2025 April - 90 articles
Moringa oleifera (LAM) is a multipurpose tree species with extensive pharmacological and ethnomedicinal properties. Production of important medicinal plants is facing decline under changing climatic conditions, which brings along exacerbated abiotic...
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during pregn...
The environmental impact and resource demands of traditional leather manufacturing have driven the search for sustainable alternatives. Fungal mycelium leather, recognised for its eco-friendly and renewable characteristics, has emerged as a promising...
Recent studies highlight the potential of Saccharomyces species as probiotics due to their ability to modulate microbial interactions and reduce cariogenic activity, yet the underlying metabolic mechanisms remain unclear. This study investigates the...
Background: Trichophyton indotineae terbinafine-resistant infections are emerging in healthy individuals. Luliconazole, an imidazole antifungal that is effective against skin infections, faces challenges due to low water solubility and poor skin...
Phlebopus portentosus is an edible and medicinal ectomycorrhizal mushroom with delicious and high nutritional value. However, the mechanism of secondary metabolite biosynthesis in P. portentosus is still unclear. In this study, the genomics, metabolo...
Grifola frondosa, commonly known as turkey tail, is a valuable fungus with medicinal and culinary uses, rich in bioactive compounds like triterpenoid polysaccharides that contribute to health benefits. Here, we constructed a nearly complete genome of...
Hypocreales is one of the largest orders within the class Sordariomycetes and is renowned for its diversity of lifestyles, encompassing plant, insect, and human pathogens, as well as endophytes, parasites, and saprobes. In this study, we focused on s...
Cutaneous fungal infections predominantly caused by dermatophytes are a global concern. These infections vary widely by region, age, and body site, with recent shifts in the pathogen distribution. This study examines the distribution and trends of su...
The overuse of chemical fertilizers not only leads to resource wastage but also causes problems such as environmental pollution and soil degradation. In particular, crop growth in saline–sodic soils is severely restricted due to high salinity a...
Peach palm (Bactris gasipaes Kunth) is a long-lived tropical palm valued for its edible, nutritious fruits. The cultivation area of peach palm, which was introduced to Thailand for fruit production, has been steadily expanding. Small brown spots that...
Fusarium oxysporum is one of the main pathogens causing rice seedling blight disease. Revealing its pathogenic mechanism is of great significance for formulating prevention and control strategies for rice seedling blight disease. Copper transporting...
The natural regeneration of Larix gmelinii plantations plays a pivotal role in rehabilitating ecosystem services in Northeast China’s degraded forests. However, mechanistic linkages between soil aggregate nutrient fluxes and fungal community as...
Microbial protein represents a sustainable alternative to conventional animal protein, yet optimizing substrates for fungal cultivation remains critical. This study demonstrates the successful upcycling of chitin waste and aged rice into fungal prote...
Histoplasma capsulatum is a saprophytic dimorphic fungus that causes histoplasmosis, a systemic infectious disease of relevance to public health. Bats can be important agents in the epidemiological cycle of the disease since they act as reservoirs of...
Fumonisins are polyketide-derived mycotoxins posing significant health threats to humans and animals. Among these, fumonisin B1 (FB1) is the most prevalent mycotoxin, primarily produced by Fusarium verticillioides, especially in maize and its derived...
Anthracnose is a phytosanitary issue caused by various species of Colletotrichum. This study aims to revise the presence of Colletotrichum in the south of Mexico (the Soconusco area in Chiapas) and assess the inhibitory capacity of Paenibacillus sp....
The chytrid fungus, Batrachochytrium dendrobatidis (Bd), infects amphibian skin, causing chytridiomycosis, which is a contributing cause of worldwide declines and extinctions of amphibians. Relatively little is known about the roles of amphibian skin...
As an emerging and innovative technology, gene-editing technology has been widely applied in crop breeding, human disease treatment, animal model research, drug and vaccine development, and microbial engineering. We mainly introduce the development o...
Coccidioidomycosis is a fungal disease affecting humans and other mammals caused by environmental pathogens of the genus Coccidioides. Human exposure to the pathogen occurs via inhalation of spores aerosolized from soil. Thus, understanding the ecolo...
Fusarium wilt caused by Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4) is the most destructive disease of the banana. Effectors play a crucial role in Foc TR4–banana interaction; however, only a few effectors have been functionally...
Ectomycorrhizal (EcM) fungi are critical mediators of forest succession, yet the relative contributions of stochastic (neutral) and deterministic (niche-based) processes in shaping their communities are still poorly understood. We investigated the as...
Phytopathogenic fungi are important causative agents of many plant diseases, resulting in substantial economic losses in agriculture. Proteomics has become one of the most relevant high-throughput technologies, and current advances in proteomic metho...
The pathogen Alternaria alternata infects a variety of plants and crops, notably poplars, and results in large financial losses. Using twelve chemical fungicides for fungicide sensitivity tests (FSTs) on A. alternata, the result showed that proc...
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A subgroup of patients with chronic pulmonary aspergillosis (CPA) exhibits elevated serum total immunoglobulin E (IgE) levels, similar to allergic bronchopulmonary aspergillosis; however, the underlying mechanisms remain unclear. This study aimed to...
Persistent fungal pathogens remain a threat to global food security as these pathogens continue to infect crops despite different mitigating strategies. Traditionally, synthetic fungicides are used to combat these threats, but their environmental and...
L-rhamnose is one of the main monomeric sugars of rhamnogalacturonan I and II, which are polysaccharide components of pectin. In the ascomycete fungus Aspergillus niger it is metabolized through the non-phosphorylated L-rhamnose pathway, of which the...
A commercially available loop-mediated isothermal amplification assay (LAMP) for the detection of Pneumocystis jirovecii (P. jirovecii) has been evaluated for the diagnosis of Pneumocystis pneumonia (PcP) in critically ill patients. Altogether, 109 l...
In recent years, there has been an increase in the incidence of fluconazole-non-susceptible (FNS) Candida parapsilosis. The reasons why these strains are able to colonize hospitals remain unknown. It is also unclear whether these strains exhibit resi...
Equine skin mycoses are a significant concern in Kazakhstan’s livestock industry due to the country’s historical livestock farming practices, the development of equestrian sports, and food traditions. Skin infections are among the most co...
Intra-abdominal and gastrointestinal mucormycosis are less frequent than rhino-orbito-cerebral and pulmonary mucormycosis, but highly lethal. Their diagnosis remains challenging due to the non-specific clinical presentation. We collected English-lang...
The human body is colonized by diverse microorganisms, with bacteria being the most extensively studied. However, fungi, collectively known as “the mycobiota,” are increasingly recognized as integral components of the microbiota, inhabiti...
Bursaphelenchus xylophilus, the causative agent of pine wilt disease (PWD), poses a severe global threat to coniferous forests. Esteya vermicola, an endoparasitic nematophagous fungus, exhibits promising biocontrol potential against this pinewood nem...
The increasing resistance of Fusarium species to nearly all first-line antifungal agents in clinical settings has led to its designation as a ‘high-priority’ human pathogen. As a dual pathogen, Fusarium spp. threaten both human health and...
Aspergillus flavus and its secondary metabolites aflatoxins pose a significant threat to the health of humans, animals, and plants. Therefore, there is an urgent need to control A. flavus contamination. AfverB plays a key role in the aflatoxin gene c...
Diaporthe species are critical plant pathogens that contribute to a disease complex responsible for substantial yield losses in soybean production worldwide. However, reports on the primary Diaporthe species causing soybean stem blight and their sens...
(1) Background: Emerging fungal infections associated with Scedosporium spp. and Lomentospora prolificans (S/L) are becoming more frequent and are very difficult to treat. Our objective was to analyze the frequency and management of S/L isolates...
Chitinases are enzymes that catalyze the hydrolysis of chitin and play a significant biophysiological role in fungal growth, development, and pathogenesis. Valsa mali is a necrotrophic fungus that is a primary contributor to apple Valsa canker. Our s...
Insects are the largest animal group in nature, with significant effects on ecology, human health, and indigenous flora and fauna [...]
Macrofungi are key decomposers of organic matter and play an active role in biogeochemical cycles, thereby contributing to carbon sequestration in forest ecosystems. Floodplain forests (várzeas) are characterized by the dynamics of rising and...
Tinea nigra (TN) is a superficial fungal infection caused by the melanized fungus Hortaea werneckii, characterized by irregular dark patches, typically on the palms. This systematic review aims to evaluate the epidemiology, demographic characteristic...
Caves can be regarded as extreme environments, and fungi are known as omnipresent and highly adaptable organisms that can easily colonize such environments. The primary objective of this study was to use the statistical analysis of sequences stored i...
An in vitro 3D model using fungus colonized Reconstructed Human Epidermis (RHE) represents an effective preclinical model to simulate the pathological conditions of onychomycosis. We evaluated the suitability of this 3D onychomycosis model and use it...
Candida glabrata is an opportunistic, pathogenic fungus that is increasingly isolated from hospitalized patients. The incidence of drug tolerance, heteroresistance, and resistance is on the rise due to an overuse of antifungal drugs. The aim of this...
Recently, Fusarium root rot (FRR)-like symptoms were observed in Uganda’s agroecology zones, prompting the National Agricultural Organisation (NARO) to conduct a disease survey. The survey reports indicated FRR as the second most prevalent root...
Codon optimization is a widely employed strategy to enhance protein expression. However, it occasionally leads to unexpected transcriptional repression despite preserving amino acid sequences. This study investigates the mechanistic basis of such tra...
Invasive fungal diseases are a significant threat in immunocompromised patients, underscoring the need for rapid and accurate diagnostics. This study describes the development and validation of a real-time PCR-based laboratory-developed assay (LDA) o...
The aim of this study is to share our experience regarding the diagnosis and therapeutic management of primary cutaneous aspergillosis (PCA) in the burn patient, an uncommon infection associated with increased mortality, morbidity, and treatment cost...
The human gastrointestinal tract harbors a vast array of microorganisms, which play essential roles in maintaining metabolic balance and immune function. While bacteria dominate the gut microbiome, fungi represent a much smaller, often overlooked fra...
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