March 2025 - 114 articles
The construction of artificial microorganisms often relies on the transfer of genomes from donor to acceptor cells. This synthetic biology approach has been considerably fostered by the J. Craig Venter Institute but apparently depends on the use of m...
The increasing global demand for natural substances such as the sesquiterpene α-humulene makes optimizing microbial production essential. A production process using the versatile host Cupriavidus necator has been recently improved by adjusting...
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, with immunotherapy being a first-line treatment at the advanced stage and beyond. Hypoxia plays a critical role in tumor progression and resistance to therapy. This study dev...
The aim of this study was to predict Bruch’s membrane opening-minimum rim Width (BMO-MRW), a relatively new parameter using conventional optical coherence tomography (OCT) parameter, using retinal nerve fibre layer (RNFL) thickness and visual f...
Over the last several decades, computational biomechanics has been intensively investigated as part of the study of human body systems (musculoskeletal, cardiovascular, digestive, etc [...]
Intra-experimental factor setting shifts in intensified design of experiments (iDoE) enhance understanding of bioproduction processes by capturing their dynamics and are thus essential to fulfill quality by design (QbD) ambitions. Determining the inf...
Cranial sutures play critical roles in load distribution and neuroprotection, with their biomechanical performance intimately linked to morphological complexity. The purpose of this study was to investigate the effect of different morphologies of cra...
Background: Hallux limitus (HL) is a condition marked by the restricted dorsiflexion of the first metatarsophalangeal joint, causing pain and functional limitations, especially during the propulsive phase of walking. This restriction affects the gait...
The purpose of this paper is to provide researchers with a description of a data library representing human interaction with medium- to large-sized objects in everyday life. The library includes motion capture data characterizing human and object mot...
Scaffolds are critical in regenerative medicine, particularly in bone tissue engineering, where they mimic the extracellular matrix to support tissue regeneration. Scaffold efficacy depends on precise control of 3D printing parameters, which determin...
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