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Medicines, Volume 5, Issue 3

September 2018 - 48 articles

Cover Story: The genus Juniperus has attracted great interest in the scientific community since these plants have many uses in folk medicine. A wide range of published results about the medicinal applications of Juniperus species and the biological activities of their metabolites provide more evidence that these species are applicable to the development of new natural medicines. They are also a source of unique natural chemical structures. For example, from Juniperus brevifolia (Seub.) Antoine, an endemic tree of the Azores locally known as ‘‘cedro-do-mato’’, several secondary metabolites with a unique chemical structure were isolated and identified. View this paper.
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Articles (48)

  • Article
  • Open Access
18 Citations
5,178 Views
12 Pages

Effects of Shugan-Jianpi Recipe on the Expression of the p38 MAPK/NF-κB Signaling Pathway in the Hepatocytes of NAFLD Rats

  • Yuanjun Deng,
  • Kairui Tang,
  • Runsen Chen,
  • Yajie Liu,
  • Huan Nie,
  • Hong Wang,
  • Yupei Zhang and
  • Qinhe Yang

19 September 2018

Background: In traditional Chinese medicine, the Shugan-Jianpi recipe is often used in the treatment of nonalcoholic fatty liver disease (NAFLD). This study aimed to explore the mechanism of the Shugan-Jianpi recipe in relation to rats with NAFLD ind...

  • Feature Paper
  • Article
  • Open Access
17 Citations
6,016 Views
18 Pages

18 September 2018

Background: Gac (Momordica cochinchinensis Spreng) seeds have long been used in traditional medicine as a remedy for numerous conditions due to a range of bioactive compounds. This study investigated the solvent extraction of compounds that could be...

  • Article
  • Open Access
54 Citations
7,070 Views
16 Pages

Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery

  • Pawan Kumar,
  • Shailendra Kumar Singh,
  • Vandana Handa and
  • Himanshu Kathuria

14 September 2018

Current topical minoxidil (MXD) formulations involve an unpleasant organic solvent which causes patient incompliance in addition to side effects in some cases. Therefore, the objective of this work was to develop an MXD formulation providing enhanced...

  • Communication
  • Open Access
15 Citations
5,355 Views
12 Pages

10 September 2018

Three recent studies revealed synergy between immune-checkpoint inhibitors and the microbiome as a new approach in the treatment of cancer. Incidentally, there has been significant progress in understanding the role of polyunsaturated fatty acids (PU...

  • Review
  • Open Access
60 Citations
9,759 Views
14 Pages

7 September 2018

The human microbiome plays many roles in inflammation, drug metabolism, and even the development of cancer that we are only beginning to understand. Colorectal cancer has been a focus for study in this field as its pathogenesis and its response to tr...

  • Article
  • Open Access
17 Citations
6,344 Views
16 Pages

Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients

  • Anja Thronicke,
  • Shiao Li Oei,
  • Antje Merkle,
  • Harald Matthes and
  • Friedemann Schad

6 September 2018

Background: Despite improvement of tumor response rates, targeted therapy may induce toxicities in cancer patients. Recent studies indicate amelioration of adverse events (AEs) by add-on mistletoe (Viscum album L., VA) in standard oncological treatme...

  • Review
  • Open Access
336 Citations
44,383 Views
13 Pages

4 September 2018

Nowadays, there is an interest in the consumption of food without synthetic additives and rather with the use of natural preservatives. In this regard, natural extracts of the Lamiaceae family, such as rosemary, have been studied because of its bioac...

  • Editorial
  • Open Access
1 Citations
4,292 Views
4 Pages

4 September 2018

This Medicines special issue focuses on the further investigation, development, and modernization of acupuncture in basic research settings, as well as in clinical applications. The special issue contains 12 articles reporting latest evidence-based r...

  • Editorial
  • Open Access
8 Citations
4,836 Views
3 Pages

3 September 2018

This editorial adopts a future-oriented technology. It describes a new modern helmet for transcranial laser stimulation and a way to quantify effects of this possible therapeutical method using near-infrared spectroscopy.

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Medicines - ISSN 2305-6320