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Toxics, Volume 7, Issue 1

2019 March - 18 articles

Cover Story: Particulate matter (PM) exposure and the coexisting high prevalence of metabolic syndrome (MetSyn) pose significant threats to human health. PM exposure, which is known to induce pulmonary and systemic inflammation, has been implicated in the pathogenesis of MetSyn and cardiopulmonary diseases. Moreover, individuals with pre-existing MetSyn may be more susceptible to the detrimental effects of PM exposure. The aim of this narrative review is to provide an overview of MetSyn/PM-induced systemic inflammation in cardiopulmonary diseases. View Paper here.
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Articles (18)

  • Article
  • Open Access
14 Citations
6,368 Views
16 Pages

Propensity of Tagetes erecta L., a Medicinal Plant Commonly Used in Diabetes Management, to Accumulate Perfluoroalkyl Substances

  • John Baptist Nzukizi Mudumbi,
  • Adegbenro Peter Daso,
  • Okechukwu Jonathan Okonkwo,
  • Seteno Karabo Obed Ntwampe,
  • Tandi E. Matsha,
  • Lukhanyo Mekuto,
  • Elie Fereche Itoba-Tombo,
  • Adewole T. Adetunji and
  • Linda L. Sibali

25 March 2019

It has been extensively demonstrated that plants accumulate organic substances emanating from various sources, including soil and water. This fact suggests the potentiality of contamination of certain vital bioresources, such as medicinal plants, by...

(This article belongs to the Section Environmental Chemistry)
  • Feature Paper
  • Review
  • Open Access
62 Citations
8,024 Views
18 Pages

25 March 2019

Living organisms respond to environmental changes and xenobiotic exposures by regulating gene expression. While heat shock, unfolded protein, and DNA damage stress responses are well-studied at the levels of the transcriptome and proteome, tRNA-media...

(This article belongs to the Special Issue Biomarkers of Environmental Toxicants)
  • Perspective
  • Open Access
32 Citations
11,132 Views
14 Pages

19 March 2019

Aristolochic acids (AAs) are nitrophenanthrene carboxylic acids naturally produced by Aristolochia plants. These plants were widely used to prepare herbal remedies until AAs were observed to be highly nephrotoxic and carcinogenic to humans. Although...

(This article belongs to the Special Issue Biomarkers of Environmental Toxicants)
  • Review
  • Open Access
125 Citations
12,927 Views
18 Pages

19 March 2019

Industrial advances have led to generation of multi-component chemicals, materials and pharmaceuticals which are directly or indirectly affecting the environment. Although toxicity data are available for individual chemicals, generally there is no to...

(This article belongs to the Special Issue Toxicity of Chemical Mixtures)
  • Feature Paper
  • Review
  • Open Access
79 Citations
14,920 Views
28 Pages

19 March 2019

DNA adducts are believed to play a central role in the induction of cancer in cigarette smokers and are proposed as being potential biomarkers of cancer risk. We have summarized research conducted since 2012 on DNA adduct formation in smokers. A vari...

(This article belongs to the Special Issue Biomarkers of Environmental Toxicants)
  • Article
  • Open Access
11 Citations
5,014 Views
14 Pages

10 March 2019

Environmental research has widely utilized the ambient concentrations of hazardous air pollutants (HAPs) modeled by the National-Scale Air Toxics Assessment (NATA) program; however, limited studies have evaluated the model’s performance. This s...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Review
  • Open Access
55 Citations
11,579 Views
16 Pages

Environmental Contaminants Exposure and Preterm Birth: A Systematic Review

  • Maria Grazia Porpora,
  • Ilaria Piacenti,
  • Sara Scaramuzzino,
  • Luisa Masciullo,
  • Francesco Rech and
  • Pierluigi Benedetti Panici

1 March 2019

Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic...

(This article belongs to the Special Issue Prenatal Exposure to Toxics and Risks in Infants)
  • Article
  • Open Access
29 Citations
5,320 Views
8 Pages

Effects of AgNPs on the Snail Biomphalaria glabrata: Survival, Reproduction and Silver Accumulation

  • Eduardo Cyrino Oliveira-Filho,
  • Daphne Heloísa de Freitas Muniz,
  • Esther Lima de Carvalho,
  • Paolin Rocio Cáceres-Velez,
  • Maria Luiza Fascineli,
  • Ricardo Bentes Azevedo and
  • Cesar Koppe Grisolia

1 March 2019

Silver nanoparticles (AgNPs) are used intensively in medical and industrial applications. Environmental concerns have arisen from the potential release of this material into aquatic ecosystems. The aims of this research were to evaluate the potential...

(This article belongs to the Special Issue Nanoparticles Toxicity and Impacts on Biodiversity)
  • Article
  • Open Access
8 Citations
7,523 Views
18 Pages

Magnesium Fluoride Forms Unique Protein Corona for Efficient Delivery of Doxorubicin into Breast Cancer Cells

  • Hamed Al-Busaidi,
  • Md. Emranul Karim,
  • Syafiq Asnawi Zainal Abidin,
  • Kyi Kyi Tha and
  • Ezharul Hoque Chowdhury

22 February 2019

Background: The efficacy of chemotherapy is undermined by adverse side effects and chemoresistance of target tissues. Developing a drug delivery system can reduce off-target side effects and increase the efficacy of drugs by increasing their accumula...

(This article belongs to the Section Toxicology)
  • Review
  • Open Access
15 Citations
11,476 Views
17 Pages

Opioid Use in Pregnant Women and Neonatal Abstinence Syndrome—A Review of the Literature

  • Fábio Martins,
  • David Oppolzer,
  • Catarina Santos,
  • Mário Barroso and
  • Eugenia Gallardo

16 February 2019

Opiate use during pregnancy has been an increasing problem over the last two decades, making it an important social and health concern. The use of such substances may have serious negative outcomes in the newborn, and clinical and cognitive condition...

(This article belongs to the Special Issue Prenatal Exposure to Toxics and Risks in Infants)
  • Article
  • Open Access
9 Citations
4,312 Views
13 Pages

13 February 2019

A simple microextraction method, magnetic stirring assisted demulsification dispersive liquid–liquid microextraction, for preconcentration of five polycyclic aromatic hydrocarbons (fluorene, phenanthrene, anthracene, fluoranthrene, and pyrene)...

(This article belongs to the Special Issue Analysis of Chemical Contaminants in Food)
  • Feature Paper
  • Article
  • Open Access
20 Citations
6,236 Views
13 Pages

Internal Doses of Glycidol in Children and Estimation of Associated Cancer Risk

  • Jenny Aasa,
  • Efstathios Vryonidis,
  • Lilianne Abramsson-Zetterberg and
  • Margareta Törnqvist

1 February 2019

The general population is exposed to the genotoxic carcinogen glycidol via food containing refined edible oils where glycidol is present in the form of fatty acid esters. In this study, internal (in vivo) doses of glycidol were determined in a cohort...

(This article belongs to the Special Issue Biomarkers of Environmental Toxicants)
  • Review
  • Open Access
49 Citations
7,791 Views
13 Pages

Metabolic Syndrome and Air Pollution: A Narrative Review of Their Cardiopulmonary Effects

  • Emily A. Clementi,
  • Angela Talusan,
  • Sandhya Vaidyanathan,
  • Arul Veerappan,
  • Mena Mikhail,
  • Dean Ostrofsky,
  • George Crowley,
  • James S. Kim,
  • Sophia Kwon and
  • Anna Nolan

30 January 2019

Particulate matter (PM) exposure and metabolic syndrome (MetSyn) are both significant global health burdens. PM exposure has been implicated in the pathogenesis of MetSyn and cardiopulmonary diseases. Individuals with pre-existing MetSyn may be more...

(This article belongs to the Section Toxicology)
  • Review
  • Open Access
133 Citations
14,232 Views
11 Pages

24 January 2019

Endocrine Disruptor Compounds (EDCs) are synthetic or natural molecules in the environment that promote adverse modifications of endogenous hormone regulation in humans and/or in wildlife animals. In the present paper, we review the potential mechani...

(This article belongs to the Section Toxicology)
  • Case Report
  • Open Access
24 Citations
8,600 Views
9 Pages

22 January 2019

In Taiwan and other countries, glyphosate has been used widely as a non-selective herbicide over 40 years in crop lands and non-crop lands. However, public concerns about its environmental and health risks have increased rapidly because the Internati...

  • Article
  • Open Access
34 Citations
8,193 Views
14 Pages

17 January 2019

The uptake of trace elements by wild herbaceous plants in a multiple trace element-contaminated site was investigated. The bioaccumulation factor (BF) of trace elements was markedly variable among the different plant species. On average, the BF for v...

  • Article
  • Open Access
54 Citations
10,664 Views
13 Pages

Potential Antagonistic Effects of Acrylamide Mitigation during Coffee Roasting on Furfuryl Alcohol, Furan and 5-Hydroxymethylfurfural

  • Dirk W. Lachenmeier,
  • Steffen Schwarz,
  • Jan Teipel,
  • Maren Hegmanns,
  • Thomas Kuballa,
  • Stephan G. Walch and
  • Carmen M. Breitling-Utzmann

21 December 2018

The four heat-induced coffee contaminants—acrylamide, furfuryl alcohol (FA), furan and 5-hydroxymethylfurfural (HMF)—were analyzed in a collective of commercial samples as well as in Coffea arabica seeds roasted under controlled condition...

(This article belongs to the Special Issue Analysis of Chemical Contaminants in Food)
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Toxics - ISSN 2305-6304