Table of Contents
J. Fungi, Volume 3, Issue 2 (June 2017) – 14 articles
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Cover Story (view full-size image) A third of adults with AIDS and cryptococcal meningitis (CM) develop immune reconstitution [...] Read more. A third of adults with AIDS and cryptococcal meningitis (CM) develop immune reconstitution inflammatory syndrome (IRIS) after the initiation of antiretroviral therapy (ART). We demonstrate that monocyte subset phenotype and cytokine responses prior to ART are associated with, and may be predictive of, CM–IRIS. Larger studies to further delineate innate immunological responses and the efficacy of immunomodulatory therapies during cryptococcal IRIS are warranted. View this paper