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Open AccessReview

Probiotics in the Treatment of Colorectal Cancer

Department of Hematology and Oncology, Stony Brook University Hospital, Stony Brook, New York, NY 11794, USA
Author to whom correspondence should be addressed.
Medicines 2018, 5(3), 101;
Received: 20 August 2018 / Revised: 5 September 2018 / Accepted: 5 September 2018 / Published: 7 September 2018
(This article belongs to the Special Issue Natural Compounds as New Cancer Treatments)
PDF [735 KB, uploaded 7 September 2018]


The human microbiome plays many roles in inflammation, drug metabolism, and even the development of cancer that we are only beginning to understand. Colorectal cancer has been a focus for study in this field as its pathogenesis and its response to treatment have both been linked to the functioning of microbiota. This literature review evaluates the animal and human studies that have explored this relationship. By manipulating the microbiome with interventions such as probiotic administration, we may be able to reduce colorectal cancer risk and improve the safety and effectiveness of cancer therapy even though additional clinical research is still necessary. View Full-Text
Keywords: probiotics; synbiotics; microbiome; microbiota; colorectal cancer probiotics; synbiotics; microbiome; microbiota; colorectal cancer

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Hendler, R.; Zhang, Y. Probiotics in the Treatment of Colorectal Cancer. Medicines 2018, 5, 101.

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