Bioengineering, Volume 7, Issue 1 (March 2020) – 29 articles
Cover Story (view full-size image): Mechanical environments surrounding cancer cells, which include stiffness of the extracellular matrix, are altered during tumor progression and influence cell behaviors. In this study, we show that stiff matrices, through activation of the mechanotransducer YAP, increase the expression of MMP24, which encodes the membrane-type matrix metaroprotease-24. In addition, based on the human protein atlas database, high MMP24 expression is correlated with the prolonged overall survival rate of patients for several cancers, including breast cancer. View this paper.
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.