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Toxics, Volume 6, Issue 1

March 2018 - 18 articles

Cover Story: Health threat from cadmium contamination of our dietary staples and the air we breathe. Cadmium is a highly persistent environmental toxicant that also has higher rates of soil-to-plant transfer than lead and mercury. Humans are exposed to cadmium in dietary staples (rice, potato and wheat), cigarette smoke and polluted air. There are no therapeutically effective chelating agents to reduce the body content of cadmium. Public measures are required to minimize cadmium contamination of the food-chain to reduce health risk and to prevent the development of cadmium-associated diseases such as chronic kidney disease, bone fragility, and macular degeneration, a leading cause of blindness in adults. View the paper
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Articles (18)

  • Article
  • Open Access
2 Citations
5,222 Views
12 Pages

19 March 2018

The aim of this study is the application of a software tool to the design of stripping columns to calculate the removal of trihalomethanes (THMs) from drinking water. The tool also allows calculating the rough capital cost of the column and the decre...

  • Article
  • Open Access
14 Citations
5,740 Views
7 Pages

16 March 2018

Background: Few studies have investigated the association between radon and thyroid cancer despite the sensitivity of the thyroid gland to radiation. Our goal is to investigate the association between county-level radon and incidence of female thyroi...

  • Feature Paper
  • Article
  • Open Access
75 Citations
7,688 Views
14 Pages

Cadmium Nephrotoxicity Is Associated with Altered MicroRNA Expression in the Rat Renal Cortex

  • Michael J. Fay,
  • Lauren A. C. Alt,
  • Dominika Ryba,
  • Ribhi Salamah,
  • Ryan Peach,
  • Alexander Papaeliou,
  • Sabina Zawadzka,
  • Andrew Weiss,
  • Nil Patel and
  • Asad Rahman
  • + 4 authors

15 March 2018

Cadmium (Cd) is a nephrotoxic environmental pollutant that causes a generalized dysfunction of the proximal tubule characterized by polyuria and proteinuria. Even though the effects of Cd on the kidney have been well-characterized, the molecular mech...

  • Feature Paper
  • Review
  • Open Access
294 Citations
21,786 Views
23 Pages

10 March 2018

Cadmium (Cd) is a food-chain contaminant that has high rates of soil-to-plant transference. This phenomenon makes dietary Cd intake unavoidable. Although long-term Cd intake impacts many organ systems, the kidney has long been considered to be a crit...

  • Article
  • Open Access
4 Citations
4,633 Views
14 Pages

9 February 2018

The aim of this work is to prepare a proposal for the post-authorization monitoring (PAM) of veterinary medicinal products (VMP), in particular parasiticides. Such a monitoring might especially be useful for parasiticides identified as Persistence Bi...

  • Article
  • Open Access
22 Citations
6,004 Views
15 Pages

Hematological Abnormality, Oxidative Stress, and Genotoxicity Induction in the Greenhouse Pesticide Sprayers; Investigating the Role of NQO1 Gene Polymorphism

  • Nahid Ahmadi,
  • Ali Mandegary,
  • Akram Jamshidzadeh,
  • Mohaddeseh Mohammadi-Sardoo,
  • Mohammadreza Mohammadi-Sardo,
  • Elham Salari and
  • Leyla Pourgholi

7 February 2018

The widespread use of pesticides in agriculture represents a threat to the human populations exposed to them. In this cross-sectional study, the hematological and biochemical parameters, plasma cholinesterase (PChE) activity, oxidative stress, genoto...

  • Article
  • Open Access
21 Citations
4,341 Views
17 Pages

5 February 2018

Pharmacotherapy as the mainstay in the management of breast cancer has demonstrated various drawbacks, including non-targeted bio distribution and narrow therapeutic and safety windows. Thus, enhancements in pharmacodynamic and pharmacokinetic profil...

  • Article
  • Open Access
15 Citations
6,308 Views
11 Pages

Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment

  • Samantha A. Radford,
  • Parinya Panuwet,
  • Ronald E. Hunter Jr.,
  • Dana Boyd Barr and
  • P. Barry Ryan

2 February 2018

Since urinary insecticide metabolites are commonly used as biomarkers of exposure, it is important that we quantify whether insecticides degrade in food and beverages in order to better perform risk assessment. This study was designed to quantify deg...

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Toxics - ISSN 2305-6304