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Journal of Fungi, Volume 3, Issue 2

2017 June - 14 articles

Cover Story: A third of adults with AIDS and cryptococcal meningitis (CM) develop immune reconstitution inflammatory syndrome (IRIS) after the initiation of antiretroviral therapy (ART). We demonstrate that monocyte subset phenotype and cytokine responses prior to ART are associated with, and may be predictive of, CM–IRIS. Larger studies to further delineate innate immunological responses and the efficacy of immunomodulatory therapies during cryptococcal IRIS are warranted. View this paper
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Articles (14)

  • Review
  • Open Access
149 Citations
14,481 Views
20 Pages

7 June 2017

Chemical insecticides have been commonly used to control agricultural pests, termites, and biological vectors such as mosquitoes and ticks. However, the harmful impacts of toxic chemical insecticides on the environment, the development of resistance...

  • Article
  • Open Access
19 Citations
7,014 Views
16 Pages

Monocyte Phenotype and IFN-γ-Inducible Cytokine Responses Are Associated with Cryptococcal Immune Reconstitution Inflammatory Syndrome

  • David B. Meya,
  • Samuel Okurut,
  • Godfrey Zziwa,
  • Stephen Cose,
  • Paul R. Bohjanen,
  • Harriet Mayanja-Kizza,
  • Moses Joloba,
  • David R. Boulware,
  • Carol Yukari Manabe and
  • Edward N. Janoff
  • + 1 author

2 June 2017

A third of adults with AIDS and cryptococcal meningitis (CM) develop immune reconstitution inflammatory syndrome (IRIS) after initiating antiretroviral therapy (ART), which is thought to result from exaggerated inflammatory antigen-specific T cell re...

  • Article
  • Open Access
16 Citations
6,711 Views
12 Pages

Isolation of Ovicidal Fungi from Fecal Samples of Captive Animals Maintained in a Zoological Park

  • José A. Hernández,
  • Rosa A. Vázquez-Ruiz,
  • Cristiana F. Cazapal-Monteiro,
  • Esther Valderrábano,
  • Fabián L. Arroyo,
  • Iván Francisco,
  • Silvia Miguélez,
  • Rita Sánchez-Andrade,
  • Adolfo Paz-Silva and
  • María S. Arias

2 June 2017

Abstract: There are certain saprophytic fungi in the soil able to develop an antagonistic effect against eggs of parasites. Some of these fungal species are ingested by animals during grazing, and survive in their feces after passing through the dige...

  • Article
  • Open Access
56 Citations
10,930 Views
14 Pages

31 May 2017

For filamentous fungi (moulds), species-specific interpretive breakpoints and epidemiological cut-off values (ECVs) have only been proposed for a limited number of fungal species–antifungal agent combinations, with the result that clinical breakpoint...

  • Article
  • Open Access
731 Citations
7,537 Views
14 Pages

Innate and Adaptive Immune Defects in Chronic Pulmonary Aspergillosis

  • Felix Bongomin,
  • Chris Harris,
  • Philip Foden,
  • Chris Kosmidis and
  • David W. Denning

29 May 2017

We evaluated the expression of biomarkers of innate and adaptive immune response in correlation with underlying conditions in 144 patients with chronic pulmonary aspergillosis (CPA). Patients with complete medical and radiological records, white cell...

  • Review
  • Open Access
12 Citations
5,014 Views
10 Pages

NK Cells and Their Role in Invasive Mold Infection

  • Stanislaw Schmidt,
  • Annalisa Condorelli,
  • Antonia Koltze and
  • Thomas Lehrnbecher

19 May 2017

There is growing evidence that Natural Killer (NK) cells exhibit in vitro activity against both Aspergillus and non-Aspergillus molds. Cytotoxic molecules such as NK cell-derived perforin seem to play an important role in the antifungal activity. In...

  • Review
  • Open Access
81 Citations
8,298 Views
14 Pages

17 May 2017

The epidemiology of candidemia varies geographically, and there is still scarce data on the epidemiology of candidemia in Latin America (LA). After extensive revision of medical literature, we found reliable and robust information on the microbiologi...

  • Article
  • Open Access
5 Citations
5,580 Views
8 Pages

11 May 2017

The annual yield of matsutake mushrooms (Tricholoma matsutake) has consistently decreased in Japan over the past few decades. We used 15 polymorphic and codominant simple sequence repeat (SSR) markers, developed using next-generation sequencing, to c...

  • Review
  • Open Access
197 Citations
15,531 Views
24 Pages

Fungal Biofilms and Polymicrobial Diseases

  • Caroline B. Costa-Orlandi,
  • Janaina C. O. Sardi,
  • Nayla S. Pitangui,
  • Haroldo C. De Oliveira,
  • Liliana Scorzoni,
  • Mariana C. Galeane,
  • Kaila P. Medina-Alarcón,
  • Wanessa C. M. A. Melo,
  • Mônica Y. Marcelino and
  • Maria José S. Mendes-Giannini
  • + 2 authors

10 May 2017

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to antimicrobials and environmental...

  • Article
  • Open Access
16 Citations
6,303 Views
15 Pages

Quantitative Assessment of Grapevine Wood Colonization by the Dieback Fungus Eutypa lata

  • Cédric Moisy,
  • Gilles Berger,
  • Timothée Flutre,
  • Loïc Le Cunff and
  • Jean-Pierre Péros

6 May 2017

Eutypa lata is a fungal pathogen causing severe dieback in vineyards worldwide. This fungus colonizes vines through pruning wounds, eventually causing a brown sectorial necrosis in wood as well as stunted vegetative growth. Several years may pass bet...

  • Article
  • Open Access
27 Citations
5,963 Views
8 Pages

An Assessment of In Vitro Antifungal Activities of Efinaconazole and Itraconazole against Common Non-Dermatophyte Fungi Causing Onychomycosis

  • Ananya Tupaki-Sreepurna,
  • Bhavna T. Jishnu,
  • Vijayakishore Thanneru,
  • Savitri Sharma,
  • Anjana Gopi,
  • Murugan Sundaram and
  • Anupma Jyoti Kindo

5 May 2017

Onychomycosis is a fungal nail infection which is relatively common and difficult to treat. Treatment modalities include nail avulsion, surgical debridement and combination therapy with oral and topical antifungal drugs. In spite of a host of availab...

  • Review
  • Open Access
69 Citations
10,950 Views
11 Pages

Antifungal Susceptibility Testing of Fusarium: A Practical Approach

  • Abdullah M. S. Al-Hatmi,
  • Ilse Curfs-Breuker,
  • G. Sybren De Hoog,
  • Jacques F. Meis and
  • Paul E. Verweij

26 April 2017

In vitro susceptibility testing of Fusarium is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are t...

  • Review
  • Open Access
34 Citations
5,793 Views
15 Pages

10 April 2017

The resistance among various opportunistic Fusarium species to different antifungal agents has emerged as a cause of public health problems worldwide. Considering the significance of multi-drug resistant (MDR), this paper emphasizes the problems asso...

  • Article
  • Open Access
44 Citations
8,166 Views
10 Pages

Molecular Identification and Antifungal Susceptibility Patterns of Clinical Dermatophytes Following CLSI and EUCAST Guidelines

  • Yubhisha Dabas,
  • Immaculata Xess,
  • Gagandeep Singh,
  • Mragnayani Pandey and
  • Suneeta Meena

23 March 2017

Dermatophytes are associated with superficial infections in humans worldwide. The aim of the present study was to determine the species distribution and susceptibility patterns of clinical dermatophytes. Samples received for routine mycological proce...

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J. Fungi - ISSN 2309-608X