You are currently viewing a new version of our website. To view the old version click .

Bioengineering, Volume 12, Issue 2

February 2025 - 116 articles

Cover Story: Critical-sized bone defects, which can result from trauma, infection, or tumor removal, present major challenges for orthopedic surgeons. Current treatments like bone grafts have significant limitations such as donor site complications and variable outcomes. Regional gene therapy has emerged as a promising solution that combines genetic engineering with tissue engineering principles. This approach involves either directly delivering therapeutic genes to the defect site or implanting genetically modified stem cells that produce bone-forming proteins. Such stem cells can be obtained from various sources including bone marrow, fat, or muscle tissue. This strategy aims to provide all the essential components for bone repair while minimizing the complications associated with the current treatments. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (116)

  • Review
  • Open Access
3 Citations
9,496 Views
13 Pages

Different Oral Appliance Designs Demonstrate Different Rates of Efficacy for the Treatment of Obstructive Sleep Apnea: A Review Article

  • Leonard A. Liptak,
  • Edward Sall,
  • Sung Kim,
  • Erin Mosca,
  • Shouresh Charkhandeh and
  • John E. Remmers

Obstructive Sleep Apnea afflicts an estimated 1 billion people worldwide. Untreated, Obstructive Sleep Apnea is linked with elevated levels of mortality, decreased quality of life and increased economic costs. However, several large population studie...

  • Article
  • Open Access
869 Views
19 Pages

The objective of this research was to develop a coded language, similarly to Morse or Braille, via a haptic thermal interface. The method is based on the human thermal sense to receive and decode the messages, and is to be used as an alternative or c...

  • Review
  • Open Access
16 Citations
11,776 Views
57 Pages

Neuro-Nutrition and Exercise Synergy: Exploring the Bioengineering of Cognitive Enhancement and Mental Health Optimization

  • Vicente Javier Clemente-Suárez,
  • Alexandra Martín-Rodríguez,
  • Agustín Curiel-Regueros,
  • Alejandro Rubio-Zarapuz and
  • José Francisco Tornero-Aguilera

The interplay between nutrition, physical activity, and mental health has emerged as a frontier in bioengineering research, offering innovative pathways for enhancing cognitive function and psychological resilience. This review explores the neurobiol...

  • Editorial
  • Open Access
2 Citations
2,301 Views
4 Pages

This Special Issue of Bioengineering is dedicated to the profound impact of big data and artificial intelligence (AI) in the fields of biomedical research and healthcare. In an age defined by the rapid evolution of technology, this Issue explores the...

  • Article
  • Open Access
1 Citations
2,535 Views
31 Pages

Development of Mathematical Model for Understanding Microcirculation in Diabetic Foot Ulcers Based on Ankle–Brachial Index

  • Ana Karoline Almeida da Silva,
  • Gustavo Adolfo Marcelino de Almeida Nunes,
  • Rafael Mendes Faria ,
  • Mário Fabrício Fleury Rosa,
  • Lindemberg Barreto Mota da Costa,
  • Newton de Faria,
  • Adson Ferreira da Rocha ,
  • José Carlos Tatmatsu-Rocha and
  • Suelia de Siqueira Rodrigues Fleury Rosa

This study proposes an innovative mathematical model for assessing microcirculation in patients with diabetic ulcers, using the ankle–brachial index (ABI). The methodology combines Bond Graph (BG) modeling and Particle Swarm Optimization (PSO),...

  • Review
  • Open Access
6 Citations
4,017 Views
30 Pages

Inflammatory Cell-Targeted Delivery Systems for Myocardial Infarction Treatment

  • Wenyuan Zhang,
  • Dan Peng,
  • Shiqi Cheng,
  • Rui Ni,
  • Meiyang Yang,
  • Yongqing Cai,
  • Jianhong Chen,
  • Fang Liu and
  • Yao Liu

Myocardial infarction (MI) is a cardiovascular disease (CVD) with high morbidity and mortality worldwide, which is a serious threat to human life and health. Inflammatory and immune responses are initiated immediately after MI, and unbalanced inflamm...

  • Systematic Review
  • Open Access
4 Citations
2,648 Views
12 Pages

Exploring the Impact of Socially Assistive Robots in Rehabilitation Scenarios

  • Arianna Carnevale,
  • Alessandra Raso,
  • Carla Antonacci,
  • Letizia Mancini,
  • Alessandra Corradini,
  • Alice Ceccaroli,
  • Carlo Casciaro,
  • Vincenzo Candela,
  • Alessandro de Sire and
  • Pieter D’Hooghe
  • + 1 author

Background: Socially Assistive Robots (SARs) represent an innovative approach in rehabilitation technology, significantly enhancing the support and motivation for individuals across diverse rehabilitation settings. Despite their growing utilization,...

  • Article
  • Open Access
1,560 Views
18 Pages

Round Well Inset for Uniform Electric Field Distribution in Electroporation Applications

  • Praveen Sahu,
  • Marco Barozzi,
  • Paolo Di Barba,
  • Maria Evelina Mognaschi,
  • Monica La Mura,
  • Patrizia Lamberti,
  • Michele Forzan,
  • Maria Teresa Conconi,
  • Ignacio Camarillo and
  • Raji Sundararajan
  • + 1 author

Uniform electric field distribution in electroporation is crucial for achieving the effective localized delivery of drug molecules. Currently, in vitro electroporation studies on adherent cells lack a standardized test setup for obtaining consistent...

  • Article
  • Open Access
1 Citations
4,018 Views
11 Pages

Carrying external loads, such as vest-borne systems, is common in occupations like firefighting and military service, yet the physiological impacts of load placement, mass, and walking conditions remain not fully understood. This study examined the e...

  • Article
  • Open Access
3 Citations
2,176 Views
18 Pages

There is a growing need to predict the severity of vitamin D deficiency (VDD) through non-invasive methods due to its significant global health concerns. For vitamin D-level assessments, the 25-hydroxy vitamin D (25-OH-D) blood test is the standard,...

of 12

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Bioengineering - ISSN 2306-5354