You are currently viewing a new version of our website. To view the old version click .

Gels, Volume 8, Issue 3

March 2022 - 58 articles

Cover Story: The clinical use of human MSCs expanded on conventional microcarriers is hampered by their separation from the carrier and undesirable phenotypic changes. In this work, a tissue construct was developed for articular cartilage regeneration (ACR) based on human MSCs expanded on adult or fetal decellularized bovine articular cartilage microgels (CMGs) that do not require cell separation. In this approach, fetal or adult bovine articular cartilage was minced, decellularized, freeze-dried, ground, and sieved to produce CMGs. MSCs were subsequently expanded on CMGs to generate hMSC-loaded CMG microgels (CMG-MSCs). Then, the CMG-MSCs were suspended in sodium alginate, injected, and crosslinked to form an injectable cellular construct for ACR. The constructs showed superior chondrogenesis in vitro compared to MSCs directly encapsulated in an alginate gel. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (58)

  • Article
  • Open Access
6 Citations
3,370 Views
21 Pages

Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement

  • Anam Saleem,
  • Naveed Akhtar,
  • Muhammad Usman Minhas,
  • Arshad Mahmood,
  • Kifayat Ullah Khan and
  • Orva Abdullah

21 March 2022

In this study, we report the highly responsive chitosan-based chemically cross-linked nanomatrices, a nano-version of hydrogels developed through modified polymerization reaction for solubility improvement of poorly soluble drug simvastatin. The deve...

  • Article
  • Open Access
21 Citations
3,534 Views
20 Pages

21 March 2022

Geopolymer is a green non-metallic material with high strength and favorable properties in resistance to corrosion, fire, and high temperature, which makes it a potential substitute for Portland cement. The existing studies have primarily focused on...

  • Communication
  • Open Access
8 Citations
3,631 Views
11 Pages

21 March 2022

Strain hardening, i.e., the nonlinear elastic response of materials under load, is a physiological response of biological tissues to mechanical stimulation. It has recently been shown to play a central role in regulating cell fate. In this paper, we...

  • Article
  • Open Access
7 Citations
3,646 Views
13 Pages

Supramolecular Thixotropic Ionogel Electrolyte for Sodium Batteries

  • Shipeng Chen,
  • Li Feng,
  • Xiaoji Wang,
  • Yange Fan,
  • Yubin Ke,
  • Lin Hua,
  • Zheng Li,
  • Yimin Hou and
  • Baoyu Xue

20 March 2022

Owing to the potential of sodium as an alternative to lithium as charge carrier, increasing attention has been focused on the development of high-performance electrolytes for Na batteries in recent years. In this regard, gel-type electrolytes, which...

  • Review
  • Open Access
41 Citations
4,139 Views
12 Pages

20 March 2022

Backfill mining is the only way to realize no-waste mining and create green mines, but complicated backfill mining technology, high mining costs, and low-production capacity greatly restrict its application in low-quality iron mines. To reduce the co...

  • Article
  • Open Access
6 Citations
4,083 Views
20 Pages

19 March 2022

The self-assembly of carbohydrate-based low molecular weight gelators has led to useful advanced soft materials. The interactions of the gelators with various cations and anions are important in creating novel molecular architectures and expanding th...

  • Article
  • Open Access
38 Citations
4,840 Views
21 Pages

Orally Administered, Biodegradable and Biocompatible Hydroxypropyl–β–Cyclodextrin Grafted Poly(methacrylic acid) Hydrogel for pH Sensitive Sustained Anticancer Drug Delivery

  • Nighat Batool,
  • Rai Muhammad Sarfraz,
  • Asif Mahmood,
  • Muhammad Zaman,
  • Nadiah Zafar,
  • Ahmad Salawi,
  • Yosif Almoshari and
  • Meshal Alshamrani

19 March 2022

In the current study, a pH sensitive intelligent hydroxypropyl–β–cyclodextrin-based polymeric network (HP-β-CD-g-MAA) was developed through a solution polymerization technique for site specific delivery of cytarabine in the colo...

  • Article
  • Open Access
13 Citations
4,633 Views
19 Pages

Development and Evaluation of Ginkgo biloba/Sodium Alginate Nanocomplex Gel as a Long-Acting Formulation for Wound Healing

  • Shadab Md,
  • Samaa Abdullah,
  • Nabil A. Alhakamy,
  • Rasheed A. Shaik,
  • Basmah Medhat Eldakhakhny,
  • Ulfat Mohammad Omar,
  • Basma G. Eid,
  • Akhalakur Rahman Ansari,
  • Abdulmohsin J. Alamoudi and
  • Waleed Y. Rizg
  • + 3 authors

19 March 2022

The aim of the study was to develop and evaluate the Ginkgo biloba nanocomplex gel (GKNG) as a long-acting formulation for the wound healing potential. Pharmaceutical analysis showed an average particle size of 450.14 ± 36.06 nm for GKNG, zeta...

  • Article
  • Open Access
8 Citations
3,036 Views
12 Pages

Novel Natural Glycyrrhetinic Acid-Derived Super Metal Gel and Its Highly Selective Dyes Removal

  • Shengzhu Guo,
  • Kaize Su,
  • Huiji Yang,
  • Wende Zheng,
  • Zhen Zhang,
  • Song Ang,
  • Kun Zhang and
  • Panpan Wu

19 March 2022

Hydrogels play important roles in function materials, especially in wastewater treatment, that could solve the problems of microbial infections and dye pollutions. Herein, a natural glycyrrhetinic acid-derived gel was successfully constructed by form...

  • Article
  • Open Access
5 Citations
4,103 Views
16 Pages

18 March 2022

Mesenchymal stem cells (MSCs) possess immunomodulatory properties and capacity for endogenous regeneration. Therefore, MSC therapy is a promising treatment strategy for COVID-19. However, the cells cannot stay in the lung long enough to exert their f...

of 6

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Gels - ISSN 2310-2861