the potential impact of viral co-infections on this process has...

  • Editorial
  • Open Access
1,220 Views
5 Pages

Leishmaniasis: Vector–Host–Pathogen Interactions in Health and Disease

  • Pedro Cecilio,
  • Manuela da Silva Solcà and
  • Nuno Santarém

Leishmaniases comprise a group of diseases caused by protozoan parasites belonging to different species of the genus Leishmania; of note; in humans, leishmaniasis presents as a spectrum of clinical syndromes, with the visceral, cutaneous, and mucosal...

  • Article
  • Open Access
1,048 Views
16 Pages

Impact of Nutritional Counselling and Support on Body Mass Index Recovery and Treatment Outcomes Among Tuberculosis Patients in the Lao People’s Democratic Republic

  • Donekham Inthavong,
  • Hend Elsayed,
  • Phonesavanh Keonakhone,
  • Vilath Seevisay,
  • Somdeth Souksanh,
  • Sakhone Suthepmany,
  • Misouk Chanthavong,
  • Xaysomvang Keodavong,
  • Phonesavanh Kommanivanh and
  • Phitsada Siphanthong
  • + 7 authors

Tuberculosis (TB) and undernutrition are intricately linked, significantly impacting health outcomes. However, nutritional support for TB patients is not systematically implemented in Lao People’s Democratic Republic (Lao PDR). This study evalu...

  • Article
  • Open Access
1,324 Views
19 Pages

Epidemiological Profile and Risk Factors for Malaria in Rural Communities Before the Operationalization of the Singrobo–Ahouaty Dam, Southern Côte d’Ivoire

  • Taki Jean Deles Avenié,
  • Kigbafori Dieudonné Silué,
  • Négnorogo Guindo-Coulibaly,
  • Naférima Koné,
  • Sadikou Touré,
  • Kouamé Laurent Valian,
  • Kouassi Séraphin Kouadio,
  • Alloua Marie Joelle Bédia,
  • Boza Fulgence Déabo and
  • Klotcholman Diabagaté
  • + 2 authors

Malaria remains a major public health issue, especially near hydroelectric dams that often promote mosquito breeding. This study aimed to establish baseline epidemiological data during the construction of the Singrobo–Ahouaty dam to support ass...

  • Review
  • Open Access
1 Citations
3,320 Views
14 Pages

Is Ghana Prepared for Another Arboviral Outbreak? Evaluating the 2024 Dengue Fever Outbreak in the Context of Past Yellow Fever, Influenza, and COVID-19 Outbreaks

  • Godfred Amoah Appiah,
  • Jerry John Babason,
  • Anthony Yaw Dziworshie,
  • Abigail Abankwa and
  • Joseph Humphrey Kofi Bonney

Arboviruses are a growing concern in many nations. Several reports of arboviral outbreaks have been recorded globally in the past decade alone. Repeated arboviral outbreaks in developing countries have consistently highlighted vulnerabilities in dise...

  • Article
  • Open Access
1 Citations
1,392 Views
16 Pages

Acute Immunological Biomarkers for Predicting Chronic Rheumatologic Disease After Chikungunya Virus Infection

  • Anyela Lozano-Parra,
  • Víctor Herrera,
  • Luis Ángel Villar,
  • Silvio Urcuqui-Inchima,
  • Juan Felipe Valdés-López and
  • Elsa Marina Rojas Garrido

Early biomarkers are needed to predict the long-term persistence of rheumatical symptoms in patients infected with Chikungunya virus (CHIKV). This nested case-control study aimed to assess immunological factors during the early phases of CHIKV infect...

  • Article
  • Open Access
1 Citations
958 Views
16 Pages

Series 2: Development of a Multiplex Amplicon Next Generation Sequencing Assay for Rapid Assessment of Resistance-Associated Mutations in M. tuberculosis Clinical Cases

  • Adriana Cabrera,
  • Tracy Lee,
  • Kathleen Kolehmainen,
  • Trevor Hird,
  • Danielle Jorgensen,
  • Calvin Ka-Fung Lo,
  • Hasan Hamze,
  • Alan O’Dwyer,
  • Dan Fornika and
  • Rupinder Kaur KhunKhun
  • + 5 authors

Treatment of Mycobacterium tuberculosis requires multi-drug regimens, and resistance to any individual antibiotic can compromise outcomes. For slow-growing organisms like M. tuberculosis, rapid detection of resistance-conferring mutations enables tim...

  • Review
  • Open Access
2 Citations
963 Views
15 Pages

Background: This study intended to fully assess the predictive efficiency of different clinical laboratory parameters for the mortality risk in severe fever with thrombocytopenia syndrome (SFTS). Methods: We systematically searched the Web of Science...

  • Article
  • Open Access
1,131 Views
18 Pages

Series 1: The Use of hsp65- and erm(41)-Targeted Amplicon Sequencing in the Diagnostic Workflow for Non-Tuberculous Mycobacteria

  • Tracy Lee,
  • Adriana Cabrera,
  • Kathleen Kolehmainen,
  • Trevor Hird,
  • Danielle Jorgensen,
  • Alan O’Dwyer,
  • Dan Fornika,
  • Rupinder Kaur KhunKhun,
  • Mabel Rodrigues and
  • Natalie Prystajecky
  • + 3 authors

Evolving technologies available to clinical laboratories and laboratory-related updates to clinical guidelines both drive the need for clinical laboratories to keep their test menu updated and in line with current technological and clinical developme...

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Trop. Med. Infect. Dis. - ISSN 2414-6366