Table of Contents
Biomolecules, Volume 9, Issue 7 (July 2019)
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Cover Story (view full-size image) The rod and the hook are structural components of the bacterial flagellum, a filamentous organelle [...] Read more. The rod and the hook are structural components of the bacterial flagellum, a filamentous organelle for motility. The distal rod and the hook are similar helical assemblies of homologous proteins, FlgG and FlgE, respectively, but they show distinct mechanical characteristics. The rod is a rigid drive shaft whereas the hook is a universal joint with high bending flexibility. Our new rod model reveals that an extending segment, L-stretch, mediates extensive interactions with neighboring subunits (the left panel). In contrast, L-stretch of the hook is short and mediates fewer interactions (the right panel). These structures suggest that the L-stretch plays a key role in achieving the distinct mechanical properties of the rod and the hook. View this paper.