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Special Issue "Plant-Derived Natural Compounds in the Management of Cancer: Significance and Challenges"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 31 December 2019.
Interests: (neuro-)physiology; pharmacology and cell signaling; anti-cancer drugs; natural compounds
Interests: Oxidant Stress and Myocardial Angiogenesis; Oxidant Stress and ER stress in Diabetes/Hyperglycemia mediated Endothelial Dysfunction's
Interests: experimental mammary carcinogenesis, chemoprevention, therapy, animal models, plant-derived funtional foods, cancer cell signaling
Cancer is a major disease worldwide, contributing significantly to the social and economic burden. Therefore, there is an unmet need to develop cancer prevention strategies for those at risk and improve treatment strategies for the benefit of those that are already affected. Although several mechanisms have been proposed for the development and progression of various cancers, there remain areas that need to be explored and an urgency to tackle these processes (using anti-cancer drugs) to reduce the development and progression of cancers and improve the efficacy of cancer treatments.
Cancers often develop over years or even decades, triggered by different processes involving DNA damage, chronic inflammation, comprehensive interaction between relevant molecular pathways, and cellular cross-talk with the neighboring tissues. Only a minor part of cancers are caused by inborn pre-disposition. The absolute majority carry a sporadic character based on modifiable risk factors which play a central role in cancer prevention. Numerous studies have documented that dietary natural plant products (both whole products as well as their isolated active compounds) are able to affect the initiation, promotion, and progression of cancers. The long-term administration of multi-target phytochemicals with a plethora of biological activities can thus be the most rational and effective strategy used in medical practice in this regard.
This Special Issue focusses on the effects of plant-derived dietary factors on carcinogenesis and effective cancer treatment. It includes in-vitro- and in-vivo-based cancer models evaluating the mechanisms of action of phytochemicals on cancer; clinical investigations on the role of the plant compounds on cancer risk, treatment, and survival; novel methodological approaches to enhance the bioavailability of phytochemicals; and novel strategies for the extraction, purification, and characterization natural compounds with anticancer activity. For this Special Issue, we invite original research articles and reviews related to the role of plant-derived natural compounds on cancers.
Dr. Dietrich Büsselberg
Dr. Samson Mathews Samuel
Dr. Peter Kubatka
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cancer cells
- cancer chemoprevention
- cancer stem cells
- cancer treatment
- cell cycle regulation
- epigenetic modulators
- geno-protective effects
- natural bioactive compounds
- oxidative stress
- plant functional foods