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Gels, Volume 8, Issue 3

2022 March - 58 articles

Cover Story: The clinical use of human MSCs expanded on conventional microcarriers is hampered by their separation from the carrier and undesirable phenotypic changes. In this work, a tissue construct was developed for articular cartilage regeneration (ACR) based on human MSCs expanded on adult or fetal decellularized bovine articular cartilage microgels (CMGs) that do not require cell separation. In this approach, fetal or adult bovine articular cartilage was minced, decellularized, freeze-dried, ground, and sieved to produce CMGs. MSCs were subsequently expanded on CMGs to generate hMSC-loaded CMG microgels (CMG-MSCs). Then, the CMG-MSCs were suspended in sodium alginate, injected, and crosslinked to form an injectable cellular construct for ACR. The constructs showed superior chondrogenesis in vitro compared to MSCs directly encapsulated in an alginate gel. View this paper
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Articles (58)

  • Article
  • Open Access
20 Citations
5,150 Views
13 Pages

26 February 2022

Mechanically enhanced gelatin-based composite hydrogels were developed in the presence of functionalized cellulose nanocrystals (CNCs) employing microbial transglutaminase (mTG) as a binding agent. In this work, the surfaces of CNCs were grafted with...

(This article belongs to the Special Issue Advanced Hydrogels for Biomedical Applications)
  • Article
  • Open Access
35 Citations
4,372 Views
24 Pages

25 February 2022

Geopolymer gel that possesses advantageous features of fast setting, high strength, and good durability is increasingly used in civil engineering, including rapid retrofit projects, roadway, and other construction projects. Furthermore, geopolymer ge...

(This article belongs to the Special Issue Geopolymer Gels for Next-Generation Construction)
  • Article
  • Open Access
7 Citations
10,817 Views
14 Pages

Stability of Paracetamol Instant Jelly for Reconstitution: Impact of Packaging, Temperature and Humidity

  • Samah Hamed Almurisi,
  • Khater AL-Japairai,
  • Farhan Alshammari,
  • Fawaz Alheibshy,
  • Rana M.F. Sammour and
  • Abd Almonem Doolaanea

25 February 2022

The stability of the medicinal product is a major concern in the pharmaceutical industry and health authorities, whose goal is to guarantee that drugs are delivered to patients without loss of therapeutic properties. This study aims to evaluate the e...

  • Article
  • Open Access
45 Citations
7,882 Views
19 Pages

PVA-Based Hydrogels Loaded with Diclofenac for Cartilage Replacement

  • Ana C. Branco,
  • Andreia S. Oliveira,
  • Inês Monteiro,
  • Pedro Nolasco,
  • Diana C. Silva,
  • Célio G. Figueiredo-Pina,
  • Rogério Colaço and
  • Ana P. Serro

24 February 2022

Polyvinyl alcohol (PVA) hydrogels have been widely studied for cartilage replacement due to their biocompatibility, chemical stability, and ability to be modified such that they approximate natural tissue behavior. Additionally, they may also be used...

(This article belongs to the Special Issue Advanced Hydrogels for the Repair of Cartilage Defects)
  • Article
  • Open Access
20 Citations
4,097 Views
11 Pages

Relation between Morphology and Porous Structure of SAPO-11 Molecular Sieves and Chemical and Phase Composition of Silicoaluminophosphate Gels

  • Marat R. Agliullin,
  • Roman E. Yakovenko,
  • Yury G. Kolyagin,
  • Dmitry V. Serebrennikov,
  • Farkhad S. Vildanov,
  • Tatyana R. Prosochkina and
  • Boris I. Kutepov

24 February 2022

The formation of silicoaluminophosphate gels using boehmite, Al isopropoxide, and di-n-propylamine as a template of silicoaluminophosphate gels as well as their subsequent crystallization into SAPO-11 molecular sieves was studied in detail using X-ra...

  • Article
  • Open Access
34 Citations
6,965 Views
15 Pages

23 February 2022

A simple heat treatment method was used to optimize the three-dimensional network structure of the hydrophobic aerogel, and during the heat treatment process at 200–1000 °C, the thermal conductivity of the aerogel reached the lowest to 0.02...

(This article belongs to the Special Issue Preparation and Application of Aerogel and its Composite Materials)
  • Review
  • Open Access
32 Citations
6,941 Views
18 Pages

Cellulosic-Based Conductive Hydrogels for Electro-Active Tissues: A Review Summary

  • Esubalew Kasaw Gebeyehu,
  • Xiaofeng Sui,
  • Biruk Fentahun Adamu,
  • Kura Alemayehu Beyene and
  • Melkie Getnet Tadesse

23 February 2022

The use of hydrogel in tissue engineering is not entirely new. In the last six decades, researchers have used hydrogel to develop artificial organs and tissue for the diagnosis of real-life problems and research purposes. Trial and error dominated th...

(This article belongs to the Special Issue Advances in Cellulose-Based Hydrogels)
  • Article
  • Open Access
18 Citations
3,343 Views
15 Pages

22 February 2022

The purpose of adding cellulose nanocrystals (CNCs) into sodium alginate (SA) and Antarctic krill protein (AKP) system is to use the ionic cross-linking of SA and AKP and the dynamic hydrogen-bonding between them and CNCs to construct multiple cross-...

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Gels - ISSN 2310-2861