Toxics 2018, 6(1), 11; https://doi.org/10.3390/toxics6010011
Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment
Samantha A. Radford 1,2,3,*
, Parinya Panuwet 2, Ronald E. Hunter Jr. 2,4, Dana Boyd Barr 2 and P. Barry Ryan 1,2
, Parinya Panuwet 2, Ronald E. Hunter Jr. 2,4, Dana Boyd Barr 2 and P. Barry Ryan 1,21
Department of Chemistry, Emory University, Atlanta, GA 30322, USA
2
Laboratory for Exposure Assessment and Development for Environmental Research, Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
3
Department of Chemistry, Saint Francis University, Loretto, PA 15940, USA
4
Analytical Services Lab—Americas, The Coca-Cola Company, Atlanta, GA 30313, USA
*
Author to whom correspondence should be addressed.
Received: 8 November 2017 / Revised: 29 January 2018 / Accepted: 30 January 2018 / Published: 2 February 2018
(This article belongs to the Special Issue Pesticide Environmental Risk Assessments)
Abstract
Since urinary insecticide metabolites are commonly used as biomarkers of exposure, it is important that we quantify whether insecticides degrade in food and beverages in order to better perform risk assessment. This study was designed to quantify degradation of organophosphorus and pyrethroid insecticides in beverages. Purified water, white grape juice, orange juice, and red wine were fortified with 500 ng/mL diazinon, malathion, chlorpyrifos, permethrin, cyfluthrin, cypermethrin, and deltamethrin, and aliquots were extracted several times over a 15-day storage period at 2.5 °C. Overall, statistically significant loss of at least one insecticide was observed in each matrix, and at least five out of seven insecticides demonstrated a statistically significant loss in all matrices except orange juice. An investigation of an alternative mechanism of insecticide loss—adsorption onto the glass surface of the storage jars—was carried out, which indicated that this mechanism of loss is insignificant. Results of this work suggest that insecticides degrade in these beverages, and this degradation may lead to pre-existing insecticide degradates in the beverages, suggesting that caution should be exercised when using urinary insecticide metabolites to assess exposure and risk. View Full-TextKeywords:
pesticides; degradation; biomarkers of exposure; risk assessment; GC-ECD
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Radford, S.A.; Panuwet, P.; Hunter Jr., R.E.; Barr, D.B.; Ryan, P.B. Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment. Toxics 2018, 6, 11.
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